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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:47 PM IST
Twobrieye Ophthalmic Suspension 5 ml is used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It works by decreasing the production of aqueous humour; this helps lower the increased pressure in the eye. In some cases, this medicine may cause side effects such as blurred vision, eye redness, discomfort, drowsiness and bad taste in the mouth. Avoid touching the container's tip to the eye, eyelids, or surrounding areas as it may contaminate the product.
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Prescription drug

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Manufacturer/Marketer :

Eyekare

Consume Type :

OPHTHALMIC

Return Policy :

Not Returnable

About Twobrieye Ophthalmic Suspension 5 ml

Twobrieye Ophthalmic Suspension 5 ml is indicated for lowering high intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Glaucoma is an eye disease that causes damage to the optic nerve and results in reduced vision. Ocular hypertension is increased pressure in the eye due to poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow). 
 
Twobrieye Ophthalmic Suspension 5 ml is a combination of two drugs: Brinzolamide (carbonic anhydrase inhibitor) and Brimonidine (alpha-2 adrenergic receptor agonist). Twobrieye Ophthalmic Suspension 5 ml decreases the production of aqueous humour, thereby helping lower the increased pressure in the eye. 
 
In some cases, you may experience certain common side effects such as blurred vision, eye redness, discomfort, drowsiness and bad taste in the mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult a doctor if you are pregnant or breastfeeding. Twobrieye Ophthalmic Suspension 5 ml is not recommended for children below 18 years as the safety and effectiveness have not been established. Twobrieye Ophthalmic Suspension 5 ml might cause dizziness, drowsiness, and abnormal/blurred vision, so drive only if you have clear vision. Avoid touching the tip of the dropper as it may contaminate the contents.

Uses of Twobrieye Ophthalmic Suspension 5 ml

Treatment of Open-angle glaucoma or ocular hypertension.

Directions for Use

Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.

Medicinal Benefits

Twobrieye Ophthalmic Suspension 5 ml is a combination of two drugs: Brinzolamide (carbonic anhydrase inhibitors) and Brimonidine (alpha-2 adrenergic receptor agonists). Twobrieye Ophthalmic Suspension 5 ml is indicated for lowering high intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Twobrieye Ophthalmic Suspension 5 ml decreases the production of aqueous humour, thereby helping lower the increased pressure in the eye. 

How Twobrieye Ophthalmic Suspension 5 ml Works

Twobrieye Ophthalmic Suspension 5 ml is a combination of two drugs: Brinzolamide (carbonic anhydrase inhibitor) and Brimonidine (alpha-2 adrenergic receptor agonist). Twobrieye Ophthalmic Suspension 5 ml decreases the production of aqueous humour, thereby helping lower the increased pressure in the eye.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Twobrieye Ophthalmic Suspension 5 ml

  • Blurred/abnormal vision
  • Eye redness
  • Eye discomfort
  • Drowsiness
  • Bad taste in the mouth 
  • Dry mouth
  • Dizziness
  • Eye surface inflammation
  • Eye pain

What if I have taken an overdose of Twobrieye Ophthalmic Suspension 5 ml

Use Twobrieye Ophthalmic Suspension 5 ml only as prescribed by the physician. It is advised not to exceed the recommended dose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Twobrieye Ophthalmic Suspension 5 ml if you are allergic to any of its components, if you are taking monoamine oxidase inhibitors, antidepressants, if you have severe kidney problems or excess acidity in the blood. Inform your doctor if you have liver problems, narrow-angle glaucoma, dry eyes, cornea problems, coronary heart disease, depression, poor or disturbed blood circulation. Consult a doctor before using Twobrieye Ophthalmic Suspension 5 ml if you are pregnant or breastfeeding. Twobrieye Ophthalmic Suspension 5 ml is not recommended for children below 18 years as safety and effectiveness have not been established. Twobrieye Ophthalmic Suspension 5 ml might cause dizziness, drowsiness, abnormal/blurred vision; so, drive only if you are alert.

Diet & Lifestyle Advise

  • Include fresh fruits and vegetables in your diet.

  • Avoid smoking and alcohol consumption.

  • Avoid intake of baked foods such as cakes, cookies, doughnuts or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damage the optic nerve.

  • Cut down your coffee intake as it may increase pressure in the eye. Replace coffee with green tea.

  • Avoid exercises such as any position where the head is lower than the body, like an inverted yoga pose, as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.

Habit Forming

No

Therapeutic Class

ANTIGLAUCOMA AGENTS

Twobrieye Ophthalmic Suspension 5 ml Substitute

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Alcohol

Caution

Avoid consuming alcohol while using Twobrieye Ophthalmic Suspension 5 ml as it might cause increased dizziness and drowsiness. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Twobrieye Ophthalmic Suspension 5 ml belongs to pregnancy category C. Use effective contraception while using Twobrieye Ophthalmic Suspension 5 ml. Avoid using Twobrieye Ophthalmic Suspension 5 ml during pregnancy unless clearly indicated by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Twobrieye Ophthalmic Suspension 5 ml might pass into breastmilk. Avoid breastfeeding while using Twobrieye Ophthalmic Suspension 5 ml.

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Driving

Unsafe

Twobrieye Ophthalmic Suspension 5 ml might cause dizziness, drowsiness, and blurred/abnormal vision. So, avoid driving or operating machinery until your vision is clear.

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Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Twobrieye Ophthalmic Suspension 5 ml in patients with liver impairment.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Twobrieye Ophthalmic Suspension 5 ml in patients with kidney impairment. Twobrieye Ophthalmic Suspension 5 ml is not recommended for patients with severe kidney disease.

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Children

Unsafe

Twobrieye Ophthalmic Suspension 5 ml is not recommended for children below 18years as the safety and effectiveness have not been established.

FAQs

Twobrieye Ophthalmic Suspension 5 ml is used to lower high intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Twobrieye Ophthalmic Suspension 5 ml decreases the production of aqueous humour, thereby helps lower the increased pressure in the eye.
Continue using Twobrieye Ophthalmic Suspension 5 ml for as long as your doctor has prescribed it to you. Consult the doctor if irritation occurs or worsens.
Twobrieye Ophthalmic Suspension 5 ml might cause blurred or abnormal vision. So, avoid driving or operating machinery until your vision is clear to prevent any mishappening.
Do not wear contact lens while using Twobrieye Ophthalmic Suspension 5 ml. Remove contact lenses before using Twobrieye Ophthalmic Suspension 5 ml and put them back 15minutes after using Twobrieye Ophthalmic Suspension 5 ml.
Dry mouth could be a side-effect of Twobrieye Ophthalmic Suspension 5 ml. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol; drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Twobrieye Ophthalmic Suspension 5 ml can be used with other eye medications if prescribed by the doctor. However, maintain a gap of 5-10minutes between Twobrieye Ophthalmic Suspension 5 ml and other eye medications.

Country of origin

India

Manufacturer/Marketer address

902-B, Godrej Coliseum, Behind Everard Nagar,off.eatern express highway, Nr. Priyadarshini circle sion east mumbai - 400022 Phone: +91 22 61372223
Other Info - TWO0018

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