Brigrel 60 Tablet belongs to the antiplatelet drugs (blood thinners) primarily taken to prevent heart attack or stroke in people at high risk of heart disease. Brigrel 60 Tablet  helps to prevent blood clots in people with acute coronary syndrome (heart doesn't receive enough oxygen) who have had stents placed in blood vessels in their heart. A heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of cholesterol, fat, and other substances, which form plaque in the arteries that feed the heart (coronary arteries). A heart attack signs include chest pain, upper body pain, sweating, nausea, fatigue, and trouble breathing.

Brigrel 60 Tablet contains Ticagrelor, which is a blood thinner that prevents clot formation in the blood vessels. Platelets are blood cells that stick together and block any cuts and breaks in blood vessels. But platelets can stick together inside already narrowed blood vessels to form a clot in people at risk of heart attack or stroke. The clot can stop blood from flowing to the heart or brain and cause a heart attack or stroke. Here, Brigrel 60 Tablet slows the blood's clotting action by making platelets less sticky.

Your doctor will advise you how often you take Brigrel 60 Tablet based on your medical condition. In some cases, you may experience dyspnea (shortness of breath), tightness in the chest, blurred vision, nosebleeds, dizziness, faintness, or lightheadedness. If side effects are persistent, talk to your doctor. Brigrel 60 Tablet may cause you to bleed more easily. You should not take Brigrel 60 Tablet if you have bleeding in your brain, a problem with blood flow, or any other bleeding risk factor.

Before taking the Brigrel 60 Tablet , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. Brigrel 60 Tablet should not be stopped even if you feel better without consulting your doctor, as stopping a sudden intake of Brigrel 60 Tablet may worsen your condition and increase the risk of a future heart attack. The patient should inform the doctor that they are taking Brigrel 60 Tablet before any surgery is scheduled or any new medicine is taken. Don't take Brigrel 60 Tablet before or after having heart bypass surgery. Before using Brigrel 60 Tablet , consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Brigrel 60 Tablet is an antiplatelet (blood thinner) and plays a vital role in preventing the formation of harmful blood clots in your blood vessels. Brigrel 60 Tablet work by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. Thus, it reduces the risk of heart attack, stroke, and acute coronary syndrome (heart doesn't receive enough oxygen or blood) in heart disease patients and patients who have undergone recent heart surgery with a stent.

• Dyspnea (shortness of breath)
• Tightness in the chest
• Blurred vision
• Nosebleeds
• Dizziness
• Faintness or lightheadedness when getting up suddenly from a lying or sitting position
• High level of uric acid in your blood
• Severe pain and swelling in your joints – these are signs of gout
• Bruising
• Headache
• Diarrhoea
• Indigestion
• Constipation
• Bleeding after surgery or from cuts (for example, while shaving) and wounds more than is normal
• Bleeding from your stomach lining (ulcer)
• Bleeding gums

You should avoid taking Brigrel 60 Tablet if you are allergic to Brigrel 60 Tablet or any active and inactive ingredients present in it.  Let your doctor know if you have a medical condition that causes bleeding such as hemophilia, stomach ulcer, or bleeding in your head or bowel. Caution is required before giving Brigrel 60 Tablet to the kidney or liver problems patients. People affected with respiratory problems like asthma, nasal polyps, or rhinitis should consult a doctor before intake of Brigrel 60 Tablet . Brigrel 60 Tablet is not recommended for the breastfeeding mother as it passes into the breast milk. The safety and effectiveness in children less than 18 years of age have not been established, so Brigrel 60 Tablet should not be given to them.

Drug-Drug Interactions: Brigrel 60 Tablet interact with medicines to thin the blood or prevent blood clots (aspirin, warfarin), pain relievers (ibuprofen), antidepressants (citalopram, nefazodone), antibiotics (clarithromycin, rifampicin), to treat HIV infection and AIDS (ritonavir, atazanavir), anti-epileptic (phenytoin, carbamazepine), medicines used to lower cholesterol (simvastatin), medicine for heart problems(digoxin).

Drug-Food Interactions: Brigrel 60 Tablet interacts with grapefruit, drinking grapefruit juice while taking Brigrel 60 Tablet can increase the side effects of Brigrel 60 Tablet . Brigrel 60 Tablet may also interact with St John's wort plant (used for depression) and Ginkgo biloba and increase bleeding risk.

Drug-Disease Interactions: Brigrel 60 Tablet should not be given to people with stomach ulcers, haemophilia (a bleeding disorder), haemorrhage (bleeding in your brain), and kidney or liver problems.

• WARFARIN
• IBUPROFEN
• CITALOPRAM
• CLARITHROMYCIN
• RIFAMPICIN
• PHENYTOIN
• CARBAMAZEPINE
• SIMVASTATIN
• DIGOXIN
• ASPIRIN
• NEFAZODONE
• RITONAVIR
• ATAZANAVIR

• Reducing weight and having a healthy BMI is very important in enhancing cardiac health.

• 30 minutes of daily physical exercise can go a long way in preventing heart disease.

• Avoid smoking to improve cardiac health.

• Invest in a healthy, balanced diet. Avoid fatty foods, keep your cholesterol in check and load up on the green leafy vegetables, fish, lean meats, nuts and dry fruits. 

• Reducing stress is very important in keeping a healthy heart. Try yoga and meditation for a relaxed state of mind.

• Take Brigrel 60 Tablet exactly as prescribed. 

• Talk to your physician if you miss a dose of Brigrel 60 Tablet . Never take a double dose. 

• Do not discontinue taking Brigrel 60 Tablet abruptly or without the physician's advice.

• Please know that your doctor may order blood tests to check your hormone levels while you are on Brigrel 60 Tablet . 

• Your doctor may order a D-dimer to check your clotting profile while on Brigrel 60 Tablet .

• Your doctor may order liver function tests (LFT’s) and a complete blood picture (CBP) to ascertain the effects of Brigrel 60 Tablet .

Blood clot: Blood clot is an aggregation of blood that changes from a liquid to a gel-like state. Clotting is a natural process that prevents you from losing too much blood in surgery or cut, accident, and trauma. When a clot forms inside the veins, it won't always dissolve independently and can become an even life-threatening situation.

Heart attack: Heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of fat, cholesterol, and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). During a heart attack (myocardial infarction), the blood supply which nourishes the heart with oxygen is cut off. This causes the heart muscle to die. A heart attack signs include chest pain, upper body pain, sweating, nausea, fatigue, and trouble breathing.

Stroke: When our brain does not get sufficient oxygen and blood supply, it starts dying within a few minutes leading to a heart attack or stroke.

Acute coronary syndrome: Acute coronary syndrome is most often caused by plaque rupture or clot formation in the heart's arteries. The symptoms may include heart attack-like chest pressure, chest pressure while resting or doing light activity, or sudden heart stoppage.