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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
THIORIL 25MG TABLET is used to treat schizophrenia and bipolar disorder (manic depression). It contains Thioridazine which works by decreasing abnormal excitement in the brain. In some cases, this medicine may cause side effects such as sleepiness, dry mouth, abnormal voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

THIORIDAZINE-25MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About THIORIL 25MG TABLET

THIORIL 25MG TABLET is used to treat schizophrenia or psychosis and bipolar disorder (manic depression). Schizophrenia is characterized by hallucinations symptoms (seeing or hearing things that are not real) and delusions (wrong beliefs). Manic episodes of excitement or depression characterize bipolar disorder. THIORIL 25MG TABLET prevents the occurrence of these symptoms. 

THIORIL 25MG TABLET contains ‘Thioridazine,’ which is an antipsychotic drug. It acts by blocking dopamine, a neurotransmitter in the brain responsible for developing schizophrenia and bipolar disorder symptoms. THIORIL 25MG TABLET rebalances dopamine to improve thinking, mood and behaviour. It also blocks the other natural substance receptors in the brain, such as histamine and muscarinic, thereby preventing nausea and vomiting.

Take THIORIL 25MG TABLET as prescribed by your doctor. You are advised to take THIORIL 25MG TABLET as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side effects such as sleepiness, orthostatic hypotension (sudden lowering of blood pressure on standing), dry mouth, abnormality of voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor. Most of these side effects of THIORIL 25MG TABLET do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Do not take THIORIL 25MG TABLET if you are allergic to Thioridazine or any other ingredients present in it. Before taking THIORIL 25MG TABLET, talk to your doctor if you or your family have a history of blood clots, stroke or heart diseases and if you are above 65 years old and have a history of dementia (memory loss). THIORIL 25MG TABLET is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking THIORIL 25MG TABLET. It is not recommended for use in children under 1 year of age. THIORIL 25MG TABLET contains lactose, so it should not be given to people who are intolerant to some sugars. Please do not stop taking THIORIL 25MG TABLET without your doctor’s advice, as it may lead to withdrawal symptoms.

Uses of THIORIL 25MG TABLET

Treatment of Schizophrenia (mental illness), Bipolar disorder (manic depression).

Directions for Use

Take a THIORIL 25MG TABLET with a meal. You are advised to take THIORIL 25MG TABLET for as long as your doctor has prescribed, depending on your medical condition.

Medicinal Benefits

THIORIL 25MG TABLET works by helping to restore the balance of certain natural substances in the brain. The key action of THIORIL 25MG TABLET is to block the dopamine receptors (D2) in the brain and correct dopamine's overactivity. Altogether, THIORIL 25MG TABLET may help decrease hallucinations and help you think more clearly and positively about yourself, feel less agitated and take a more active part in everyday life. On the other hand, it also blocks histamine H1 and muscarinic M1 receptors in the vomiting centre, thereby preventing nausea and vomiting.

How THIORIL 25MG TABLET Works

THIORIL 25MG TABLET contains ‘Thioridazine,’ which is an antipsychotic drug. It acts by blocking dopamine, a neurotransmitter in the brain responsible for developing schizophrenia and bipolar disorder symptoms. THIORIL 25MG TABLET rebalances dopamine to improve thinking, mood and behaviour. It also blocks the other natural substance receptors in the brain, such as histamine and muscarinic, thereby preventing nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight

Side Effects of THIORIL 25MG TABLET

  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Sleepiness
  • Dryness in mouth
  • Urinary retention
  • Weight gain
  • Constipation
  • Muscle stiffness
  • Tremor

