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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Trenaxa MF Tablet is used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, it is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. It contains two medicines, namely Tranexamic acid and Mefenamic acid. It may cause common side effects such as nausea, vomiting, diarrhoea, indigestion, heartburn, and headache.
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Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Trenaxa MF Tablet

Trenaxa MF Tablet is a combination medicine used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, Trenaxa MF Tablet is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Menstrual cramps, also known as dysmenorrhea, are characterized by cramps and pain during menstruation. Menorrhagia is a condition with abnormally heavy or prolonged bleeding during menstruation/periods.

Trenaxa MF Tablet is a combination of two drugs: Tranexamic acid (anti-fibrinolytic) and Mefenamic acid (NSAID). Tranexamic acid helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.

You are advised to take Trenaxa MF Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, indigestion, heartburn, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Trenaxa MF Tablet may cause dizziness, so drive with caution. Trenaxa MF Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Trenaxa MF Tablet as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Trenaxa MF Tablet

Treatment of Dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding).

Directions for Use

Take Trenaxa MF Tablet with food to prevent stomach upset. Swallow it as a whole with a glass of water, do not chew or break it.

Medicinal Benefits

Trenaxa MF Tablet is a combination of two drugs, namely: Tranexamic acid and Mefenamic acid. Trenaxa MF Tablet is used to treat abdominal pain, dysmenorrhea (period pain), and menorrhagia (heavy menstrual bleeding). Additionally, Trenaxa MF Tablet is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Tranexamic acid is an anti-fibrinolytic agent that helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid is an NSAID that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. By blocking the COX enzyme's effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Trenaxa MF Tablet helps treat heavy bleeding and pains/cramps during periods.

How Trenaxa MF Tablet Works

Trenaxa MF Tablet is a combination of two drugs: Tranexamic acid (anti-fibrinolytic) and Mefenamic acid (NSAID). Tranexamic acid helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trenaxa MF Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Indigestion
  • Heartburn
  • Headache
  • Musculoskeletal pain
  • Stomach pain

What if I have taken an overdose of Trenaxa MF Tablet

Do not take more than the prescribed dose of Trenaxa MF Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Trenaxa MF Tablet if you are allergic to any of its contents or if you have severe heart failure. Inform your doctor if you have/had deep vein thrombosis, pulmonary embolism (block a blood vessel in the lungs), coagulopathy (formation of blood clots), epilepsy, irregular periods, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Trenaxa MF Tablet may cause dizziness and drowsiness, so drive only if you are alert. Trenaxa MF Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Trenaxa MF Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Do not take any other NSAIDs for pain relief along with Trenaxa MF Tablet unless prescribed.

Drug-Drug Interactions

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Tranexamic acidDrospirenone
Critical
Tranexamic acidEthinylestradiol
Critical

Drug-Drug Interactions

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Tranexamic acidDrospirenone
Critical
How does the drug interact with Trenaxa MF Tablet 6's:
Taking drospirenone with Trenaxa MF Tablet 6's may increase the risk of blood clot formation.

How to manage the interaction:
Taking Trenaxa MF Tablet 6's with Drospirenone is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
Tranexamic acidEthinylestradiol
Critical
How does the drug interact with Trenaxa MF Tablet 6's:
Taking Ethinylestradiol with Trenaxa MF Tablet 6's may increase the risk of blood clot formation.

How to manage the interaction:
Taking Ethinylestradiol with Trenaxa MF Tablet 6's is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
Tranexamic acidLevonorgestrel
Critical
How does the drug interact with Trenaxa MF Tablet 6's:
Taking Levonorgestrel with Trenaxa MF Tablet 6's may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.

How to manage the interaction:
Taking Trenaxa MF Tablet 6's with Levonorgestrel may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Tranexamic acidEtonogestrel
Critical
How does the drug interact with Trenaxa MF Tablet 6's:
Co-administration of Trenaxa MF Tablet 6's may cause blood clotting when taken with Etonogestrel.

How to manage the interaction:
Taking Trenaxa MF Tablet 6's with Etonogestrel is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
Tranexamic acidMedroxyprogesterone
Critical
How does the drug interact with Trenaxa MF Tablet 6's:
Taking Medroxyprogesterone acetate with Trenaxa MF Tablet 6's may increase the risk of blood clots.

How to manage the interaction:
Taking Medroxyprogesterone with Trenaxa MF Tablet 6's is not recommended but can be taken if prescribed by a doctor. Consult your doctor immediately if you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg. Do not stop using any medications without talking to your doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Trenaxa MF Tablet 6's:
Coadministration of Trenaxa MF Tablet 6's with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Trenaxa MF Tablet 6's with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidMeloxicam
Critical
How does the drug interact with Trenaxa MF Tablet 6's:
Co-administration of Trenaxa MF Tablet 6's with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Trenaxa MF Tablet 6's with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Tranexamic acidConjugated Estrogens
Severe
How does the drug interact with Trenaxa MF Tablet 6's:
Co-administration of Conjugated estrogen with Trenaxa MF Tablet 6's can increase the risk of blood clots.

