TRAMAFLAM TABLET is used to prevent and treat moderate to severe pain. Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body).

TRAMAFLAM TABLET contains Tramadol, which works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to the brain. Also, TRAMAFLAM TABLET improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain.

Take TRAMAFLAM TABLET as prescribed. Your doctor will advise you how often you take TRAMAFLAM TABLET based on your medical condition. In some cases, you may experience nausea, dizziness, headache, vomiting, dry mouth, drowsiness, constipation, sweating or tiredness. Most of these side effects of TRAMAFLAM TABLET do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are known to be allergic to TRAMAFLAM TABLET or any other medicines, please tell your doctor. TRAMAFLAM TABLET is not recommended for children below 12 years of age. If you are pregnant or breastfeeding or have a history of fits, please inform your doctor before taking TRAMAFLAM TABLET. Do not consume alcohol with TRAMAFLAM TABLET as it may increase the risk of side effects. Avoid frequent or high doses as it may lead to addiction.

TRAMAFLAM TABLET is a pain killer that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain, thereby, inhibiting the transmission of pain signals from nerves to the brain. Thus, TRAMAFLAM TABLET improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. TRAMAFLAM TABLET is used to relieve pain after surgery, pain caused by an injury or illness.

• Nausea
• Dizziness
• Headache
• Vomiting
• Dry mouth
• Drowsiness
• Constipation
• Sweating
• Tiredness

Do not stop taking TRAMAFLAM TABLET suddenly as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to TRAMAFLAM TABLET or any other medicines, please tell your doctor. TRAMAFLAM TABLET is not recommended for children below 12 years of age and for children suffering from breathing problems as it may worsen the symptoms of TRAMAFLAM TABLET toxicity. If you are pregnant or breastfeeding or have a history of epilepsy (fits), please inform your doctor before taking TRAMAFLAM TABLET. Do not consume alcohol with TRAMAFLAM TABLET as it may increase the risk of side effects. TRAMAFLAM TABLET should be taken with caution by the patients taking sleeping pills, tranquillizers, hypnotics or other opiate containing pain killers.

Drug-Drug Interaction: TRAMAFLAM TABLET may have interaction with pain killers (pentazocine, buprenorphine, nalbuphine), blood thinners (warfarin), anti-anxiety drugs (alprazolam), fits related medicines (carbamazepine), medicines used to prevent nausea (ondansetron), antifungal drugs (ketoconazole), antibiotic (ciprofloxacin, erythromycin), anticancer drugs (ceritinib, lapatinib), immunosuppressants (fingolimod), antidepressants (fluoxetine, doxepin), antipsychotics (droperidol), and HIV/AIDS drugs (saquinavir).

Drug- Food Interaction: TRAMAFLAM TABLET may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with TRAMAFLAM TABLET as it may increase TRAMAFLAM TABLET levels in the body. Also, avoid alcohol consumption while taking TRAMAFLAM TABLET as it may increase the risk of adverse effects such as drowsiness, dizziness and difficulty in concentrating.

Drug-Disease Interaction: People with severe kidney or liver problems, fits and breathing problems should consult a doctor before taking TRAMAFLAM TABLET.

• BUPRENORPHINE
• WARFARIN
• ALPRAZOLAM
• CARBAMAZEPINE
• ONDANSETRON
• KETOCONAZOLE
• CIPROFLOXACIN
• ERYTHROMYCIN
• FLUOXETINE
• DOXEPIN
• SAQUINAVIR

• Do regular exercise such as swimming or walking.

• Drink plenty of water while taking TRAMAFLAM TABLET to avoid dry mouth.
• Maintain a fibre rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while taking TRAMAFLAM TABLET.
• Avoid consumption of alcohol and quit smoking.

• Patients with severe liver or kidney insufficiency should avoid taking TRAMAFLAM TABLET.

• If your children have any breathing problem, please inform your doctor as it may worsen the toxicity symptoms.

• Do not give TRAMAFLAM TABLET to others. Use TRAMAFLAM TABLET only when prescribed by a doctor and avoid frequent or doses as it may cause addiction.

• TRAMAFLAM TABLET may impair mental or physical abilities required for the performance of hazardous activities like driving a motor vehicle or operating heavy machinery.

Pain: It is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body). Pain is highly subjective as some people have a high tolerance for pain while others have a low tolerance. Although pain is inconvenient and unpleasant, it hints about causes when something is wrong in the body. Pain may be caused due to cramps, headache, bone fractures, stomach pain, arthritis (swelling of one or more joints), muscle strain or overuse, cuts, flu, irritable bowel syndrome (an intestinal disorder causing stomach pain, diarrhoea or constipation) and fibromyalgia (muscle pain with stiffness and tenderness).