DOMADOL TABLET is used to prevent and treat moderate to severe pain. Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body).

DOMADOL TABLET contains Tramadol, which works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to the brain. Also, DOMADOL TABLET improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain.

Take DOMADOL TABLET as prescribed. Your doctor will advise you how often you take DOMADOL TABLET based on your medical condition. In some cases, you may experience nausea, dizziness, headache, vomiting, dry mouth, drowsiness, constipation, sweating or tiredness. Most of these side effects of DOMADOL TABLET do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are known to be allergic to DOMADOL TABLET or any other medicines, please tell your doctor. DOMADOL TABLET is not recommended for children below 12 years of age. If you are pregnant or breastfeeding or have a history of fits, please inform your doctor before taking DOMADOL TABLET. Do not consume alcohol with DOMADOL TABLET as it may increase the risk of side effects. Avoid frequent or high doses as it may lead to addiction.

DOMADOL TABLET is a pain killer that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain, thereby, inhibiting the transmission of pain signals from nerves to the brain. Thus, DOMADOL TABLET improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. DOMADOL TABLET is used to relieve pain after surgery, pain caused by an injury or illness.

• Nausea
• Dizziness
• Headache
• Vomiting
• Dry mouth
• Drowsiness
• Constipation
• Sweating
• Tiredness

Do not stop taking DOMADOL TABLET suddenly as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to DOMADOL TABLET or any other medicines, please tell your doctor. DOMADOL TABLET is not recommended for children below 12 years of age and for children suffering from breathing problems as it may worsen the symptoms of DOMADOL TABLET toxicity. If you are pregnant or breastfeeding or have a history of epilepsy (fits), please inform your doctor before taking DOMADOL TABLET. Do not consume alcohol with DOMADOL TABLET as it may increase the risk of side effects. DOMADOL TABLET should be taken with caution by the patients taking sleeping pills, tranquillizers, hypnotics or other opiate containing pain killers.

Drug-Drug Interaction: DOMADOL TABLET may have interaction with pain killers (pentazocine, buprenorphine, nalbuphine), blood thinners (warfarin), anti-anxiety drugs (alprazolam), fits related medicines (carbamazepine), medicines used to prevent nausea (ondansetron), antifungal drugs (ketoconazole), antibiotic (ciprofloxacin, erythromycin), anticancer drugs (ceritinib, lapatinib), immunosuppressants (fingolimod), antidepressants (fluoxetine, doxepin), antipsychotics (droperidol), and HIV/AIDS drugs (saquinavir).

Drug- Food Interaction: DOMADOL TABLET may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with DOMADOL TABLET as it may increase DOMADOL TABLET levels in the body. Also, avoid alcohol consumption while taking DOMADOL TABLET as it may increase the risk of adverse effects such as drowsiness, dizziness and difficulty in concentrating.

Drug-Disease Interaction: People with severe kidney or liver problems, fits and breathing problems should consult a doctor before taking DOMADOL TABLET.

• BUPRENORPHINE
• WARFARIN
• ALPRAZOLAM
• CARBAMAZEPINE
• ONDANSETRON
• KETOCONAZOLE
• CIPROFLOXACIN
• ERYTHROMYCIN
• FLUOXETINE
• DOXEPIN
• SAQUINAVIR

• Do regular exercise such as swimming or walking.

• Drink plenty of water while taking DOMADOL TABLET to avoid dry mouth.
• Maintain a fibre rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while taking DOMADOL TABLET.
• Avoid consumption of alcohol and quit smoking.

• Patients with severe liver or kidney insufficiency should avoid taking DOMADOL TABLET.

• If your children have any breathing problem, please inform your doctor as it may worsen the toxicity symptoms.

• Do not give DOMADOL TABLET to others. Use DOMADOL TABLET only when prescribed by a doctor and avoid frequent or doses as it may cause addiction.

• DOMADOL TABLET may impair mental or physical abilities required for the performance of hazardous activities like driving a motor vehicle or operating heavy machinery.

Pain: It is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body). Pain is highly subjective as some people have a high tolerance for pain while others have a low tolerance. Although pain is inconvenient and unpleasant, it hints about causes when something is wrong in the body. Pain may be caused due to cramps, headache, bone fractures, stomach pain, arthritis (swelling of one or more joints), muscle strain or overuse, cuts, flu, irritable bowel syndrome (an intestinal disorder causing stomach pain, diarrhoea or constipation) and fibromyalgia (muscle pain with stiffness and tenderness).