VONAZ INJECTION

VONAZ INJECTION belongs to the class of medicines known as 'antifungals' used to treat a broad range of fungal infections. A fungal infection is caused when a fungus invades and affects any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area and blood.

VONAZ INJECTION contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

VONAZ INJECTION will be administered by a qualified healthcare professional. In some cases, you may experience certain common side effects, such as injection site reactions, peripheral oedema, headache, diarrhoea, vomiting, abdominal pain, chest pain, nausea, fever, anxiety, insomnia, confusion, weakness, tingling sensation, sleepiness, dizziness, irregular heartbeats, low blood pressure, stomach upset, constipation, rashes, itchiness, red skin, back pain and chills. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking VONAZ INJECTION, let your doctor know about your medical condition, sensitivities, and medications. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. VONAZ INJECTION may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

VONAZ INJECTION belongs to the class of medicines known as 'antifungal agents', used to treat a broad range of fungal infections, including aspergillosis (a disease caused by Aspergillus), candidiasis (fungal infection caused by yeast), coccidioidomycosis (an infection caused by the fungus Coccidioides), histoplasmosis (an infection caused by a fungus called Histoplasma), and penicilliosis (a disease caused by the fungus Talaromyces marneffei). It also effectively treats CNS fungal infections transmitted by epidural injection of contaminated steroids. On the other hand, it can prevent fungal infections in people undergoing bone marrow transplants. VONAZ INJECTION works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

• Injection site reactions
• Peripheral oedema
• Headache
• Diarrhoea
• Vomiting
• Abdominal pain
• Nausea
• Rashes
• Fever
• Anxiety
• Insomnia
• Confusion
• Weakness
• Tingling sensation
• Sleepiness
• Dizziness
• Irregular heartbeats
• Low blood pressure
• Stomach upset
• Constipation
• Jaundice
• Hair loss
• Flaky skin
• Itchiness
• Red skin
• Back pain
• Chest pain
• Chills

Inform your doctor about your medical conditions, sensitivities, and medications you are using. And also, let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding. Women of childbearing potential should always use effective contraception during treatment. Please inform your doctor if you are suffering from a heart problem like an irregular heartbeat, slow heart rate or abnormality in ECG (electrocardiogram), QT prolongation, or if you have hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption. VONAZ INJECTION may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Drug-Drug Interactions: VONAZ INJECTION is known to interact with immunosuppressants (e.g. Sirolimus), antibiotics (e.g. rifampicin, rifabutin) and anticonvulsant medications (e.g. carbamazepine).

Drug-Food Interactions: VONAZ INJECTION is known to interact with St. John's wort (a natural remedy to treat depression). 

Drug-Disease Interactions: VONAZ INJECTION may interact with disease conditions, including cardiac disorders (QT prolongation), hereditary intolerance for galactose (a person lacks the protein needed to break down fructose), Lapp lactase deficiency (hereditary condition; difficult to digest lactose), or glucose-galactose malabsorption (a genetic metabolic disease characterized by impaired glucose-galactose absorption).

• SIROLIMUS
• RIFABUTIN
• CARBAMAZEPINE

• In wet places such as changing rooms and gym showers, don’t walk barefoot to prevent fungal infections.
• Do not scratch the affected skin, as it can spread the infection to other body parts.
• Avoid sharing towels, combs, bedsheets, shoes or socks with others.
• Wash your bedsheets and towels regularly.
• It is advisable to follow a candida diet during fungal infections. This diet excludes sugar, gluten, certain dairy products, and alcohol. Switch to low-sugar fruits, non-starchy vegetables and gluten-free foods. A very-high sugar or high-carbohydrate diet may increase the count of Candida in some people.

• Liver function tests should be monitored regularly while on treatment with VONAZ INJECTION.

Fungal infections: Fungal infection occurs when a fungus enters, infects and multiplies in the body. Fungi can live in water, soil, air and plants. Fungi affect any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area and blood. Mild fungal skin infections are common and can cause rashes. Fungal infections affecting body organs like the lungs can cause flu or tuberculosis. Some fungal diseases like cryptococcal meningitis and blood infections can be fatal. A few common fungal infections are yeast infections that affect the genital area, oesophagus and urinary tract caused by Candida.