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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:22 PM IST
Dexdine 100mcg Injection belongs to the class of sedative and hypnotic medicines used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. This medicine works by inhibiting the release of norepinephrine and subsequently blocks pain signals. Common side effects include slow heart rate, a change in blood pressure and an alteration in breathing pattern.
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Prescription drug

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Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Dexdine 100mcg Injection

Dexdine 100mcg Injection belongs to the group of sedatives used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. Sedation is defined as a state of relaxation, drowsiness or sleep.

Dexdine 100mcg Injection contains Dexmedetomidine which works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals. Hence Dexdine 100mcg Injection brings on a sense of relaxation and numbness through massive pain relief. 

Dexdine 100mcg Injection will be administered by a healthcare professional. Do not self-administer. Dexdine 100mcg Injection may cause certain common side effects such as a slow heart rate, a change in blood pressure and an alteration in breathing pattern. You are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components of Dexdine 100mcg Injection. Consult your doctor if you are pregnant, planning to get pregnant or if you are breastfeeding, as Dexdine 100mcg Injection should be used with caution in these states. Avoid driving or operating machinery as Dexdine 100mcg Injection causes sedation. Consult your doctor before consuming alcohol with Dexdine 100mcg Injection.

Uses of Dexdine 100mcg Injection

Used for Sedation

Medicinal Benefits

Dexdine 100mcg Injection is a sedative that is used for the purpose of sedation in acute settings such as the intensive care unit (ICU). Dexdine 100mcg Injection finds application in aiding anaesthesia before surgical procedures and is also used to relax patients on mechanical ventilation. Dexdine 100mcg Injection contains Dexmedetomidine. Dexdine 100mcg Injection blocks pain signals, so the brain doesn't perceive pain or sensation and hence, brings on a sense of numbness and anaesthesia.

Directions for Use

Dexdine 100mcg Injection will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dexdine 100mcg Injection

  • Change in breathing pattern
  • Slow pulse
  • Fall in blood pressure

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of Dexdine 100mcg Injection. Keep your doctor informed if you suffer from any bleeding disorders, disorders of heart rhythm, hypotension (very low blood pressure), stroke, cardiovascular disorders, neurological problems or liver disease. Consult your doctor before taking alcohol with Dexdine 100mcg Injection. Inform the doctor if you are on anticoagulant (blood-thinner) therapy, sedatives, anaesthetics or any pain killers. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding as Dexdine 100mcg Injection should be used with caution in these states.

Drug Interactions

Drug-Drug Interactions: Dexdine 100mcg Injection may interact with sedatives (midazolam, propofol), opioid analgesics (morphine, codeine), and anaesthetics (sevoflurane, isoflurane).

Drug-Food Interactions: Dexdine 100mcg Injection may interact with alcohol.

Drug-Disease Interactions: Dexdine 100mcg Injection should be used with caution in patients with heart rhythm disorder, low blood pressure, stroke, abnormally slow heart rate, low blood volume, neurological disorder, and severe liver problems.

Drug-Drug Interactions Checker List

  • MIDAZOLAM
  • PROPOFOL
  • MORPHINE
  • CODEINE
  • SEVOFLURANE
  • ISOFLURANE

Habit Forming

No

Diet & Lifestyle Advise

  • Invest in a balanced diet. Load up on lean meats, fruits, green leafy vegetables, nuts, oily fish etc. 
  • Cut back on alcohol as this can have an adverse effect on pain states as well as the quality of your sleep.
  • Try meditation and deep breathing to reduce overall stress and pain. 
  • Stop smoking as smoking is known to worsen pain conditions. 
  • Engage in mild physical exercise daily and keep your body active. 

Special Advise

  • You will need to be monitored consistently after receiving Dexdine 100mcg Injection.
  • Elderly people over the age of 65 may require dose adjustments. Discuss with your treating doctor in case of advanced age.
  • Caution should be exercised before administering Dexdine 100mcg Injection with other vasodilatory drugs. 

Disease/Condition Glossary

Sedation: A state of sleep, relaxation or drowsiness brought on by an external substance such as a drug. Sedation is the alleviation of irritation, anxiety or agitation by administering a sedative drug. It is generally carried out to ease the process of a diagnostic procedure or surgery. 

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Alcohol

Unsafe

There can be a reaction of alcohol with Dexdine 100mcg Injection. Use of Dexdine 100mcg Injection with alcohol is hence not recommended. Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Dexdine 100mcg Injection should be used with caution during pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Caution

Dexdine 100mcg Injection should be used with caution during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Unsafe

Dexdine 100mcg Injection is used only in hospitalised patients. Avoid driving or operating machinery as Dexdine 100mcg Injection causes sedation.

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Liver

Caution

Exercise caution before using Dexdine 100mcg Injection in case of liver conditions. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Dexdine 100mcg Injection in case of kidney problems. Please consult your doctor to address any concerns.

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Children

Unsafe

Dexdine 100mcg Injection is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

Country of origin

India
Other Info - DE74896

Author Details

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FAQs

Dexdine 100mcg Injection belongs to the group of sedatives used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. Sedation is defined as a state of relaxation, drowsiness or sleep.
Dexdine 100mcg Injection works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals.
Inform your doctor if you have high blood pressure or if you are taking blood pressure-lowering medicines as Dexdine 100mcg Injection may cause alterations in blood pressure.
Dexdine 100mcg Injection is not recommended for people with heart rhythm problems, and very low blood pressure that does not respond to treatment. Inform your doctor if you have heart problems, abnormally slow heart rate, or high/low blood pressure.
Dexdine 100mcg Injection may cause a slow heart rate. Inform your doctor if you have an abnormally slow heart rate as Dexdine 100mcg Injection may increase the risk of cardiac arrest.
No, Dexdine 100mcg Injection is not a controlled substance. It is a sedative for patients in acute settings such as the ICU, during surgical procedures, and in those who require a mechanical ventilator.
Yes, Dexdine 100mcg Injection is approved by the FDA in the year 1999.
In rare cases, Dexdine 100mcg Injection may cause amnesia in some individuals as it has sedative and hypnotic properties, leading to memory impairment.
The common side effects of Dexdine 100mcg Injection, which may occur in some individuals, include a slow heart rate, blood pressure changes, and breathing patterns. If these side effects persist, you are advised to consult your doctor.

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