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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 9:31 AM IST

Thiother 15mg Injection is used to prepare patients for bone marrow transplantation and reduce the risk of graft rejection; breast cancer, ovarian cancer, bladder cancer, serosal cavity neoplastic disease, and malignant effusions caused by cancerous tumours. It contains Thiotepa, which works by destroying bone marrow cells. This enables the transplantation of new bone marrow cells (haematopoietic progenitor cells), enabling the body to produce healthy blood cells. It helps treat cancer by slowing or stopping the growth of cancer cells in the body.

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Composition :

THIOTEPA-15MG

Manufacturer/Marketer :

Therdose Pharma Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Thiother 15mg Injection


Thiother 15mg Injection belongs to the group of medicines called alkylating agents used to prepare patients for bone marrow transplantation and reduce the risk of graft rejection. It is also indicated in the treatment of breast cancer, ovarian cancer, bladder cancer, and serosal cavity neoplastic disease. It is also used to treat malignant effusions caused by cancerous tumours.

Thiother 15mg Injection contains Thiotepa, which works by destroying bone marrow cells. This enables the transplantation of new bone marrow cells (haematopoietic progenitor cells), enabling the body to produce healthy blood cells. It helps treat cancer by slowing or stopping the growth of cancer cells in the body.

Thiother 15mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, Thiother 15mg Injection may cause nausea, vomiting, stomach pain, loss of appetite, headache, dizziness, hair loss, unusual tiredness or weakness, and pain at the site of injection. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Thiother 15mg Injection. Do not use Thiother 15mg Injection if you are pregnant or breastfeeding. Thiother 15mg Injection may cause blurred vision, dizziness, and headache; therefore, drive or operate machinery only if you are alert. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Thiother 15mg Injection

To prepare patients for bone marrow transplantation and reduce the risk of graft rejection; breast cancer, ovarian cancer, bladder cancer, serosal cavity neoplastic disease, and malignant effusions caused by cancerous tumours

Medicinal Benefits

Thiother 15mg Injection belongs to the group of medicines called alkylating agents used to prepare patients for bone marrow transplantation and reduce the risk of graft rejection. It is also indicated in the treatment of breast cancer, ovarian cancer, bladder cancer, and serosal cavity neoplastic disease. It is also used to treat malignant effusions (a condition when fluid collects in the lungs or around the heart) caused by cancerous tumours. Thiother 15mg Injection contains Thiotepa, which works by destroying bone marrow cells. This enables the transplantation of new bone marrow cells (haematopoietic progenitor cells), enabling the body to produce healthy blood cells. It helps treat cancer by slowing or stopping the growth of cancer cells in the body.

Side Effects of Thiother 15mg Injection

  • Nausea
  • Vomiting
  • Stomach pain
  • Pain at the site of injection
  • Headache
  • Loss of appetite
  • Diarrhoea

Directions for Use

Thiother 15mg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Thiother 15mg Injection if you are allergic to any of its components, if you are pregnant or breastfeeding, or if you are receiving yellow fever vaccination, live virus, or bacterial vaccines. Inform the doctor if you have a weak immune system, liver or kidney problems, heart or lung problems, seizures/fits, if you have previously received or will be receiving radiation (x-ray) therapy or other chemotherapy and if you have/had any medical conditions. Let the doctor know if you are taking any other medicines, including supplements and herbal products.

Therapeutic Class

ANTINEOPLASTIC

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables, fruits, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

How Thiother 15mg Injection Works

Thiother 15mg Injection contains Thiotepa, which works by destroying bone marrow cells. This enables the transplantation of new bone marrow cells (haematopoietic progenitor cells), enabling the body to produce healthy blood cells. It helps treat cancer by slowing or stopping the growth of cancer cells in the body.

What if I have taken an overdose of Thiother 15mg Injection

As Thiother 15mg Injection is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.
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Alcohol

Consult your doctor

It is not known if alcohol affects Thiother 15mg Injection. Please consult your doctor.

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Pregnancy

Unsafe

Thiother 15mg Injection should not be used during pregnancy as it can cause foetal harm. If you are pregnant, think you may be pregnant or are planning for pregnancy, you must inform the doctor before receiving Thiother 15mg Injection.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Thiother 15mg Injection.

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Driving

Caution

Thiother 15mg Injection may cause dizziness, headache, and blurred vision. Therefore, drive or operate heavy machinery only if you are alert.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Thiother 15mg Injection. Monitoring of patients with moderate to severe liver impairment for toxicity is advised.

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Kidney

Caution

If you have a history of kidney diseases, inform your doctor before receiving Thiother 15mg Injection. Monitoring of patients with moderate to severe kidney impairment for toxicity is advised.

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Children

Caution

Thiother 15mg Injection is safe for use in children for the prevention of graft rejection and bone marrow transplantation. Safety and effectiveness for the treatment of breast cancer, ovarian cancer, malignant effusions and bladder cancer have not been established in children.

Country of origin

India
Other Info - TH18321

Author Details

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FAQs

Thiother 15mg Injection is used to prepare patients for bone marrow transplantation and reduce the risk of graft rejection; breast cancer, ovarian cancer, bladder cancer, serosal cavity neoplastic disease, and malignant effusions caused by cancerous tumours.
Thiother 15mg Injection works by destroying bone marrow cells. This enables the transplantation of new bone marrow cells (haematopoietic progenitor cells), enabling the body to produce healthy blood cells. It helps treat cancer by slowing or stopping the growth of cancer cells in the body.
Thiother 15mg Injection may impair male and female fertility. It may stop sperm production in men and interfere with normal menstrual/period cycle in women. Consult the doctor if you have any concerns.
Concomitant use of Thiother 15mg Injection with live virus and bacteria vaccination and yellow fever vaccination is not advised as it may cause serious infections. Talk to the doctor if you are undergoing any vaccination.
Thiother 15mg Injection may increase the risk of infections or bleeding. Consult the doctor immediately if you notice unusual bleeding or bruising or any signs of infections such as fever, chills, pale skin, shortness of breath, tiredness, or mouth sores.

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