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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Vasopar 1Ml Inj is used in the treatment of Low blood pressure (in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines), Diabetes insipidus and to Control bleeding from esophageal varices. It contains Vasopressin, a human-made form of Vasopressin. When your body cannot produce enough Vasopressin, Vasopar 1Ml Inj is used to replace it. It also helps treat diabetes insipidus by increasing the amount of water reabsorption from the kidneys. It helps to control bleeding from esophagal varices by increasing plasma levels of factor VIII activity in patients with bleeding disorders.

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Composition :

VASOPRESSIN-20IU

Manufacturer/Marketer :

AAA Pharma Trade Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Vasopar 1Ml Inj

Vasopar 1Ml Inj belongs to the class of antidiuretic hormones. It is used to treat diabetes insipidus and to control bleeding from esophagal varices. It can also be used to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines. Diabetes insipidus is a rare form of diabetes, causing the production of large quantities of urine.

Vasopar 1Ml Inj contains Vasopressin, a human-made form of Vasopressin (antidiuretic hormone). When your body cannot produce enough Vasopressin, Vasopar 1Ml Inj is used to replace it. It also helps treat diabetes insipidus (a rare form of diabetes causing the production of large quantities of urine) by increasing the amount of water reabsorption from the kidneys. Vasopar 1Ml Inj helps to control bleeding from esophagal varices by increasing plasma levels of factor VIII activity in patients with bleeding disorders. Besides this, Vasopressin causes vasoconstriction by binding to V1 receptors on vascular smooth muscle. Thus, Vasopressin helps to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.

Vasopar 1Ml Inj will be administered by a healthcare professional; do not self-administer. The common side effects of Vasopar 1Ml Inj include nausea, vomiting, fatigue, fast or irregular heart rate, hyponatremia (low blood sodium levels), ischemia (restriction in blood supply), and redness/pain/swelling at the injection site. These side effects may not occur in everyone using this medication and gradually resolve over time. If the side effects persist longer or worsen, please seek a doctor's advice.

Before starting Vasopar 1Ml Inj, let your doctor know if you have any medical history of kidney impairment, cerebral vascular disorder, peripheral arterial disease, ischemic heart disease, congestive heart failure, seizures, asthma, fluid retention, or migraine. While using Vasopar 1Ml Inj, avoid drinking large amounts of fluid, including alcohol, since it could lead to the build-up of water in the body. Inform your doctor if you are pregnant or breastfeeding. Vasopar 1Ml Inj can cause water intoxication characterised by drowsiness, being uninterested in anything (listless) and headaches. If you notice any of these signs, seek immediate medical help. If it is not corrected, water intoxication can lead to fits or even coma.

Uses of Vasopar 1Ml Inj

Treatment of Low blood pressure (in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines), Diabetes insipidus and to Control bleeding from esophageal varices

Directions for Use

A healthcare professional will administer it; do not self-administer.

Medicinal Benefits

Vasopar 1Ml Inj contains Vasopressin, an antidiuretic (that controls fluid balance) hormone synthesized in the hypothalamus of the pituitary gland. When your body cannot produce enough Vasopressin, Vasopar 1Ml Inj is used to replace it. It helps treat diabetes insipidus. (a rare form of diabetes causing the production of large quantities of urine). Vasopressin increases the amount of water absorbed back into your kidneys. Thus, it helps treat diabetes insipidus. Vasopar 1Ml Inj increases plasma levels of factor VIII activity in patients with bleeding disorders. Thus, it helps to control bleeding from esophageal varices. Besides this, Vasopressin causes vasoconstriction by binding to V1 receptors on vascular smooth muscle. Thus, Vasopressin helps to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.

