Vonatel-Trio Tablet is used to treat hypertension (high blood pressure) and reduce the risk of heart attack or stroke in adults. Hypertension is a condition in which the force of blood against the artery walls is very high. It will be an addition to the workload of the heart and arteries.

Vonatel-Trio Tablet is a combination of three drugs, namely: Chlorthalidone (diuretic), Cilnidipine (calcium channel blocker), and Telmisartan (angiotensin II receptor blocker). Chlorthalidone belongs to the class of diuretics (water tablets) that work by increasing the removal of excess water and certain salts, such as sodium and potassium, from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Cilnidipine is a calcium channel blocker that acts on muscle cells in the artery walls and relaxes muscle cells. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. Telmisartan works by blocking a hormone called angiotensin II in the body that causes the narrowing of blood vessels leading to high blood pressure. Thereby, Vonatel-Trio Tablet widens and relaxes blood vessels. Thus, it lowers high blood pressure.

Take Vonatel-Trio Tablet as prescribed by your doctor. You are advised to take Vonatel-Trio Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, headache, low blood pressure, stomach upset, or tiredness. Most of these side effects of Vonatel-Trio Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Vonatel-Trio Tablet or any other medicines, please tell your doctor. Vonatel-Trio Tablet is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, avoid taking Vonatel-Trio Tablet and consult a doctor. If you are about to take anesthesia or undergo any surgery, you are advised to inform your doctor that you are taking Vonatel-Trio Tablet . Drive only if you are alert, as Vonatel-Trio Tablet may cause dizziness or tiredness. You are recommended to avoid alcohol consumption with Vonatel-Trio Tablet as it may increase the risk of low blood pressure.

Vonatel-Trio Tablet contains Chlorthalidone, Cilnidipine, and Telmisartan used to treat high blood pressure. Chlorthalidone is a diuretic (water tablet) that increases the removal of excess water and certain salts, such as sodium and potassium, from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Cilnidipine and Telmisartan relax and widen blood vessels. Thus, Vonatel-Trio Tablet lowers high blood pressure and reduces the risk of stroke, heart attack, or other heart problems.

• Dizziness
• Headache
• Low blood pressure
• Stomach upset
• Tiredness
• Tachycardia
• Ankle Swelling
• Flushing
• Loss of appetite
• Change in blood glucose levels
• Gastric Irritation

If you are allergic to Vonatel-Trio Tablet or any other medicines, please tell your doctor. Vonatel-Trio Tablet is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, avoid taking Vonatel-Trio Tablet and consult a doctor. If you are about to take anesthesia or undergo any surgery, you are advised to inform your doctor that you are taking Vonatel-Trio Tablet . Avoid taking Vonatel-Trio Tablet if you have low levels of sodium or potassium in the blood, gout, kidney stones, Addison’s disease (adrenal gland does not produce sufficient steroids), high blood levels of calcium, or severe liver or kidney problems. Drive only if you are alert as Vonatel-Trio Tablet may cause dizziness or tiredness. You are recommended to avoid alcohol consumption with Vonatel-Trio Tablet as it may increase the risk of low blood pressure.

Drug-Drug Interaction: Vonatel-Trio Tablet may interact with non-steroidal anti-inflammatory drugs (aspirin, ibuprofen), calcium channel blockers (amlodipine), water pills (amiloride, spironolactone), heart-related medicines (quinidine, digoxin), antimanic drug (lithium), antibiotics (erythromycin, rifampicin), anticonvulsant (phenytoin).

Drug-Food Interaction: Avoid taking potassium-rich foods such as bananas, sweet potatoes, nuts, and noni juice with Vonatel-Trio Tablet as it may result in hyperkalemia (high levels of potassium in the blood) and cause severe adverse effects. Also, Vonatel-Trio Tablet may interact with grapefruit juice and increase the levels of Vonatel-Trio Tablet in blood.

Drug-Disease Interaction: Avoid taking Vonatel-Trio Tablet if you have low levels of sodium or potassium in the blood, gout, kidney stones, Addison’s disease (adrenal gland does not produce sufficient steroids), high blood levels of calcium, severe liver or kidney problems. If you have diabetes, high cholesterol, low blood pressure, renal artery stenosis (narrowing of blood vessels to one or both the kidneys), heart, liver, or kidney problems, inform your doctor before taking Vonatel-Trio Tablet .

• ASPIRIN
• IBUPROFEN
• AMLODIPINE
• AMILORIDE
• SPIRONOLACTONE
• QUINIDINE
• DIGOXIN
• LITHIUM
• ERYTHROMYCIN
• RIFAMPICIN
• PHENYTOIN

• Maintain a low-salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.

• Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.

• Chronic stress may also cause high blood pressure. Therefore, avoid stress by changing your expectations, reacting in certain situations, and doing activities that you enjoy by making time for yourself.

• Maintain a diet that is rich in fruits, vegetables, whole grains, and low-fat dairy products.

• Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil which may help in lowering high blood pressure.

• Quit smoking and avoid the consumption of alcohol.

• Monitor your blood pressure regularly, and if you notice any fluctuations, please consult a doctor.

• Your doctor may order regular monitoring of blood glucose and electrolyte levels.

Blood pressure is the measurement of the heart's force to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Normal blood pressure lies between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.