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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 30, 2024 | 3:22 PM IST
Trenaxa MF Tablet is used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, it is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. It contains two medicines, namely Tranexamic acid and Mefenamic acid. It may cause common side effects such as nausea, vomiting, diarrhoea, indigestion, heartburn, and headache.
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Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-26

for this medicine

About Trenaxa MF Tablet

Trenaxa MF Tablet is a combination medicine used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, Trenaxa MF Tablet is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Menstrual cramps, also known as dysmenorrhea, are characterized by cramps and pain during menstruation. Menorrhagia is a condition with abnormally heavy or prolonged bleeding during menstruation/periods.

Trenaxa MF Tablet is a combination of two drugs: Tranexamic acid (anti-fibrinolytic) and Mefenamic acid (NSAID). Tranexamic acid helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.

You are advised to take Trenaxa MF Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, indigestion, heartburn, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Trenaxa MF Tablet may cause dizziness, so drive with caution. Trenaxa MF Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Trenaxa MF Tablet as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Trenaxa MF Tablet

Treatment of Dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding).

Medicinal Benefits

Trenaxa MF Tablet is a combination of two drugs, namely: Tranexamic acid and Mefenamic acid. Trenaxa MF Tablet is used to treat abdominal pain, dysmenorrhea (period pain), and menorrhagia (heavy menstrual bleeding). Additionally, Trenaxa MF Tablet is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Tranexamic acid is an anti-fibrinolytic agent that helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid is an NSAID that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. By blocking the COX enzyme's effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Trenaxa MF Tablet helps treat heavy bleeding and pains/cramps during periods.

Directions for Use

Take Trenaxa MF Tablet with food to prevent stomach upset. Swallow it as a whole with a glass of water, do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trenaxa MF Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Indigestion
  • Heartburn
  • Headache
  • Musculoskeletal pain
  • Stomach pain

Drug Warnings

Do not take Trenaxa MF Tablet if you are allergic to any of its contents or if you have severe heart failure. Inform your doctor if you have/had deep vein thrombosis, pulmonary embolism (block a blood vessel in the lungs), coagulopathy (formation of blood clots), epilepsy, irregular periods, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Trenaxa MF Tablet may cause dizziness and drowsiness, so drive only if you are alert. Trenaxa MF Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Trenaxa MF Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Do not take any other NSAIDs for pain relief along with Trenaxa MF Tablet unless prescribed.

Drug Interactions

Drug-Drug Interactions: Trenaxa MF Tablet may interact with pain killers (ibuprofen, celecoxib), anti-depressant (duloxetine, fluoxetine, sertraline), fibrinolytic medicine, birth control pills, drugs that prevent bleeding (factor IX complex, anti-inhibitor coagulant concentrates), blood thinners (anticoagulants such as warfarin, heparin)

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have deep vein thrombosis, pulmonary embolism (blockage of blood vessels in the lungs), coagulopathy (formation of blood clots), epilepsy, peptic ulcers, asthma, glaucoma, gastrointestinal toxicity, high blood pressure, or heart problems.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • CELECOXIB
  • DULOXETINE
  • FLUOXETINE
  • SERTRALINE

Habit Forming

No

Diet & Lifestyle Advise

  • Follow a healthy diet. Include vegetables, fruits, and whole grains in your meals.

  • Stay hydrated; drink plenty of water.

  • Cut down on sugars, salts, spicy food, coffee, and alcohol.

  • A heating pad can help ease the pain by placing it on the belly or lower back.

  • Exercise can help ease the pain of menstrual cramps.

  • Avoid stress by performing meditation or yoga.

  • Massage your lower back or abdomen to relieve the pain.

  • Take proper rest.

Disease/Condition Glossary

Menorrhagia: Menorrhagia is a condition with abnormally heavy or prolonged bleeding during menstruation/periods. The exact cause of menorrhagia is unknown, but it could be due to hormonal imbalance, dysfunction of the ovaries, uterine fibroids, polyps, inherited bleeding disorders, intrauterine devices, or medications. Symptoms include socking through one/more sanitary pads/tampons for every hour, needing to use double sanitary protection to control the flow, needing to wake up during the night to change the pad, bleeding for more than a week, passing blood clots, unable to do daily activities due to heavy flow, tiredness, and fatigue.

