Thrombosolv 1,500,000(Vhb)

Thrombosolv 1 belongs to the class of medicines called antifibrinolytic agents. It is used to dissolve blood clots that have formed in the blood vessels in various conditions such as Intravascular dissolution of thrombi and emboli in extensive deep vein thrombosis, Pulmonary embolism, Acute or subacute occlusion of peripheral arteries, Central retinal venous and Arterial thrombosis.

Thrombosolv 1 contains Streptokinase. Streptokinase creates a highly specific 1:1 enzymatic complex with plasminogen that transforms inactive plasminogen molecules into active plasmin. Plasmin destroys fibrin clots, as well as fibrinogen and other plasma proteins. This, in turn, causes the breakdown of blood clots.

Thrombosolv 1 should be administered to patients only in a hospital setting by an experienced healthcare professional. Thrombosolv 1 may cause certain common side effects, including allergic reactions, hypotension, tachycardia, bradycardia, hypotension, heart rate and rhythm disorders, angina pectoris, nausea, diarrhoea, epigastric pain, vomiting, headache, back pain, musculoskeletal pain, chills, fever, asthenia, elevations of serum transaminases and bilirubin. These side effects usually go away on their own. If you develop any other serious side effects, such as vision problems while using Thrombosolv 1, consult your doctor immediately.

Thrombosolv 1 is indicated in adults. Thrombosolv 1 is not recommended for children below 18 years of age as the safety and effectiveness were not established. Inform your doctor if you are pregnant or planning for pregnancy or breastfeeding since Thrombosolv 1 is contra-indicated in pregnancy, especially within the first 18 weeks of pregnancy. It is unknown whether Streptokinase is excreted in human milk. Breast milk should be discarded during the first 24 hours following thrombolytic therapy.

Thrombosolv 1 contains ‘Streptokinase’, which belongs to the class of anti-fibrinolytic agents. It acts by regulating the breakdown of blood clots in the body. It blocks the release and action of plasmin, an enzyme essential for the breakdown of clots in the blood. This effect helps to slow down abnormal bleeding.

• Haemorrhage at the injection site
• Ecchymoses (a discoloration of the skin)
• Gastrointestinal bleeding
• Genitourinary bleeding
• Epistaxis (nosebleed)
• Development of anti-streptokinase antibodies
• Allergic reactions
• Hypotension
• Tachycardia
• Bradycardia
• Hypotension
• Heart rate and rhythm disorders
• Angina pectoris
• Nausea
• Diarrhoea
• Epigastric pain
• Vomiting
• Headache
• Back pain
• Musculoskeletal pain
• Chills
• Fever
• Asthenia (abnormal physical weakness)
• Elevations of serum transaminases and bilirubin

Before taking Thrombosolv 1, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Usage of Thrombosolv 1 contraindicated to use in persons with certain medical conditions that cause risk of bleeding such as existing or recent internal haemorrhage (internal bleeding), recent cerebrovascular accident, intracranial or intraspinal surgery, intracranial neoplasm (brain tumour), recent head trauma, arteriovenous malformation (an abnormal connection between arteries and veins), neoplasm  (a cancerous tumour) with risk of bleeding, pancreas inflammation, severe liver or kidney damage and simultaneous or recent treatment with oral anticoagulants. So, let your doctor know about all your medical conditions, sensitivities, and all medications you are using.

• Ask your doctor about the preferred exercises to do based on your health condition.
• Stay hydrated and consume plenty of fluids. Fluids are necessary to maintain blood flow in your body.
• Consume fresh fruits and vegetables. Consult a dietitian and prepare a diet plan. Eating healthy can help you to recover faster.