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About Tolvanix 15 mg Tablet
Tolvanix 15 mg Tablet is used to treat hyponatremia (low levels of sodium) in patients with heart failure, liver disease and hormonal imbalances such as Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Additionally, Tolvanix 15 mg Tablet is also used to treat autosomal dominant polycystic kidney disease (ADPKD).
Tolvanix 15 mg Tablet contains ‘tolvaptan’ that works by blocking the effect of vasopressin, resulting in decreased water reabsorption, a net increase in free water excretion (aquaresis) and an increase in serum sodium concentrations. This decrease in free water is not associated with an increased excretion of sodium or potassium ions; the increase in serum sodium concentration is solely a result of increased urine production.
You are advised to take Tolvanix 15 mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as dizziness, headache, dry mouth, fatigue, diarrhoea, thirst and increased urge to urinate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not take Tolvanix 15 mg Tablet if you are pregnant as it may cause foetal harm. Consult your doctor before taking Tolvanix 15 mg Tablet if you are breastfeeding. Tolvanix 15 mg Tablet is not recommended for children below 18 years as the efficacy and safety have not been established. Tolvanix 15 mg Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects.
Uses of Tolvanix 15 mg Tablet
Directions for Use
Medicinal Benefits
Tolvanix 15 mg Tablet belongs to a group of medicines called vasopressin V2 receptor antagonist. Tolvanix 15 mg Tablet is used to treat hyponatremia (low levels of sodium) in patients with heart failure, liver disease and hormonal imbalances such as Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Besides this, Tolvanix 15 mg Tablet is also used to treat autosomal dominant polycystic kidney disease (ADPKD). Tolvanix 15 mg Tablet works by blocking the effect of vasopressin, a hormone which is involved in the formation of cysts in ADPKD patients. By blocking the effect of vasopressin, Tolvanix 15 mg Tablet slows down the development of cysts in kidneys and reduces the symptoms of the disease. Tolvanix 15 mg Tablet antagonises the effect of vasopressin; this results in an increase in free water clearance and decreases urine osmolality due to increased urinary excretion, thereby increasing serum sodium concentrations.
How Tolvanix 15 mg Tablet Works
Storage
Side Effects of Tolvanix 15 mg Tablet
What if I have taken an overdose of Tolvanix 15 mg Tablet
Drug Warnings
Do not take Tolvanix 15 mg Tablet if you are allergic to any of its contents, if you have raised liver enzymes in the blood, very low blood volume, if there is no urine production, if you cannot tell that you are thirsty. Inform your doctor if you have liver disease, difficulty in urination, diabetes, high levels of uric acid, advanced kidney disease or if you have to restrict fluid intake due to certain medical conditions. Do not take Tolvanix 15 mg Tablet if you are pregnant as it may cause foetal harm. Consult your doctor before taking Tolvanix 15 mg Tablet if you are breastfeeding. Tolvanix 15 mg Tablet is not recommended for children below 18 years as efficacy and safety have not been established. Tolvanix 15 mg Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness.
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Alcohol
Unsafe
Avoid consuming alcohol while taking Tolvanix 15 mg Tablet as it may cause increased dizziness.
Pregnancy
Unsafe
Tolvanix 15 mg Tablet belongs to pregnancy category C. Tolvanix 15 mg Tablet is not recommended for use in pregnant women as it may cause foetal harm. Women of childbearing age must use effective contraception while taking Tolvanix 15 mg Tablet.
Breast Feeding
Unsafe
Tolvanix 15 mg Tablet is not recommended for use in breastfeeding women. Consult your doctor if you are breastfeeding; your doctor will decide whether Tolvanix 15 mg Tablet can be taken by breastfeeding mothers or not.
Driving
Caution
Tolvanix 15 mg Tablet may cause dizziness, weakness and tiredness. Do not drive or operate heavy machinery if you feel dizzy.
Liver
Caution
Dose adjustment may be needed. Tolvanix 15 mg Tablet should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have liver problems or any concerns regarding this.
Kidney
Caution
Tolvanix 15 mg Tablet should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney problems or any concerns regarding this.
Children
Unsafe
Tolvanix 15 mg Tablet is not recommended for children below 18 years as efficacy and safety have not been established.
Tolvanix 15 mg Tablet is used to treat hyponatremia (low levels of sodium) in patients with heart failure, liver disease and hormonal imbalances such as Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Additionally, Tolvanix 15 mg Tablet is also used to treat autosomal dominant polycystic kidney disease (ADPKD).
Tolvanix 15 mg Tablet works by blocking the effect of vasopressin, a hormone which is involved in the formation of cysts in ADPKD patients. By blocking the effect of vasopressin, Tolvanix 15 mg Tablet slows down the development of cysts in the kidneys, reduces the symptoms of the disease, and increases urine production. Thereby increases serum sodium concentrations.
Dry mouth could be a side-effect of Tolvanix 15 mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Diarrhoea could be a side-effect of Tolvanix 15 mg Tablet. Drink plenty of fluid to prevent dehydration if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or if you find blood in stools.
Tolvanix 15 mg Tablet may cause the liver to not work properly. Consult your doctor immediately if you experience nausea, vomiting, fever, loss of appetite, abdominal pain, tiredness, dark urine, jaundice, itching and flu-like symptoms.
Tolvanix 15 mg Tablet may cause water loss due to increased urine production. This might result in side-effects such as thirst, dry mouth and kidney problems. To prevent this, drink plenty of water regularly. Drink 1-2 glasses of water before going to bed even though you are not thirsty. Special care must be taken in patients with diseases that might reduce fluid intake.
Consult your doctor before taking Tolvanix 15 mg Tablet if you are diabetic as Tolvanix 15 mg Tablet might increase the blood sugar levels. Regular monitoring of blood glucose levels while taking Tolvanix 15 mg Tablet is advised.
You are advised to take Tolvanix 15 mg Tablet for the duration prescribed by the doctor. Tolvanix 15 mg Tablet should not be taken for more than 30 days.
Tolvanix 15 mg Tablet might increase the blood sugar levels. Consult the doctor if you are diabetic.
Do not take Tolvanix 15 mg Tablet if you are allergic to any of its components, if you have raised liver enzymes in the blood, very low blood volume, if there is no urine production, or if you cannot tell that you are thirsty.
Avoid consuming grapefruit or its juice while taking Tolvanix 15 mg Tablet as it might increase the effects of the medicine in the body.
Do not exceed the prescribed dose as it might cause an overdose. Taking an excess of Tolvanix 15 mg Tablet may cause excessive thirst, dizziness, excessive urination, or fainting. Consult the doctor if you experience these symptoms.
Tolvanix 15 mg Tablet is not recommended for patients with severe kidney disease. It should be used with caution in patients with mild to moderate kidney problems.
If you miss a dose of Tolvanix 15 mg Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Tolvanix 15 mg Tablet is not recommended for use during pregnancy and breastfeeding.
Common side effects are dizziness, headache, dry mouth, fatigue, diarrhoea, thirst and increased urge to urinate. Talk to your doctor if you experience these side effects persistently.
Store Tolvanix 15 mg Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Treatment with Tolvanix 15 mg Tablet should be started and re-started in a hospital or in the presence of a healthcare professional to monitor the sodium levels in your blood closely. Too rapid correction of hyponatremia (low sodium levels) may cause osmotic demyelination syndrome (serious nerve damage). Consult the doctor if you notice symptoms of osmotic demyelination syndrome such as difficulty speaking, feeling that food or drinks are getting stuck in your throat, difficulty swallowing, mood changes, drowsiness, confusion, body movements that are difficult to control, weakness of the arms or legs, or seizures.
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