What if I have taken an overdose of THIORIL 25MG TABLET

Take THIORIL 25MG TABLET only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include blurred vision, drooling, nasal congestion, dry mouth, yellow eyes, vision colour changes, rapid/irregular/slow heart rate, high/low blood pressure, difficulty breathing, constipation, nausea, loss of appetite, dizziness, drowsiness, seizures, tremors, weakness, fever, muscle spasms/stiffness, low body temperature and difficulty walking. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take THIORIL 25MG TABLET if you are allergic (hypersensitive) to THIORIL 25MG TABLET or any ingredients present in it. Please consult your doctor before taking THIORIL 25MG TABLET if you are pregnant or planning to conceive and breastfeed. Elderly patients (above 65 years) with dementia-related psychosis (memory loss) treated with antipsychotic drugs are at increased risk of death. THIORIL 25MG TABLET injection is not recommended for treating patients with dementia-related psychosis. Do not abruptly stop taking the medication, as it may cause withdrawal symptoms, especially suicidal thoughts in young adults. If you are an asthmatic patient, please inform your doctor before taking a THIORIL 25MG TABLET injection, as it may cause life-threatening allergic-type reactions, including anaphylactic symptoms. Before taking THIORIL 25MG TABLET, talk to your doctor if you have a history of blood clots, alcohol or drug abuse, fits (seizures), Parkinson's disease, hypothyroidism (reduced activity of the thyroid gland), stroke or heart diseases and glaucoma (increased pressure in the eye).

Drug-Drug Interactions

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ThioridazineClobazam
Critical
ThioridazineEfavirenz
Critical

Drug-Drug Interactions

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ThioridazineClobazam
Critical
How does the drug interact with Thioril 25 Tablet 10's:
When Thioril 25 Tablet 10's is taken with Clobazam, may increase the blood levels of Thioril 25 Tablet 10's and cause an irregular heart rhythm.

How to manage the interaction:
Co-administration of Clobazam and Thioril 25 Tablet 10's can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ThioridazineEfavirenz
Critical
How does the drug interact with Thioril 25 Tablet 10's:
Taking Efavirenz with Thioril 25 Tablet 10's can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Efavirenz with Thioril 25 Tablet 10's together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ThioridazineHaloperidol
Critical
How does the drug interact with Thioril 25 Tablet 10's:
Combining Thioril 25 Tablet 10's and Haloperidol can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Thioril 25 Tablet 10's and Haloperidol together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
ThioridazineCelecoxib
Critical
How does the drug interact with Thioril 25 Tablet 10's:
Taking Thioril 25 Tablet 10's and celecoxib may increases the blood levels of Thioril 25 Tablet 10's which may cause irregular heart rhythm.

How to manage the interaction:
Taking Celecoxib with Thioril 25 Tablet 10's is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not stop using any medications without first talking to your doctor.
ThioridazineAmitriptyline
Critical
How does the drug interact with Thioril 25 Tablet 10's:
Amitriptyline and Thioril 25 Tablet 10's can enhance each other's effects when used together.

How to manage the interaction:
Although using Amitriptyline and Thioril 25 Tablet 10's together can cause an interaction, they can be used if prescribed by a doctor. If you have extreme sleepiness, confusion, anxiety, vomiting, vision problems, feeling hot or cold, sweating, muscle stiffness, fainting, fits, or coma, seek medical help. Do not discontinue any medications without consulting a doctor.
ThioridazineCarvedilol
Critical
How does the drug interact with Thioril 25 Tablet 10's:
Coadministration of Thioril 25 Tablet 10's with carvedilol can increase the risk of low blood pressure especially when standing up.

How to manage the interaction:
Taking Thioril 25 Tablet 10's with Carvedilol is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience any excessive sweating, palpitations, chest discomfort, or shortness of breath. Do not discontinue any medication without consulting a doctor.
ThioridazineCilostazol
Critical
How does the drug interact with Thioril 25 Tablet 10's:
When Cilostazol is taken with Thioril 25 Tablet 10's, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Using Thioril 25 Tablet 10's with Cilostazol is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ThioridazineIndapamide
Critical
How does the drug interact with Thioril 25 Tablet 10's:
Taking Indapamide with Thioril 25 Tablet 10's can increase the risk of heart problems.

How to manage the interaction:
Taking Thioril 25 Tablet 10's with Indapamide is not recommended, but can be taken if prescribed by the doctor.
ThioridazineParoxetine
Critical
How does the drug interact with Thioril 25 Tablet 10's:
Coadministration of Paroxetine with Thioril 25 Tablet 10's can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Thioril 25 Tablet 10's with Paroxetine is not recommended, but should be taken if advised by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ThioridazinePromethazine
Critical
How does the drug interact with Thioril 25 Tablet 10's:
Taking Promethazine with Thioril 25 Tablet 10's can increases the risk and severity of side effects such as extreme drowsiness, confusion, agitation, vomiting, blurred vision, feeling hot or cold, sweating, muscle stiffness, fainting, seizure (fits).