How Vasopar 1Ml Inj Works

Vasopar 1Ml Inj contains Vasopressin, a human-made form of Vasopressin (antidiuretic hormone). When your body cannot produce enough Vasopressin, Vasopar 1Ml Inj is used to replace it. It also helps treat diabetes insipidus (a rare form of diabetes causing the production of large quantities of urine) by increasing the amount of water reabsorption from the kidneys. Vasopar 1Ml Inj helps to control bleeding from esophagal varices by increasing plasma levels of factor VIII activity in patients with bleeding disorders. Besides this, Vasopressin causes vasoconstriction by binding to V1 receptors on vascular smooth muscle. Thus, Vasopressin helps to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Vasopar 1Ml Inj

  • Nausea
  • Vomiting
  • Fatigue
  • Fast or irregular heart rate
  • Hyponatremia (low blood sodium levels)
  • Ischemia (restriction in blood supply)
  • Redness/pain/swelling at the injection site

What if I have taken an overdose of Vasopar 1Ml Inj

As Vasopar 1Ml Inj is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly

Drug Warnings

It is recommended not to use if you are allergic to vasopressin or any of the other ingredients present in Vasopar 1Ml Inj or suffer from any diseases or conditions associated with your blood vessels, especially the blood vessels of your heart, suffer from a certain type of kidney disease called chronic nephritis with nitrogen retention (your doctor will advise you) or if you are intended to receive halogenated anaesthetic agents during surgical procedures. Caution and regular monitoring are essential while using Vasopar 1Ml Inj if you have asthma, allergic conditions, migraine, epilepsy (fits), high blood pressure, heart or kidney disease, obstruction of the blood vessels of the heart, or undergone removal of the pituitary gland. So, before taking the Vasopar 1Ml Inj, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. It may cause maternal adverse reactions like tonic uterine contractions. 

Drug-Drug Interactions

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Vasopressin (argipressin)Ziprasidone
Critical
Vasopressin (argipressin)Chloroquine
Severe

Drug-Drug Interactions

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Vasopressin (argipressin)Ziprasidone
Critical
How does the drug interact with Vasopar 1Ml Inj:
Co-administration of Ziprasidone together with Vasopressin can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Ziprasidone with Vasopar 1Ml Inj together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Vasopressin (argipressin)Chloroquine
Severe
How does the drug interact with Vasopar 1Ml Inj:
Using chloroquine together with vasopressin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and vasopressin together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Vasopressin (argipressin)Hydroxychloroquine
Severe
How does the drug interact with Vasopar 1Ml Inj:
The combined use of vasopressin and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of vasopressin and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Vasopressin (argipressin)Ceritinib
Severe
How does the drug interact with Vasopar 1Ml Inj:
Taking Vasopressin with Ceritinib may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Ceritinib and Vasopar 1Ml Inj together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations make sure to contact a doctor. Do not discontinue any medications without consulting a doctor.
Vasopressin (argipressin)Amisulpride
Severe
How does the drug interact with Vasopar 1Ml Inj:
Using amisulpride together with vasopressin can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Amisulpride and Vasopar 1Ml Inj can cause an interaction, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Vasopressin (argipressin)Gatifloxacin
Severe
How does the drug interact with Vasopar 1Ml Inj:
Taking Gatifloxacin and Vasopressin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin and Vasopressin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Vasopressin (argipressin)Disopyramide
Severe
How does the drug interact with Vasopar 1Ml Inj:
The combined use of Vasopressin and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Vasopressin and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Vasopressin (argipressin)Moxifloxacin
Severe
How does the drug interact with Vasopar 1Ml Inj:
Using moxifloxacin together with vasopressin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Moxifloxacin and Vasopar 1Ml Inj, you can take these medicines together if prescribed by your doctor. It's important to keep an eye on your qt interval. If you have to use it at the same time as something else, make sure to be careful and have regular check-ups with your doctor. Do not stop using any medications without first talking to your doctor.
Vasopressin (argipressin)Mifepristone
Severe
How does the drug interact with Vasopar 1Ml Inj:
Co-administration of vasopressin with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking vasopressin with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
Vasopressin (argipressin)Sotalol
Severe
How does the drug interact with Vasopar 1Ml Inj:
Using sotalol together with Vasopar 1Ml Inj can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Vasopar 1Ml Inj, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Reduce the amount of salt and protein in your diet, which will help your kidneys to produce less urine.
  • Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime since it can lead to increased urination. 
  • Avoid activities that cause dehydration, such as excessive physical exercise or spending time in the heat.
  • Optimal water intake is recommended to prevent dehydration due to excessive urination.