How to manage the interaction:
Taking Conjugated estrogen with Trenaxa MF Tablet 6's may result in interaction, it can be taken only if your doctor has advised it. However, if you experience chest pain, shortness of breath, coughing up blood, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidCarfilzomib
Severe
How does the drug interact with Trenaxa MF Tablet 6's:
Co-administration of Carfilzomib with Trenaxa MF Tablet 6's can increase the risk of blood clots.

How to manage the interaction:
Taking carfilzomib with Trenaxa MF Tablet 6's is not recommended due to its increased effects, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidEstrone
Severe
How does the drug interact with Trenaxa MF Tablet 6's:
Co-administration of Estrone with Trenaxa MF Tablet 6's can increase the risk of blood clots.

How to manage the interaction:
Taking Estrone with Trenaxa MF Tablet 6's can possibly lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a healthy diet. Include vegetables, fruits, and whole grains in your meals.

  • Stay hydrated; drink plenty of water.

  • Cut down on sugars, salts, spicy food, coffee, and alcohol.

  • A heating pad can help ease the pain by placing it on the belly or lower back.

  • Exercise can help ease the pain of menstrual cramps.

  • Avoid stress by performing meditation or yoga.

  • Massage your lower back or abdomen to relieve the pain.

  • Take proper rest.

Habit Forming

No

Therapeutic Class

ANTIFIBRINOLYTIC AGENTS

Trenaxa MF Tablet Substitute

Substitutes safety advice
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  • Texakind-MF Tablet 10's

    28.71per tablet
  • Trenaxa MF Tablet 10's

    47.88per tablet
  • Tenacid-MF Tablet 10's

    18.00per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Trenaxa MF Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Trenaxa MF Tablet if you are breastfeeding, your doctor will decide if Trenaxa MF Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Trenaxa MF Tablet may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with renal disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Trenaxa MF Tablet should not be given to children as the safety and effectiveness were not established.

FAQs

Trenaxa MF Tablet is used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, it is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache.
Trenaxa MF Tablet contains Tranexamic acid and Mefenamic acid. Tranexamic acid helps the body's natural blood clot process by preventing the breakdown of fibrin, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.
Diarrhoea might be a side-effect of Trenaxa MF Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.
Trenaxa MF Tablet should not be taken for longer durations unless prescribed by the doctor. Trenaxa MF Tablet is usually prescribed for a few days at the time of heavy bleeding and cramps.
Trenaxa MF Tablet is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Trenaxa MF Tablet only as prescribed and do not overdose.
Consult your doctor before taking contraceptive pills along with Trenaxa MF Tablet. When taken together, there is an increased risk of deep vein thrombosis (blood clot in the deep vein, usually legs).
Trenaxa MF Tablet contains mefenamic acid, an NSAID which might increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke. Therefore, avoid taking Trenaxa MF Tablet if you have heart-related problems unless prescribed by the doctor.
Trenaxa MF Tablet typically starts to show its effects within 1-2 hours of taking it, and it helps to reduce heavy menstrual bleeding by improving blood clotting but does not stop bleeding. However, the exact duration for bleeding to stop can vary from one person to other.
Yes, Trenaxa MF Tablet can cause acidity. If you experience heartburn and indigestion, it's advisable to take Trenaxa MF Tablet with food to minimize discomfort. If the symptoms persist, please consult your doctor.
Yes, Trenaxa MF Tablet is safe if you take as per the dose and duration prescribed by your doctor. However, it's important to be aware of potential side effects and contraindications. Always consult your doctor before starting any new medication to ensure it is safe for you, especially if you have pre-existing conditions or are taking other medications.
Always follow your doctor's instructions regarding dosage and duration. Usually it is prescribed for a short duration. Do not exceed the prescribed duration. As overuse can lead to side effects and other health issues.
Trenaxa MF Tablet is a combination of two drugs, tranexamic acid (anti-fibrinolytic) and mefenamic acid (NSAID).
Yes, do not take Trenaxa MF Tablet if you are allergic to any of its contents or if you have severe heart failure. Inform your doctor if you have/had deep vein thrombosis, pulmonary embolism (block a blood vessel in the lungs), coagulopathy (formation of blood clots), epilepsy, irregular periods, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Do not take any other NSAIDs for pain relief along with Trenaxa MF Tablet unless prescribed.
Store Trenaxa MF Tablet at a temperature not exceeding 25°C. Protect it from light and moisture. Keep out of reach of children.
Yes, you can take Trenaxa MF Tablet with food. It is often recommended to take it after a meal to avoid stomach upset or other gastrointestinal side effects.
Please consult your doctor if you are pregnant. Your doctor will prescribes Trenaxa MF Tablet only if the benefits outweigh the risks.
The common side effects of Trenaxa MF Tablet are nausea, vomiting, diarrhoea, indigestion, heartburn, and headache. If any of these side effects persist or worsen, please consult your doctor.
You are recommended to consult your doctor before taking other medicines with Trenaxa MF Tablet to avoid possible interactions.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - TRE0009

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