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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
XAMDEX 100MCG/ML INJECTION 2ML belongs to the class of sedative and hypnotic medicines used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. This medicine works by inhibiting the release of norepinephrine and subsequently blocks pain signals. Common side effects include slow heart rate, a change in blood pressure and an alteration in breathing pattern.
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Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About XAMDEX 100MCG/ML INJECTION 2ML

XAMDEX 100MCG/ML INJECTION 2ML belongs to the group of sedatives used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. Sedation is defined as a state of relaxation, drowsiness or sleep.

XAMDEX 100MCG/ML INJECTION 2ML contains Dexmedetomidine which works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals. Hence XAMDEX 100MCG/ML INJECTION 2ML brings on a sense of relaxation and numbness through massive pain relief. 

XAMDEX 100MCG/ML INJECTION 2ML will be administered by a healthcare professional. Do not self-administer. XAMDEX 100MCG/ML INJECTION 2ML may cause certain common side effects such as a slow heart rate, a change in blood pressure and an alteration in breathing pattern. You are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components of XAMDEX 100MCG/ML INJECTION 2ML. Consult your doctor if you are pregnant, planning to get pregnant or if you are breastfeeding, as XAMDEX 100MCG/ML INJECTION 2ML should be used with caution in these states. Avoid driving or operating machinery as XAMDEX 100MCG/ML INJECTION 2ML causes sedation. Consult your doctor before consuming alcohol with XAMDEX 100MCG/ML INJECTION 2ML.

Uses of XAMDEX 100MCG/ML INJECTION 2ML

Used for Sedation

Directions for Use

XAMDEX 100MCG/ML INJECTION 2ML will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

XAMDEX 100MCG/ML INJECTION 2ML is a sedative that is used for the purpose of sedation in acute settings such as the intensive care unit (ICU). XAMDEX 100MCG/ML INJECTION 2ML finds application in aiding anaesthesia before surgical procedures and is also used to relax patients on mechanical ventilation. XAMDEX 100MCG/ML INJECTION 2ML contains Dexmedetomidine. XAMDEX 100MCG/ML INJECTION 2ML blocks pain signals, so the brain doesn't perceive pain or sensation and hence, brings on a sense of numbness and anaesthesia.

How XAMDEX 100MCG/ML INJECTION 2ML Works

XAMDEX 100MCG/ML INJECTION 2ML contains Dexmedetomidine which works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals. Hence XAMDEX 100MCG/ML INJECTION 2ML brings on a sense of relaxation and numbness through massive pain relief.

Storage

Store in a cool and dry place away from sunlight

Side Effects of XAMDEX 100MCG/ML INJECTION 2ML

  • Change in breathing pattern
  • Slow pulse
  • Fall in blood pressure

What if I have taken an overdose of XAMDEX 100MCG/ML INJECTION 2ML

Since XAMDEX 100MCG/ML INJECTION 2ML is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of XAMDEX 100MCG/ML INJECTION 2ML. Keep your doctor informed if you suffer from any bleeding disorders, disorders of heart rhythm, hypotension (very low blood pressure), stroke, cardiovascular disorders, neurological problems or liver disease. Consult your doctor before taking alcohol with XAMDEX 100MCG/ML INJECTION 2ML. Inform the doctor if you are on anticoagulant (blood-thinner) therapy, sedatives, anaesthetics or any pain killers. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding as XAMDEX 100MCG/ML INJECTION 2ML should be used with caution in these states.

Drug-Drug Interactions

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DexmedetomidineTizanidine
Severe

Drug-Drug Interactions

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DexmedetomidineTizanidine
Severe
How does the drug interact with XAMDEX 100MCG/ML INJECTION 2ML:
Combining Tizanidine and XAMDEX 100MCG/ML INJECTION 2ML can increase the risk of low blood pressure.

How to manage the interaction:
Taking Tizanidine and XAMDEX 100MCG/ML INJECTION 2ML together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, palpitations, chest pain, or excessive sweating, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Invest in a balanced diet. Load up on lean meats, fruits, green leafy vegetables, nuts, oily fish etc. 
  • Cut back on alcohol as this can have an adverse effect on pain states as well as the quality of your sleep.
  • Try meditation and deep breathing to reduce overall stress and pain. 
  • Stop smoking as smoking is known to worsen pain conditions. 
  • Engage in mild physical exercise daily and keep your body active. 

Habit Forming

No

Therapeutic Class

SEDATIVES AND HYPNOTICS

XAMDEX 100MCG/ML INJECTION 2ML Substitute

Substitutes safety advice
  • DEXEM AMPULE INJECTION 0.5ML

    350.10per tablet
  • XAMDEX 100MCG INJECTION

    738.90per tablet
  • Dexmedine 100mcg/1ml Injection

    by AYUR

    452.30per tablet
  • Dexmedine Injection 0.5ml

    by AYUR

    238.10per tablet
  • Dexit 200 Injection 2 ml

    400.50per tablet
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Alcohol

Unsafe

There can be a reaction of alcohol with XAMDEX 100MCG/ML INJECTION 2ML. Use of XAMDEX 100MCG/ML INJECTION 2ML with alcohol is hence not recommended. Please consult your doctor if you have any concerns.

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Pregnancy

Caution

XAMDEX 100MCG/ML INJECTION 2ML should be used with caution during pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Caution

XAMDEX 100MCG/ML INJECTION 2ML should be used with caution during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Unsafe

XAMDEX 100MCG/ML INJECTION 2ML is used only in hospitalised patients. Avoid driving or operating machinery as XAMDEX 100MCG/ML INJECTION 2ML causes sedation.

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Liver

Caution

Exercise caution before using XAMDEX 100MCG/ML INJECTION 2ML in case of liver conditions. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using XAMDEX 100MCG/ML INJECTION 2ML in case of kidney problems. Please consult your doctor to address any concerns.

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Children

Unsafe

XAMDEX 100MCG/ML INJECTION 2ML is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

FAQs

XAMDEX 100MCG/ML INJECTION 2ML belongs to the group of sedatives used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. Sedation is defined as a state of relaxation, drowsiness or sleep.
XAMDEX 100MCG/ML INJECTION 2ML works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals.
Inform your doctor if you have high blood pressure or if you are taking blood pressure-lowering medicines as XAMDEX 100MCG/ML INJECTION 2ML may cause alterations in blood pressure.
XAMDEX 100MCG/ML INJECTION 2ML is not recommended for people with heart rhythm problems, and very low blood pressure that does not respond to treatment. Inform your doctor if you have heart problems, abnormally slow heart rate, or high/low blood pressure.
XAMDEX 100MCG/ML INJECTION 2ML may cause a slow heart rate. Inform your doctor if you have an abnormally slow heart rate as XAMDEX 100MCG/ML INJECTION 2ML may increase the risk of cardiac arrest.
No, XAMDEX 100MCG/ML INJECTION 2ML is not a controlled substance. It is a sedative for patients in acute settings such as the ICU, during surgical procedures, and in those who require a mechanical ventilator.
Yes, XAMDEX 100MCG/ML INJECTION 2ML is approved by the FDA in the year 1999.
In rare cases, XAMDEX 100MCG/ML INJECTION 2ML may cause amnesia in some individuals as it has sedative and hypnotic properties, leading to memory impairment.
The common side effects of XAMDEX 100MCG/ML INJECTION 2ML, which may occur in some individuals, include a slow heart rate, blood pressure changes, and breathing patterns. If these side effects persist, you are advised to consult your doctor.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - XAM0006

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