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Trombopag 25 Tablet 7's

Trombopag 25 Tablet 7's

Prescription drug
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Composition

ELTROMBOPAG-25MG

Manufacturer/Marketer

Natco Pharma Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Trombopag 25 Tablet

Trombopag 25 Tablet is used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. Trombopag 25 Tablet is also used to treat severe aplastic anaemia (SAA) in adults. Idiopathic thrombocytopenic purpura is an immune condition associated with low levels of platelets. Hepatitis C is an infection and inflammation of the liver caused by the hepatitis C virus. Severe aplastic anaemia is a condition in which the bone marrow doesn't make enough blood cells.

Trombopag 25 Tablet contains 'Eltrombopag', which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone that stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet production. Trombopag 25 Tablet works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Trombopag 25 Tablet helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.

Take Trombopag 25 Tablet as prescribed by your doctor. In some cases, Trombopag 25 Tablet can cause common side effects like nausea, diarrhoea, headache, muscle pain, tiredness, loss of appetite, fever, anaemia (lack of blood cells), cough and tingling numbness. These side effects are not familiar to everyone who takes Trombopag 25 Tablet and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you have any allergic reactions to Trombopag 25 Tablet or any other medicines before starting Trombopag 25 Tablet. It is essential to inform your doctor if you have any heart, kidney or liver problems, blood disorders, blood clotting problems and cataracts before starting Trombopag 25 Tablet. Consult the doctor if you are pregnant or planning to conceive. Trombopag 25 Tablet is not indicated for use in breastfeeding since it passes into the breast milk. Trombopag 25 Tablet may make you dizzy; hence, drive or operate machinery only when you are mentally alert. 

Uses of Trombopag 25 Tablet

Trombopag 25 Tablet is used to treat Low platelet count and Severe aplastic anaemia (SAA).

Medicinal Benefits

Trombopag 25 Tablet contains 'Eltrombopag,' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA) in adults. Trombopag 25 Tablet works by increasing megakaryocytes, the large bone marrow cells responsible for the production of platelets. The increase in these bone marrow cells stimulates the production of platelets. Thus Trombopag 25 Tablet prevents bleeding episodes by increasing the number of platelets in the blood.

Directions for Use

Tablet: Swallow it as a whole with a glass of water. Take it on an empty stomach as prescribed by the doctor. Do not crush, chew or break it. Powder for suspension: Mix the powder with the prescribed amount of water. Take it with or without food with an oral syringe in the dose and duration prescribed by the doctor.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trombopag 25 Tablet

  • Nausea
  • Diarrhoea
  • Headache
  • Muscle pain
  • Tiredness
  • Loss of appetite
  • Fever
  • Anaemia (lack of blood cells)
  • Cough
  • Tingling or numbness 

Drug Warnings

If you are known to be allergic to Trombopag 25 Tablet or other medicines, please inform your doctor in advance. Brief your medical history if you have blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases before starting Trombopag 25 Tablet. Take Trombopag 25 Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Trombopag 25 Tablet. Trombopag 25 Tablet is not recommended during pregnancy since it may have harmful effects on the foetus. Consult your doctor before using Trombopag 25 Tablet if you are a breastfeeding mother. Do not drive or operate machinery since Trombopag 25 Tablet may cause side effects like dizziness and tiredness, affecting your ability to concentrate and drive. Avoid or limit alcohol consumption with Trombopag 25 Tablet as it may affect the efficacy of Trombopag 25 Tablet. Trombopag 25 Tablet is not recommended for children less than one year of age in ITP and children less than two years of age in SAA. 

Drug Interactions

Drug-Drug Interactions: Trombopag 25 Tablet may interact with antacids, cholesterol-lowering drugs (statins), vitamin and mineral supplements (iron, calcium, magnesium, aluminium, selenium and zinc), anti-cancer drugs (methotrexate, topotecan), drugs for rheumatoid arthritis (ciclosporin, azathioprine), HIV/AIDS drugs (lopinavir, ritonavir), corticosteroids, and steroid hormones (danazol).

Drug-Food Interactions: Take Trombopag 25 Tablet at least two hours before or four hours after consuming dairy products, calcium-enriched foods, and fortified juices, as these interfere with the absorption of Trombopag 25 Tablet.

Drug-Disease Interactions: People with blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, and liver or kidney diseases should consult the doctor before taking Trombopag 25 Tablet.

Drug-Drug Interactions Checker List

  • METHOTREXATE
  • TOPOTECAN
  • CICLOSPORIN
  • AZATHIOPRINE
  • LOPINAVIR
  • RITONAVIR
  • DANAZOL
  • IRON
  • CALCIUM
  • ZINC

Habit Forming

No

Diet & Lifestyle Advise

  • Eat natural and healthy foods by cutting down on fatty and sodium-processed foods.
  • Exercise regularly to maintain good health.
  • Avoid smoking and alcohol intake.
  • Avoid activities like contact sports and use sharp objects like nail cutters and razors to decrease bleeding risk.
  • A high-protein diet, such as lean meat, chicken, crab, turkey, beef, and fish, can help increase platelet count.
  • EatingPapayaa is the best natural remedy to increase your platelet count, and you can also usePapayaa leave's mixture.
  • Include iron-rich foods like pomegranate, beetroot, green leafy vegetables, carrots, raisins, oranges, peanuts, kidney beans, and black-eyed peas in your diet.
  • Vitamin C sources like guava, black currant, red pepper, kiwi, green peppers, orange, strawberries, pineapple, peas, mango, grapefruit and broccoli can also boost your platelet count.

