Rafron Total Tablet is a gastrointestinal medication, primarily used to treat nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, and erosive oesophagitis (acid-related damage to the lining of the oesophagus). Rafron Total Tablet is also used to treat infections caused by Helicobacter pylori and Zollinger-Ellison syndrome. GERD is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.

Rafron Total Tablet contains two medicines: Rabeprazole and Ondansetron. Rabeprazole belongs to the group of drugs called ‘proton pump inhibitors.’ It blocks the action of the gastric proton pump that is responsible for the production of acid in the stomach. This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers. Ondansetron belongs to the class of anti-emetics (prevents vomiting). It works by blocking the action of serotonin (chemical messenger) that triggers nausea and vomiting.

Take Rafron Total Tablet as advised by the doctor. Your doctor will advise the appropriate dose that suits your medical condition. Common side effects of Rafron Total Tablet include nausea, vomiting, constipation, headache, fatigue, diarrhoea, sore throat, and abdominal pain. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor’s advice.

Let your doctor know if you are sensitive or allergic to Rafron Total Tablet or any other medications. Before using Rafron Total Tablet , let your doctor know if you have any liver, kidney or heart diseases, and gastrointestinal problems. Pregnant and breastfeeding women should consult their doctor before using Rafron Total Tablet . Avoid alcohol intake while using Rafron Total Tablet since it can increase acid production in the stomach. Ondansetron in Rafron Total Tablet is not recommended for children below four years of age.

Rafron Total Tablet is used to treat nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn and erosive oesophagitis. It contains Rabeprazole and Ondansetron. Rabeprazole is a proton pump inhibitor that blocks the action of the gastric proton pump that is responsible for acid production in the stomach. Ondansetron is an anti-emetic drug. It works by blocking the action of serotonin (chemical messenger) that triggers nausea and vomiting. Thus, collectively Rafron Total Tablet prevents nausea and vomiting, reduces the amount of acid produced, heals the ulcers, and prevents new ulcers. Rafron Total Tablet is also used to treat infections caused by Helicobacter pylori and Zollinger-Ellison syndrome.

• Nausea
• Vomiting
• Constipation
• Headache
• Fatigue
• Diarrhoea
• Sore throat
• Abdominal pain

Let your doctor know if you are sensitive to Rafron Total Tablet or its components. Rafron Total Tablet should be used with caution and only under doctor’s supervision if you have stomach/intestinal problems, liver, kidney or heart diseases, recent abdominal surgery, risk of bone fractures and autoimmune diseases like lupus. Long term treatment with Rafron Total Tablet may increase the risk of fractures of the hip, spine, and wrist. Hence, inform your doctor if you have osteoporosis, bone-related problems, or taking any corticosteroids before starting Rafron Total Tablet . Let your doctor know if you are pregnant or a nursing mother before starting Rafron Total Tablet . Avoid alcohol intake while using Rafron Total Tablet since it can increase acid production in the stomach.

Drug-Drug Interaction: Rafron Total Tablet may interact with pain killers (acetaminophen, ibuprofen), anti-anxiety (pregabalin, diazepam), antiparkinson medicine (apomorphine), anti-depressants (duloxetine), blood thinners (clopidogrel), a drug used to treat hypothyroidism (levothyroxine), anti-HIV (atazanavir), antifungals (ketoconazole), anti-cancer drugs (methotrexate), and vitamins (cyanocobalamin).

Drug-Food Interaction: Avoid fatty foods, alcohol, caffeine, and other triggering foods that can worsen your gastrointestinal problems.

Drug-Disease Interaction: Brief your doctor if you have a medical history of stomach/intestinal problems, liver, kidney or heart diseases, recent abdominal surgery, risk of bone fractures, autoimmune diseases like lupus, and Vitamin B12 deficiency before starting Rafron Total Tablet .

• ACETAMINOPHEN
• IBUPROFEN
• PREGABALIN
• DIAZEPAM
• APOMORPHINE
• DULOXETINE
• CLOPIDOGREL
• LEVOTHYROXINE
• ATAZANAVIR
• KETOCONAZOLE
• METHOTREXATE
• CYANOCOBALAMIN

• Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
• Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
• Limit taking high fibre foods, foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. 
• Do not have large meals at a time, instead try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.
• Practice yoga and recreation techniques to manage your emotional stress.
• If you are lactose intolerant, avoid using dairy products since it can worsen your stomach discomforts.
• If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
• Drink plenty of fluids to prevent dehydration.

• It is advised to monitor your blood pressure and blood glucose levels regularly while using Rafron Total Tablet .
• Your doctor may suggest diagnostic procedures like endoscopy or colonoscopy to understand your disease and its severity.
• Rafron Total Tablet may cause abnormal blood and liver enzyme tests. Inform your doctor and laboratory staff that you are taking Rafron Total Tablet before undergoing any examinations.

Gastrointestinal diseases: The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity, GERD, heartburn, stomach ulcer, and Zollinger Ellison syndrome. Gastroesophageal reflux disease (GERD) is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers. 

Nausea/Vomiting: Nausea is an uneasy feeling in the stomach in which a person feels a strong urge to vomit. Vomiting is a natural response of the body in which a person wants to expel stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain, or irritation to the stomach.