Trombonat 25 Tablet is used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. Trombonat 25 Tablet is also used to treat severe aplastic anaemia (SAA) in adults. Idiopathic thrombocytopenic purpura is an immune condition associated with low levels of platelets. Hepatitis C is an infection and inflammation of the liver caused by the hepatitis C virus. Severe aplastic anaemia is a condition in which the bone marrow doesn't make enough blood cells.

Trombonat 25 Tablet contains 'Eltrombopag', which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone that stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet production. Trombonat 25 Tablet works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Trombonat 25 Tablet helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.

Take Trombonat 25 Tablet as prescribed by your doctor. In some cases, Trombonat 25 Tablet can cause common side effects like nausea, diarrhoea, headache, muscle pain, tiredness, loss of appetite, fever, anaemia (lack of blood cells), cough and tingling numbness. These side effects are not familiar to everyone who takes Trombonat 25 Tablet and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you have any allergic reactions to Trombonat 25 Tablet or any other medicines before starting Trombonat 25 Tablet. It is essential to inform your doctor if you have any heart, kidney or liver problems, blood disorders, blood clotting problems and cataracts before starting Trombonat 25 Tablet. Consult the doctor if you are pregnant or planning to conceive. Trombonat 25 Tablet is not indicated for use in breastfeeding since it passes into the breast milk. Trombonat 25 Tablet may make you dizzy; hence, drive or operate machinery only when you are mentally alert. 

Trombonat 25 Tablet contains 'Eltrombopag,' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA) in adults. Trombonat 25 Tablet works by increasing megakaryocytes, the large bone marrow cells responsible for the production of platelets. The increase in these bone marrow cells stimulates the production of platelets. Thus Trombonat 25 Tablet prevents bleeding episodes by increasing the number of platelets in the blood.

• Nausea
• Diarrhoea
• Headache
• Muscle pain
• Tiredness
• Loss of appetite
• Fever
• Anaemia (lack of blood cells)
• Cough
• Tingling or numbness 

If you are known to be allergic to Trombonat 25 Tablet or other medicines, please inform your doctor in advance. Brief your medical history if you have blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases before starting Trombonat 25 Tablet. Take Trombonat 25 Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Trombonat 25 Tablet. Trombonat 25 Tablet is not recommended during pregnancy since it may have harmful effects on the foetus. Consult your doctor before using Trombonat 25 Tablet if you are a breastfeeding mother. Do not drive or operate machinery since Trombonat 25 Tablet may cause side effects like dizziness and tiredness, affecting your ability to concentrate and drive. Avoid or limit alcohol consumption with Trombonat 25 Tablet as it may affect the efficacy of Trombonat 25 Tablet. Trombonat 25 Tablet is not recommended for children less than one year of age in ITP and children less than two years of age in SAA. 

Drug-Drug Interactions: Trombonat 25 Tablet may interact with antacids, cholesterol-lowering drugs (statins), vitamin and mineral supplements (iron, calcium, magnesium, aluminium, selenium and zinc), anti-cancer drugs (methotrexate, topotecan), drugs for rheumatoid arthritis (ciclosporin, azathioprine), HIV/AIDS drugs (lopinavir, ritonavir), corticosteroids, and steroid hormones (danazol).

Drug-Food Interactions: Take Trombonat 25 Tablet at least two hours before or four hours after consuming dairy products, calcium-enriched foods, and fortified juices, as these interfere with the absorption of Trombonat 25 Tablet.

Drug-Disease Interactions: People with blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, and liver or kidney diseases should consult the doctor before taking Trombonat 25 Tablet.

• METHOTREXATE
• TOPOTECAN
• CICLOSPORIN
• AZATHIOPRINE
• LOPINAVIR
• RITONAVIR
• DANAZOL
• IRON
• CALCIUM
• ZINC

• Eat natural and healthy foods by cutting down on fatty and sodium-processed foods.
• Exercise regularly to maintain good health.
• Avoid smoking and alcohol intake.
• Avoid activities like contact sports and use sharp objects like nail cutters and razors to decrease bleeding risk.
• A high-protein diet, such as lean meat, chicken, crab, turkey, beef, and fish, can help increase platelet count.
• EatingPapayaa is the best natural remedy to increase your platelet count, and you can also usePapayaa leave's mixture.
• Include iron-rich foods like pomegranate, beetroot, green leafy vegetables, carrots, raisins, oranges, peanuts, kidney beans, and black-eyed peas in your diet.
• Vitamin C sources like guava, black currant, red pepper, kiwi, green peppers, orange, strawberries, pineapple, peas, mango, grapefruit and broccoli can also boost your platelet count.

• Please monitor your daily blood pressure and blood sugar levels, and if you notice any fluctuations, please consult a doctor.
• Since Trombonat 25 Tablet affects liver enzymes, your doctor may suggest liver function tests to check your aspartate aminotransferase (AST), alanine aminotransferase (ALT) and bilirubin levels before starting treatment and every two weeks after the treatment with Trombonat 25 Tablet.
• Trombonat 25 Tablet may also interfere with creatinine and bilirubin lab tests; hence, please inform your doctor and laboratory staff in advance.

Immune (idiopathic) thrombocytopenic purpura (ITP): It is an immune condition associated with low levels of platelets, and the blood doesn't clot normally. It occurs when the immune system mistakenly attacks its own platelets. ITP also occurs in children, followed by a viral infection. Symptoms of ITP may include easy bruising, bleeding from gums and nose, blood in urine and stools, heavy menstrual flow and pinpoint-sized reddish-purple spots on the lower legs.

Hepatitis C: It is an infection and inflammation of the liver caused by the hepatitis C virus. This virus can cause both acute and chronic hepatitis. Acute hepatitis C is a short-term illness that may last for six months. Chronic hepatitis C is a long-lasting disease that may lead to other severe liver cancer problems or cirrhosis (inflammation of the liver). Symptoms of hepatitis C include fatigue, nausea, loss of appetite and yellowing of the eyes and skin.

Severe aplastic anaemia (SAA): Aplastic anaemia is also called bone marrow aplasia. It is a condition in which the bone marrow doesn't make enough blood cells. SAA is commonly caused due to the damage of bone marrow. This damage can be a congenital disability or may occur because of radiation, chemotherapy, toxic chemicals, certain drugs and infections. Symptoms of SAA include fatigue, frequent infections, rapid heart rate and bleeding.