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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:24 PM IST
Vomrab Tablet is used to treat nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori and Zollinger-Ellison syndrome. It contains Rabeprazole and Ondansetron which inhibit the production of acid in the stomach, protect the ulcers from acid, and block the action of serotonin (chemical messenger) that triggers nausea and vomiting. This medicine may sometimes cause side effects such as constipation, headache, fatigue, diarrhoea, sore throat, and abdominal pain.
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Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Vomrab Tablet

Vomrab Tablet is a gastrointestinal medication, primarily used to treat nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, and erosive oesophagitis (acid-related damage to the lining of the oesophagus). Vomrab Tablet is also used to treat infections caused by Helicobacter pylori and Zollinger-Ellison syndrome. GERD is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.

Vomrab Tablet contains two medicines: Rabeprazole and Ondansetron. Rabeprazole belongs to the group of drugs called ‘proton pump inhibitors.’ It blocks the action of the gastric proton pump that is responsible for the production of acid in the stomach. This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers. Ondansetron belongs to the class of anti-emetics (prevents vomiting). It works by blocking the action of serotonin (chemical messenger) that triggers nausea and vomiting.

Take Vomrab Tablet as advised by the doctor. Your doctor will advise the appropriate dose that suits your medical condition. Common side effects of Vomrab Tablet include nausea, vomiting, constipation, headache, fatigue, diarrhoea, sore throat, and abdominal pain. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor’s advice.

Let your doctor know if you are sensitive or allergic to Vomrab Tablet or any other medications. Before using Vomrab Tablet, let your doctor know if you have any liver, kidney or heart diseases, and gastrointestinal problems. Pregnant and breastfeeding women should consult their doctor before using Vomrab Tablet. Avoid alcohol intake while using Vomrab Tablet since it can increase acid production in the stomach. Ondansetron in Vomrab Tablet is not recommended for children below four years of age.

Uses of Vomrab Tablet

Treatment of Nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, erosive oesophagitis, and Zollinger-Ellison syndrome.

Medicinal Benefits

Vomrab Tablet is used to treat nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn and erosive oesophagitis. It contains Rabeprazole and Ondansetron. Rabeprazole is a proton pump inhibitor that blocks the action of the gastric proton pump that is responsible for acid production in the stomach. Ondansetron is an anti-emetic drug. It works by blocking the action of serotonin (chemical messenger) that triggers nausea and vomiting. Thus, collectively Vomrab Tablet prevents nausea and vomiting, reduces the amount of acid produced, heals the ulcers, and prevents new ulcers. Vomrab Tablet is also used to treat infections caused by Helicobacter pylori and Zollinger-Ellison syndrome.

Directions for Use

Swallow Vomrab Tablet as a whole with a glass of water. You can take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Vomrab Tablet

  • Nausea
  • Vomiting
  • Constipation
  • Headache
  • Fatigue
  • Diarrhoea
  • Sore throat
  • Abdominal pain

Drug Warnings

Let your doctor know if you are sensitive to Vomrab Tablet or its components. Vomrab Tablet should be used with caution and only under doctor’s supervision if you have stomach/intestinal problems, liver, kidney or heart diseases, recent abdominal surgery, risk of bone fractures and autoimmune diseases like lupus. Long term treatment with Vomrab Tablet may increase the risk of fractures of the hip, spine, and wrist. Hence, inform your doctor if you have osteoporosis, bone-related problems, or taking any corticosteroids before starting Vomrab Tablet. Let your doctor know if you are pregnant or a nursing mother before starting Vomrab Tablet. Avoid alcohol intake while using Vomrab Tablet since it can increase acid production in the stomach.

Drug Interactions

Drug-Drug Interaction: Vomrab Tablet may interact with pain killers (acetaminophen, ibuprofen), anti-anxiety (pregabalin, diazepam), antiparkinson medicine (apomorphine), anti-depressants (duloxetine), blood thinners (clopidogrel), a drug used to treat hypothyroidism (levothyroxine), anti-HIV (atazanavir), antifungals (ketoconazole), anti-cancer drugs (methotrexate), and vitamins (cyanocobalamin).