Habit Forming

No

Therapeutic Class

HORMONES

Vasopar 1Ml Inj Substitute

Substitutes safety advice
  • Cpressin P Injection 1 ml

    217.80per tablet
  • VPRESS 20IU INJECTION 1ML

    449.00per tablet
  • Vascel 20IU Injection 1 ml

    256.50per tablet
  • Vasmed Injection 1 ml

    273.60per tablet
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Alcohol

Caution

Avoid consuming alcohol while on treatment with Vasopar 1Ml Inj.

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Pregnancy

Caution

The safety of Vasopar 1Ml Inj in pregnant women is unknown. Therefore, please inform your doctor if you are pregnant or expecting pregnancy; your doctor will weigh the benefits and potential risks before prescribing this medicine.

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Breast Feeding

Caution

Inform your doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the treatment to the mother.

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Driving

Caution

Vasopar 1Ml Inj usually does not interfere with your driving ability. Do not drive or operate machinery if you experience unmanageable side effects with Vasopar 1Ml Inj.

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Liver

Caution

Limited information was available about using Vasopar 1Ml Inj in patients with liver disease. Inform your doctor before receiving the Vasopar 1Ml Inj if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Vasopar 1Ml Inj is contraindicated in patients with severe kidney impairment. Please let your doctor know if you have any history of kidney diseases before receiving Vasopar 1Ml Inj.

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Children

Unsafe

Vasopar 1Ml Inj is not recommended in children below 18 years.

FAQs

Vasopar 1Ml Inj is used to treat Low blood pressure (in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines), Diabetes insipidus and to Control bleeding from esophageal varices.
Vasopar 1Ml Inj contains Vasopressin, a human-made form of Vasopressin (antidiuretic hormone). When your body cannot produce enough Vasopressin, Vasopar 1Ml Inj is used to replace it. It helps treat diabetes insipidus. (a rare form of diabetes causing the production of large quantities of urine). Vasopressin increases the amount of water absorbed back into your kidneys. Thus, it helps treat diabetes insipidus.
Vasopar 1Ml Inj increases plasma levels of factor VIII activity in patients with bleeding disorders.
Vasopressin causes vasoconstriction by binding to V1 receptors on vascular smooth muscle. Thus, Vasopressin helps to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.
Optimal intake of fluids is recommended to prevent dehydration. However, avoid excess intake of water and other liquids like coffee, tea, cola, and energy drinks during the treatment. Excessive fluid intake while using Vasopar 1Ml Inj may lead to a build-up of water, which dilutes the salt in the body, leading to serious problems.
Generally, Vasopar 1Ml Inj is administered through intramuscular (IM), intravenous (IV), and subcutaneous routes. However, a healthcare professional will administer it; do not self-administer Vasopar 1Ml Inj.
Vasopar 1Ml Inj is safe when used only under the doctor’s supervision. However, it may cause side effects like nausea, vomiting, fatigue, fast or irregular heart rate, hyponatremia (low blood sodium levels), ischemia (restriction in blood supply), and redness/pain/swelling at the injection site.
Vasopar 1Ml Inj should not be taken by people who are allergic to any of its ingredients or have hypersensitivity to 8-L-arginine vasopressin or chlorobutanol.
Vasopar 1Ml Inj should be taken during pregnancy only if the doctor has prescribed it. The doctor will prescribe this medication only if the benefits outweigh the risks. Therefore, please consult your doctor before taking Vasopar 1Ml Inj if you are pregnant.
Vasopar 1Ml Inj is effective in the treatment of low blood pressure (in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines), diabetes insipidus, and to control bleeding from oesophageal varices. However, its effectiveness may vary from person to person.
The common side effects of Vasopar 1Ml Inj include nausea, vomiting, fatigue, fast or irregular heart rate, hyponatremia (low blood sodium levels), ischemia (restriction in blood supply), and redness/pain/swelling at the injection site. These side effects may not occur in everyone using this medication. However, if the side effects persist longer or worsen, please seek a doctor's advice.

Country of origin

INDIA

Manufacturer/Marketer address

E-11, MOTI NAGAR , NEW DELHI-110015
Other Info - VAS0101

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