Dysmenorrhea: Menstrual cramps, also known as dysmenorrhea, is characterised by cramps and pain during menstruation due to heavy flow. Pain, cramps, and discomfort during periods are normal. However, excessive pain during periods is not normal and requires medication. Symptoms of dysmenorrhea include intense throbbing pain in the lower abdomen, dull, continuous aches, pain in the lower back and thighs, nausea, headache, and dizziness. The pain usually starts 1-3 days prior to the period, peaks one day before the period starts, and subsides 2-3days after the onset of the period.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Trenaxa MF Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Trenaxa MF Tablet if you are breastfeeding, your doctor will decide if Trenaxa MF Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Trenaxa MF Tablet may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with renal disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Trenaxa MF Tablet should not be given to children as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, India.
Other Info - TRE0393

Author Details

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FAQs

Trenaxa MF Tablet is used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, it is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache.
Trenaxa MF Tablet contains Tranexamic acid and Mefenamic acid. Tranexamic acid helps the body's natural blood clot process by preventing the breakdown of fibrin, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.
Diarrhoea might be a side-effect of Trenaxa MF Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.
Trenaxa MF Tablet should not be taken for longer durations unless prescribed by the doctor. Trenaxa MF Tablet is usually prescribed for a few days at the time of heavy bleeding and cramps.
Trenaxa MF Tablet is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Trenaxa MF Tablet only as prescribed and do not overdose.
Consult your doctor before taking contraceptive pills along with Trenaxa MF Tablet . When taken together, there is an increased risk of deep vein thrombosis (blood clot in the deep vein, usually legs).
Trenaxa MF Tablet contains mefenamic acid, an NSAID which might increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke. Therefore, avoid taking Trenaxa MF Tablet if you have heart-related problems unless prescribed by the doctor.
Trenaxa MF Tablet typically starts to show its effects within 1-2 hours of taking it, and it helps to reduce heavy menstrual bleeding by improving blood clotting but does not stop bleeding. However, the exact duration for bleeding to stop can vary from one person to other.
Yes, Trenaxa MF Tablet can cause acidity. If you experience heartburn and indigestion, it's advisable to take Trenaxa MF Tablet with food to minimize discomfort. If the symptoms persist, please consult your doctor.
Yes, Trenaxa MF Tablet is safe if you take as per the dose and duration prescribed by your doctor. However, it's important to be aware of potential side effects and contraindications. Always consult your doctor before starting any new medication to ensure it is safe for you, especially if you have pre-existing conditions or are taking other medications.
Always follow your doctor's instructions regarding dosage and duration. Usually it is prescribed for a short duration. Do not exceed the prescribed duration. As overuse can lead to side effects and other health issues.
Trenaxa MF Tablet is a combination of two drugs, tranexamic acid (anti-fibrinolytic) and mefenamic acid (NSAID).
Yes, do not take Trenaxa MF Tablet if you are allergic to any of its contents or if you have severe heart failure. Inform your doctor if you have/had deep vein thrombosis, pulmonary embolism (block a blood vessel in the lungs), coagulopathy (formation of blood clots), epilepsy, irregular periods, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Do not take any other NSAIDs for pain relief along with Trenaxa MF Tablet unless prescribed.
Store Trenaxa MF Tablet at a temperature not exceeding 25°C. Protect it from light and moisture. Keep out of reach of children.
Yes, you can take Trenaxa MF Tablet with food. It is often recommended to take it after a meal to avoid stomach upset or other gastrointestinal side effects.
Please consult your doctor if you are pregnant. Your doctor will prescribes Trenaxa MF Tablet only if the benefits outweigh the risks.
The common side effects of Trenaxa MF Tablet are nausea, vomiting, diarrhoea, indigestion, heartburn, and headache. If any of these side effects persist or worsen, please consult your doctor.
You are recommended to consult your doctor before taking other medicines with Trenaxa MF Tablet to avoid possible interactions.

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