Valcris-450 Tablet is used to treat cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. Also, Valcris-450 Tablet is used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV. Cytomegalovirus (CMV) retinitis is a viral infection of the retina (light-sensing cells) caused by cytomegalovirus.

Valcris-450 Tablet contains Valganciclovir which works by getting converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.  

Take Valcris-450 Tablet as prescribed by your doctor. You are advised to take Valcris-450 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhea, loss of appetite, cough, headache, stomach pain, nausea, fever, tiredness, or sinusitis (sinus infection). Most of these side effects of Valcris-450 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Valcris-450 Tablet or any other medicines, please tell your doctor. Avoid taking Valcris-450 Tablet if you are pregnant, as it may cause birth defects. If you are breastfeeding, do not take Valcris-450 Tablet as it may be excreted in human milk and cause adverse effects in the baby. Women are recommended to use effective contraceptive measures while taking Valcris-450 Tablet and for 30 days after treatment with Valcris-450 Tablet. Drive only if you are alert, as Valcris-450 Tablet may cause dizziness, tiredness, drowsiness, shakiness, or confusion.

Valcris-450 Tablet contains Valganciclovir, an antiviral drug used to treat cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. Valcris-450 Tablet gets converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.  Additionally, Valcris-450 Tablet is used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV.

• Diarrhoea

• Loss of appetite

• Cough

• Headache

• Stomach pain

• Nausea

• Fever

• Tiredness

• Sinusitis (sinus infection)

If you are allergic to Valcris-450 Tablet or any other medicines, please tell your doctor. If you have a low number of platelets, white blood cells or red blood cells and kidney problems, inform your doctor before taking Valcris-450 Tablet. Avoid taking Valcris-450 Tablet if you are pregnant as it may cause birth defects. If you are breastfeeding, do not take Valcris-450 Tablet as it may be excreted in human milk and cause adverse effects in the baby. Women are recommended to use effective contraceptive measures while taking Valcris-450 Tablet and 30 days after treatment with Valcris-450 Tablet. Men are advised to continue using contraceptive measures for 90 days after treatment with Valcris-450 Tablet. Drive only if you are alert as Valcris-450 Tablet may cause dizziness, tiredness, drowsiness, shakiness or confusion. If you are having blood dialysis or radiotherapy, please inform your doctor before taking Valcris-450 Tablet.

Drug-Drug Interaction: Valcris-450 Tablet may interact with antibiotics (imipenem + cilastatin, trimethoprim, dapsone), gout medicine (probenecid), antifungals (amphotericin B, flucytosine), antiprotozoals (pentamidine), anti-cancer (vinblastine, hydroxyurea, vincristine, doxorubicin), immunosuppressants (tacrolimus, mycophenolate mofetil, ciclosporin), HIV/AIDS medicines (tenofovir, zidovudine, stavudine, didanosine), medicines used to treat hepatitis B infection (adefovir).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have a low number of platelets, white blood cells or red blood cells and kidney problems, inform your doctor before taking Valcris-450 Tablet.

• TRIMETHOPRIM
• DAPSONE
• PROBENECID
• AMPHOTERICIN B
• IMIPENEM+CILASTATIN
• FLUCYTOSINE
• PENTAMIDINE
• VINBLASTINE
• HYDROXYUREA
• VINCRISTINE
• DOXORUBICIN
• TACROLIMUS
• MYCOPHENOLATE MOFETIL
• CICLOSPORIN
• TENOFOVIR DISOPROXIL
• ZIDOVUDINE
• STAVUDINE
• ADEFOVIR
• DIDANOSINE

• Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.

• Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.

• Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.

• Regular eye tests are recommended if you have a history of cytomegalovirus retinitis to identify issues related to eye health.

• If you touch damaged tablets accidentally, wash your hands with soap and water thoroughly. If any powder from tablets gets into your eyes, rinse with sterile or clean water.

Cytomegalovirus (CMV) retinitis: It is a viral infection of the retina (light-sensing cells) caused by cytomegalovirus. In serious cases, it may lead to blindness. CMV retinitis is more likely to affect people with a weakened immune system from HIV/AIDS. The symptoms include blurred vision, a blind spot in vision, floaters in the eye, loss of peripheral vision or flashes in the eye.