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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 9:31 AM IST

Thioplan 15 mg Injection is used to prepare patients for bone marrow transplantation and reduce the risk of graft rejection; breast cancer, ovarian cancer, bladder cancer, serosal cavity neoplastic disease, and malignant effusions caused by cancerous tumours. It contains Thiotepa, which works by destroying bone marrow cells. This enables the transplantation of new bone marrow cells (haematopoietic progenitor cells), enabling the body to produce healthy blood cells. It helps treat cancer by slowing or stopping the growth of cancer cells in the body.

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Composition :

THIOTEPA-15MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Thioplan 15 mg Injection


Thioplan 15 mg Injection belongs to the group of medicines called alkylating agents used to prepare patients for bone marrow transplantation and reduce the risk of graft rejection. It is also indicated in the treatment of breast cancer, ovarian cancer, bladder cancer, and serosal cavity neoplastic disease. It is also used to treat malignant effusions caused by cancerous tumours.

Thioplan 15 mg Injection contains Thiotepa, which works by destroying bone marrow cells. This enables the transplantation of new bone marrow cells (haematopoietic progenitor cells), enabling the body to produce healthy blood cells. It helps treat cancer by slowing or stopping the growth of cancer cells in the body.

Thioplan 15 mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, Thioplan 15 mg Injection may cause nausea, vomiting, stomach pain, loss of appetite, headache, dizziness, hair loss, unusual tiredness or weakness, and pain at the site of injection. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Thioplan 15 mg Injection. Do not use Thioplan 15 mg Injection if you are pregnant or breastfeeding. Thioplan 15 mg Injection may cause blurred vision, dizziness, and headache; therefore, drive or operate machinery only if you are alert. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Thioplan 15 mg Injection

To prepare patients for bone marrow transplantation and reduce the risk of graft rejection; breast cancer, ovarian cancer, bladder cancer, serosal cavity neoplastic disease, and malignant effusions caused by cancerous tumours

Medicinal Benefits

Thioplan 15 mg Injection belongs to the group of medicines called alkylating agents used to prepare patients for bone marrow transplantation and reduce the risk of graft rejection. It is also indicated in the treatment of breast cancer, ovarian cancer, bladder cancer, and serosal cavity neoplastic disease. It is also used to treat malignant effusions (a condition when fluid collects in the lungs or around the heart) caused by cancerous tumours. Thioplan 15 mg Injection contains Thiotepa, which works by destroying bone marrow cells. This enables the transplantation of new bone marrow cells (haematopoietic progenitor cells), enabling the body to produce healthy blood cells. It helps treat cancer by slowing or stopping the growth of cancer cells in the body.

Side Effects of Thioplan 15 mg Injection

  • Nausea
  • Vomiting
  • Stomach pain
  • Pain at the site of injection
  • Headache
  • Loss of appetite
  • Diarrhoea

Directions for Use

Thioplan 15 mg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Thioplan 15 mg Injection if you are allergic to any of its components, if you are pregnant or breastfeeding, or if you are receiving yellow fever vaccination, live virus, or bacterial vaccines. Inform the doctor if you have a weak immune system, liver or kidney problems, heart or lung problems, seizures/fits, if you have previously received or will be receiving radiation (x-ray) therapy or other chemotherapy and if you have/had any medical conditions. Let the doctor know if you are taking any other medicines, including supplements and herbal products.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

verifiedApollotooltip
ThiotepaCyclophosphamide
Severe
ThiotepaInfliximab
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables, fruits, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

How Thioplan 15 mg Injection Works

Thioplan 15 mg Injection contains Thiotepa, which works by destroying bone marrow cells. This enables the transplantation of new bone marrow cells (haematopoietic progenitor cells), enabling the body to produce healthy blood cells. It helps treat cancer by slowing or stopping the growth of cancer cells in the body.

What if I have taken an overdose of Thioplan 15 mg Injection

As Thioplan 15 mg Injection is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.
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Alcohol

Consult your doctor

It is not known if alcohol affects Thioplan 15 mg Injection. Please consult your doctor.

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Pregnancy

Unsafe

Thioplan 15 mg Injection should not be used during pregnancy as it can cause foetal harm. If you are pregnant, think you may be pregnant or are planning for pregnancy, you must inform the doctor before receiving Thioplan 15 mg Injection.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Thioplan 15 mg Injection.

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Driving

Caution

Thioplan 15 mg Injection may cause dizziness, headache, and blurred vision. Therefore, drive or operate heavy machinery only if you are alert.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Thioplan 15 mg Injection. Monitoring of patients with moderate to severe liver impairment for toxicity is advised.

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Kidney

Caution

If you have a history of kidney diseases, inform your doctor before receiving Thioplan 15 mg Injection. Monitoring of patients with moderate to severe kidney impairment for toxicity is advised.

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Children

Caution

Thioplan 15 mg Injection is safe for use in children for the prevention of graft rejection and bone marrow transplantation. Safety and effectiveness for the treatment of breast cancer, ovarian cancer, malignant effusions and bladder cancer have not been established in children.

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - THI0234

Author Details

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FAQs

Thioplan 15 mg Injection is used to prepare patients for bone marrow transplantation and reduce the risk of graft rejection; breast cancer, ovarian cancer, bladder cancer, serosal cavity neoplastic disease, and malignant effusions caused by cancerous tumours.
Thioplan 15 mg Injection works by destroying bone marrow cells. This enables the transplantation of new bone marrow cells (haematopoietic progenitor cells), enabling the body to produce healthy blood cells. It helps treat cancer by slowing or stopping the growth of cancer cells in the body.
Thioplan 15 mg Injection may impair male and female fertility. It may stop sperm production in men and interfere with normal menstrual/period cycle in women. Consult the doctor if you have any concerns.
Concomitant use of Thioplan 15 mg Injection with live virus and bacteria vaccination and yellow fever vaccination is not advised as it may cause serious infections. Talk to the doctor if you are undergoing any vaccination.
Thioplan 15 mg Injection may increase the risk of infections or bleeding. Consult the doctor immediately if you notice unusual bleeding or bruising or any signs of infections such as fever, chills, pale skin, shortness of breath, tiredness, or mouth sores.

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