Drug-Food Interaction: Avoid fatty foods, alcohol, caffeine, and other triggering foods that can worsen your gastrointestinal problems.

Drug-Disease Interaction: Brief your doctor if you have a medical history of stomach/intestinal problems, liver, kidney or heart diseases, recent abdominal surgery, risk of bone fractures, autoimmune diseases like lupus, and Vitamin B12 deficiency before starting Vomrab Tablet.

Drug-Drug Interactions Checker List

  • ACETAMINOPHEN
  • IBUPROFEN
  • PREGABALIN
  • DIAZEPAM
  • APOMORPHINE
  • DULOXETINE
  • CLOPIDOGREL
  • LEVOTHYROXINE
  • ATAZANAVIR
  • KETOCONAZOLE
  • METHOTREXATE
  • CYANOCOBALAMIN

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Limit taking high fibre foods, foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. 
  • Do not have large meals at a time, instead try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.
  • Practice yoga and recreation techniques to manage your emotional stress.
  • If you are lactose intolerant, avoid using dairy products since it can worsen your stomach discomforts.
  • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
  • Drink plenty of fluids to prevent dehydration.

Special Advise

  • It is advised to monitor your blood pressure and blood glucose levels regularly while using Vomrab Tablet.
  • Your doctor may suggest diagnostic procedures like endoscopy or colonoscopy to understand your disease and its severity.
  • Vomrab Tablet may cause abnormal blood and liver enzyme tests. Inform your doctor and laboratory staff that you are taking Vomrab Tablet before undergoing any examinations.

Disease/Condition Glossary

Gastrointestinal diseases: The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity, GERD, heartburn, stomach ulcer, and Zollinger Ellison syndrome. Gastroesophageal reflux disease (GERD) is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers. 

Nausea/Vomiting: Nausea is an uneasy feeling in the stomach in which a person feels a strong urge to vomit. Vomiting is a natural response of the body in which a person wants to expel stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain, or irritation to the stomach.

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Alcohol

Unsafe

Alcohol consumption may increase acid production in the stomach. It is advised to avoid alcohol intake to prevent any undesirable side effects of Vomrab Tablet and further worsening of your disease. Please consult your doctor for more information before using Vomrab Tablet.

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Pregnancy

Caution

Vomrab Tablet is not recommended for use in pregnancy since Ondansetron may cause harmful effects on the developing baby. It is advised to consult your doctor if you plan to conceive or already pregnant before starting Vomrab Tablet.

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Breast Feeding

Caution

It is not known if Vomrab Tablet passes into breast milk. Please consult your doctor before taking Vomrab Tablet if you are a nursing mother.

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Driving

Safe if prescribed

Vomrab Tablet is probably safe to use and doesn’t affect driving. However, please do not drive or operate machines if you experience any side effects that affect your ability to drive.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Vomrab Tablet.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Vomrab Tablet.

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Children

Caution

Ondansetron in Vomrab Tablet may not be suitable for children below four years of age. Please consult your doctor before giving Vomrab Tablet to your child. Your doctor will decide the dose and duration based on your child’s age and medical condition.

Country of origin

India

Manufacturer/Marketer address

p - 145, block - a, bangur avenue kolkata - 700055, west bengal, india
Other Info - VO14860