Special Advise

  • Please monitor your daily blood pressure and blood sugar levels, and if you notice any fluctuations, please consult a doctor.
  • Since Trombopag 25 Tablet affects liver enzymes, your doctor may suggest liver function tests to check your aspartate aminotransferase (AST), alanine aminotransferase (ALT) and bilirubin levels before starting treatment and every two weeks after the treatment with Trombopag 25 Tablet.
  • Trombopag 25 Tablet may also interfere with creatinine and bilirubin lab tests; hence, please inform your doctor and laboratory staff in advance.

Disease/Condition Glossary

Immune (idiopathic) thrombocytopenic purpura (ITP): It is an immune condition associated with low levels of platelets, and the blood doesn't clot normally. It occurs when the immune system mistakenly attacks its own platelets. ITP also occurs in children, followed by a viral infection. Symptoms of ITP may include easy bruising, bleeding from gums and nose, blood in urine and stools, heavy menstrual flow and pinpoint-sized reddish-purple spots on the lower legs.

Hepatitis C: It is an infection and inflammation of the liver caused by the hepatitis C virus. This virus can cause both acute and chronic hepatitis. Acute hepatitis C is a short-term illness that may last for six months. Chronic hepatitis C is a long-lasting disease that may lead to other severe liver cancer problems or cirrhosis (inflammation of the liver). Symptoms of hepatitis C include fatigue, nausea, loss of appetite and yellowing of the eyes and skin.

Severe aplastic anaemia (SAA): Aplastic anaemia is also called bone marrow aplasia. It is a condition in which the bone marrow doesn't make enough blood cells. SAA is commonly caused due to the damage of bone marrow. This damage can be a congenital disability or may occur because of radiation, chemotherapy, toxic chemicals, certain drugs and infections. Symptoms of SAA include fatigue, frequent infections, rapid heart rate and bleeding.

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Alcohol

Caution

Limit alcohol intake, along with Trombopag 25 Tablet, to attain the maximum efficacy of Trombopag 25 Tablet and rule out any possibility of worsening of side effects.

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Pregnancy

Unsafe

Trombopag 25 Tablet is not recommended in pregnancy. It may affect and harm the developing baby. Please consult your doctor if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Trombopag 25 Tablet is excreted into the breast milk. Please consult your doctor for more information before taking Trombopag 25 Tablet if you are a nursing mother.

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Driving

Caution

Trombopag 25 Tablet may cause dizziness and tiredness affecting your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Trombopag 25 Tablet. Trombopag 25 Tablet may cause an increase in liver enzymes. Your doctor may start the treatment with a lower dose of Trombopag 25 Tablet.

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Kidney

Caution

Trombopag 25 Tablet should be used with caution in cases of renal impairment. It is advised to seek doctor advice before starting Trombopag 25 Tablet if you have any kidney problems.

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Children

Caution

Trombopag 25 Tablet is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.

Country of origin

INDIA

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - TRO0369

Author Details

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FAQs

Trombopag 25 Tablet is used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. It is also used to treat severe aplastic anaemia (SAA) in adults.
Trombopag 25 Tablet contains Eltrombopag that stimulates platelet's production (helps in clotting) from megakaryocytes (bone marrow cells). Thus Trombopag 25 Tablet lowers the risk of bleeding episodes in diseases like immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA).
Do not stop using Trombopag 25 Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.
Trombopag 25 Tablet should be used with caution and only under doctor's supervision in cases of any allergic reactions, blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases.
Trombopag 25 Tablet decreases the risk of bleeding by increasing the platelet count in your body. However, you are advised to stay away from activities that may increase your risk of bleeding like contact sports and using sharp objects like razors and nail cutters.
It is advised to take Trombopag 25 Tablet on an empty stomach. Please take Trombopag 25 Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Trombopag 25 Tablet.
Trombopag 25 Tablet should be swallowed whole. Do not chew or crush the tablets.
It is usually taken once a day on an empty stomach, at least 1 hour before or 2 hours after eating. Take Trombopag 25 Tablet at around the same time every day.
It may take up to 2 weeks for patients to respond to Trombopag 25 Tablet.
Trombopag 25 Tablet should not be taken with foods, beverages, or other medicines that contain high concentrations of aluminium, calcium, iron, magnesium, selenium and zinc.
Trombopag 25 Tablet should be stored in a cool and dry place away from sunlight. Keep out of sight and reach of children.
Trombopag 25 Tablet can cause or increase the risk of severe liver issues. Check with your doctor straight away if you or your child experience nausea or vomiting, dark urine, light-coloured stools, right upper stomach pain, unusual exhaustion, or yellow eyes or skin while taking this medication.
Please take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

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