How to manage the interaction:
Taking Promethazine with Thioril 25 Tablet 10's is not recommended. Please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience uncontrollable movements of the mouth, tongue, cheeks, jaw, arms, or legs, fever, muscle rigidity, irregular pulse, or fast or irregular heartbeats. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Monitor your mood. Keep track of your mood regularly, including factors such as sleep, medicine and activities that can impact your mood. Exercise daily.
  • Exercise is nice to relieve tension. It can also avoid the weight gain that can be a side effect of your bipolar medication.
  • You may also practice calming techniques such as meditation and deep breathing exercises.
  • Get some normal sleep. Having enough sleep will help to stabilize your mood.
  • Eat a healthy diet. Certain foods may affect your mood more than others. Consider keeping a food log to track what you eat and how certain foods make you feel. Talk to your doctor or nutritionist about foods that may help stabilize your mood.
  • Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.
  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils and low-fat dairy products will help to keep a person in good health.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

THIORIL 25MG TABLET Substitute

Substitutes safety advice
  • Ridazin 25 Tablet 10's

    4.77per tablet
  • Repoise 25 mg Tablet 10's

    4.72per tablet
  • Multizine 25 mg Capsule 10's

    5.31per tablet
  • Delnil-25 Tablet 10's

    by AYUR

    4.86per tablet
  • Sycoril 25mg Tablet

    1.33per tablet
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Alcohol

Unsafe

Alcohol may worsen the condition and increase the risk of side effects while using THIORIL 25MG TABLET.

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Pregnancy

Caution

THIORIL 25MG TABLET is a category C pregnancy drug; using THIORIL 25MG TABLET during pregnancy may affect your unborn baby. Please consult your doctor before taking THIORIL 25MG TABLET if you are pregnant or planning to conceive.

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Breast Feeding

Caution

THIORIL 25MG TABLET is known to pass through the breast milk. So, it is recommended not to be taken during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if he/she feels that the benefits to you outweighs the risk.

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Driving

Unsafe

THIORIL 25MG TABLET may cause drowsiness, and dizziness in some cases, especially in elderly patients. If you are affected, do not drive or operate dangerous machinery after taking THIORIL 25MG TABLET.

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Liver

Caution

THIORIL 25MG TABLET should be used with caution if you have liver disease. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

THIORIL 25MG TABLET should be used with caution if you have kidney disease. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Caution

THIORIL 25MG TABLET is not recommended for children below 1 year of age. Children aged 1 and above can be given THIORIL 25MG TABLET but take it only in dose and duration prescribed by your doctor.

FAQs

THIORIL 25MG TABLET is used to treat schizophrenia or psychosis and bipolar disorder (manic depression).
THIORIL 25MG TABLET contains ‘Thioridazine,’ an antipsychotic drug that blocks dopamine, a neurotransmitter in the brain responsible for developing schizophrenia and bipolar disorder symptoms. THIORIL 25MG TABLET rebalances dopamine to improve thinking, mood, and behaviour.
You are not recommended to stop taking THIORIL 25MG TABLET without consulting your doctor. It may cause withdrawal symptoms such as palpitations (the sensation that the heart skipped a beat or extra beat), anxiety, confusion, difficulty sleeping and tremors. Therefore, take THIORIL 25MG TABLET for as long as your doctor has prescribed it, and if you experience any difficulty while taking THIORIL 25MG TABLET, please consult your doctor so that the dose may be gradually reduced.
THIORIL 25MG TABLET is not recommended for patients suffering from myasthenia gravis (severe muscle weakness) as it may worsen the condition. Therefore, inform your doctor if you have myasthenia gravis before taking THIORIL 25MG TABLET.
THIORIL 25MG TABLET may increase your body weight. So, while taking THIORIL 25MG TABLET keep a check on your body weight. Also, monitor your blood sugar and cholesterol levels.
THIORIL 25MG TABLET can decrease anxiety, irritability or agitation. However, you should consult a doctor before using THIORIL 25MG TABLET for any condition.
No, THIORIL 25MG TABLET should be taken with caution, especially in elderly patients with dementia, as THIORIL 25MG TABLET is known to cause an increased death rate in such patients.
THIORIL 25MG TABLET is known to cause changes in blood sugar levels. If you have diabetes and are taking THIORIL 25MG TABLET, please regularly monitor your blood sugar level to avoid any unpleasant side effects of THIORIL 25MG TABLET.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - THI0010

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