FAQs

Vomrab Tablet is used to treat nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, and erosive oesophagitis (acid-related damage to the lining of the oesophagus). It is also used to treat infections caused by Helicobacter pylori and Zollinger-Ellison syndrome.
Vomrab Tablet works by reducing the amount of acid produced in the stomach and blocks the action of certain chemical messengers that trigger nausea and vomiting. Thus, Vomrab Tablet relieves stomach ulcers, heartburn, GERD, nausea, vomiting and other gastrointestinal discomforts.
Vomrab Tablet should be used with caution and only under doctor’s supervision if you have any liver, kidney or heart diseases, stomach and intestinal problems, recent abdominal surgery, Vitamin B12 deficiency, risk of bone fractures and autoimmune diseases like lupus.
Talk to your doctor if you do not feel better even after taking Vomrab Tablet for 14 days. Do not take Vomrab Tablet for longer durations unless prescribed by the doctor. If Vomrab Tablet is prescribed for longer durations, a regular check-up is advised.
Antacids do not interfere with the absorption of Vomrab Tablet. However, it is advised to take antacid and Vomrab Tablet at different times. Please seek medical advice on how to use other medicines like antacids while using Vomrab Tablet.
Diarrhoea might be a side-effect of Vomrab Tablet. Drink lots of fluids and eat foods rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Prolonged intake of Vomrab Tablet is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.
On long term treatment, Rabeprazole in Vomrab Tablet may increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis, bone-related problems, or taking any corticosteroids. Your doctor may suggest supplements like Calcium citrate and Vitamin D.
Rabeprazole in Vomrab Tablet may cause low Vitamin B12 levels on long term usage. Your doctor may adjust the dose of Vomrab Tablet accordingly and may also suggest Vitamin B12 supplements.
Vomrab Tablet weakens bones and can increase the risk of fractures in elderly patients if used for long term or if taken in high doses.
Long term usage of the Vomrab Tablet causes disturbances in liver function, B12 deficiency and changes in electrolyte (magnesium, calcium and sodium) levels. Therefore, if you experience symptoms such as yellow skin and eyes, nausea, dizziness, loss of appetite, fits, headache, itching, tiredness, pale skin, or irritability, consult your doctor immediately. Your doctor may recommend frequent follow-ups and blood tests if Vomrab Tablet is prescribed for long term use.
Yes, you can take Vomrab Tablet on an empty stomach preferably in the morning for better acid regulation throughout the day or take it as advised by your doctor. But try to take it at the same time every day for best results.
Vomrab Tablet starts working within 60 minutes of taking it and takes about 2 to 4 hours to show full benefit. Although it may take up to 4 weeks to relieve your symptoms considerably, you should begin to feel better within 2 to 3 days. If you have concerns, discuss with your doctor.
You are recommended not to stop taking Vomrab Tablet on your own without first consulting your doctor as it may worsen your condition. If you experience any difficulty while using Vomrab Tablet, please consult your doctor.
Vomrab Tablet is used along with antibiotics for the treatment of H. Pylori infection. It reduces the stomach acid volume and decreases breakdown and washout of antibiotics resulting in increased antibiotic concentration and tissue penetration. Also, it helps in symptomatic relief by reducing associated heartburn, acidity, and reflux.
Yes, you can take Vomrab Tablet with vitamin D. It is usually advised to take vitamin D as a supplement with Vomrab Tablet as the long-term use of Vomrab Tablet reduces calcium absorption and may result in calcium deficiency. This can further lead to osteoporosis (thinning of bones) and increase the risk of bone fractures like wrist, spine and hip fractures. Please discuss with your doctor about ways to prevent this.
Long-term usage of Vomrab Tablet can decrease magnesium levels in patients taking several daily doses for 3 months or longer. Check your magnesium levels at regular intervals. However, if you experience dizziness, seizures (fits), abnormal or fast heartbeat, jerking movements or shaking (tremors), jitteriness, muscle weakness, spasms of the hands and feet, cramps, or muscle pains, inform your doctor.
No, you are recommended not to take alcohol with Vomrab Tablet as it may increase acid production in the stomach and worsening of your symptoms. If you still have any concerns, please discuss with your doctor.
It is advised to take Vomrab Tablet 1 hour before a meal. Avoid spicy and fatty foods while taking Vomrab Tablet. Also, cut down on caffeinated drinks such as coffee, tea, and cola. Alcohol consumption should also be avoided as it may worsen your symptoms.
Eat healthy and exercise regularly. You can consult a dietician to obtain a diet plan that works best for you. Eat at least 3 hours before going to bed to reduce the chances of worsening of your symptoms at night. Avoid spicy and fatty foods and caffeinated drinks such as coffee, tea, and cola. Also, avoid smoking and alcohol consumption as they may worsen your symptoms.
The side effects of Vomrab Tablet include headache, nausea, vomiting, constipation, diarrhoea, fatigue, sore throat and stomach pain. If any of these side effects persist or worsen, please consult your doctor.

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