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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Themidol Injection 2 ml contains tramadol, which is used in the treatment of moderate to severe pain conditions. This medicine works by stopping the transmission of pain signals from nerves to the brain that are responsible for causing severe pain. Some of the common side effects include nausea, dizziness, headache, vomiting, dry mouth, drowsiness, constipation or sweating.
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Composition :

TRAMADOL-50MG

Manufacturer/Marketer :

Themis Medicare Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Themidol Injection 2 ml

Themidol Injection 2 ml is used in the treatment of moderate to severe pain. Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body). 

Themidol Injection 2 ml contains Tramadol, which works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thus, it inhibits the transmission of pain signals from nerves to the brain. Also, Themidol Injection 2 ml improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. 

Themidol Injection 2 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience nausea, dizziness, headache, vomiting, dry mouth, drowsiness, constipation or sweating. Most of these side effects of Themidol Injection 2 ml do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor. 

If you are known to be allergic to Themidol Injection 2 ml or any other medicines, please tell your doctor. Themidol Injection 2 ml is not recommended for children suffering from breathing problems. If you are pregnant or breastfeeding or have a history of fits, please inform your doctor before taking Themidol Injection 2 ml. Do not consume alcohol with Themidol Injection 2 ml as it may increase the risk of side effects. Avoid frequent or high doses as it may lead to addiction.

Uses of Themidol Injection 2 ml

Treatment of Moderate to severe pain

Directions for Use

Themidol Injection 2 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Themidol Injection 2 ml is a pain killer that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thus, it inhibits the transmission of pain signals from nerves to the brain. Also, Themidol Injection 2 ml improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Themidol Injection 2 ml is used to relieve pain after surgery, pain caused by an injury or illness. 

How Themidol Injection 2 ml Works

Themidol Injection 2 ml contains Tramadol, which works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thus, it inhibits the transmission of pain signals from nerves to the brain. Also, Themidol Injection 2 ml improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Themidol Injection 2 ml

  • Nausea
  • Dizziness
  • Headache
  • Vomiting
  • Dry mouth
  • Drowsiness
  • Constipation
  • Sweating

What if I have taken an overdose of Themidol Injection 2 ml

A health care professional administers Themidol Injection 2 ml in a hospital. Hence, the chances of overdose are less. Overdose of Themidol Injection 2 ml may causeLike other opioid overdose symptoms, tramadol overdose symptoms can include: cold, clammy skin; weak or limp muscles; respiratory depression (slow, shallow, or stopped breathing); signs of oversedation (e.g., sleepiness progressing to loss of consciousness or coma); and constricted or, in some cases, dilated pupils. Your doctor will take the necessary measures if an overdose is suspected.

Drug Warnings

If you are allergic to Tramadol or any other medicines, please tell your doctor. Themidol Injection 2 ml is not recommended for children suffering from breathing problems as it may worsen the symptoms of tramadol toxicity. If you are pregnant or breastfeeding or have a history of fits, please inform your doctor before taking Themidol Injection 2 ml. Do not consume alcohol with Themidol Injection 2 ml as it may increase the risk of side effects. Themidol Injection 2 ml may cause withdrawal symptoms if stopped abruptly. Avoid frequent or high doses as it may lead to addiction. 

Drug-Drug Interactions

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TramadolZiprasidone
Critical
TramadolAlvimopan
Critical

Drug-Drug Interactions

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TramadolZiprasidone
Critical
How does the drug interact with Themidol Injection 2 ml:
Co-administration of Ziprasidone with Themidol Injection 2 ml can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Themidol Injection 2 ml with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TramadolAlvimopan
Critical
How does the drug interact with Themidol Injection 2 ml:
Co-administration of Themidol Injection 2 ml with Alvimopan can make the side effects worse or more dangerous.

How to manage the interaction:
Taking Alvimopan with Themidol Injection 2 ml is not recommended, please consult your doctor before taking it.
TramadolRasagiline
Critical
How does the drug interact with Themidol Injection 2 ml:
Taking rasagiline with Themidol Injection 2 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Themidol Injection 2 ml with Rasagiline is not recommended, as it can lead to an interaction, but can be taken if advised by your doctor. However, if you experience any symptoms like severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
TramadolPhenelzine
Critical
How does the drug interact with Themidol Injection 2 ml:
Combining Phenelzine with Themidol Injection 2 ml can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Themidol Injection 2 ml with Phenelzine is not recommended, please consult your doctor before taking it.
TramadolLinezolid
Critical
How does the drug interact with Themidol Injection 2 ml:
Co-administration of Linezolid with Themidol Injection 2 ml can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Linezolid with Themidol Injection 2 ml is not recommended, consult a doctor before taking it. Consult a doctor if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not stop using any medications without talking to a doctor.
TramadolSafinamide
Critical
How does the drug interact with Themidol Injection 2 ml:
Taking Safinamide with Themidol Injection 2 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Themidol Injection 2 ml is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
TramadolTranylcypromine
Critical
How does the drug interact with Themidol Injection 2 ml:
Combining Tranylcypromine with Themidol Injection 2 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Themidol Injection 2 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TramadolTrazodone
Severe
How does the drug interact with Themidol Injection 2 ml:
Co-administration of Themidol Injection 2 ml with trazodone increases the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking trazodone with Themidol Injection 2 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TramadolPromethazine
Severe
How does the drug interact with Themidol Injection 2 ml:
Co-administration of Themidol Injection 2 ml with promethazine can increase the risk of seizures (fits).

How to manage the interaction:
Taking promethazine with Themidol Injection 2 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TramadolClonazepam
Severe
How does the drug interact with Themidol Injection 2 ml:
Co-administration of Clonazepam with Themidol Injection 2 ml may significantly lead to adverse effects such as respiratory difficulties (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Clonazepam and Themidol Injection 2 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercises such as swimming or walking. 
  • Drink plenty of water while taking Themidol Injection 2 ml to avoid dry mouth.
  • Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while taking Themidol Injection 2 ml.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

Yes

Therapeutic Class

NARCOTIC (OPIOID) ANALGESIC

Themidol Injection 2 ml Substitute

Substitutes safety advice
  • Tramazac Capsule 10's

    4.82per tablet
  • Contramal DT 50 mg Tablet 10's

    9.77per tablet
  • CEMADOL 50MG TABLET

    11.52per tablet
  • Contramal 50 mg Capsule 10's

    4.27per tablet
  • CONTRAMAL INJECTION 1ML

    20.70per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Themidol Injection 2 ml as it may cause drowsiness or increase the risk of side effects.

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Pregnancy

Caution

Themidol Injection 2 ml is usually not recommended during pregnancy as chronic use of Themidol Injection 2 ml during pregnancy may lead to withdrawal symptoms in newborns. However, please inform your doctor if you are pregnant before taking Themidol Injection 2 ml.

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Breast Feeding

Caution

Themidol Injection 2 ml may be excreted into breastmilk. Please consult your doctor. Your doctor will decide if Themidol Injection 2 ml can be given to breastfeeding mothers or not.

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Driving

Unsafe

Themidol Injection 2 ml may cause dizziness, blurred vision or drowsiness in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Themidol Injection 2 ml.

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Liver

Caution

Take Themidol Injection 2 ml with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Themidol Injection 2 ml with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Themidol Injection 2 ml should be used in doses recommended by a doctor for children above 1 year. It is not recommended for children with breathing problems as it may worsen tramadol toxicity symptoms.

FAQs

Themidol Injection 2 ml belongs to a class of medicines called opioid analgesics (pain killers) primarily used in the treatment of moderate to severe pain.
Themidol Injection 2 ml works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibiting the transmission of pain signals from nerves to the brain. Also, Themidol Injection 2 ml improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain.
Themidol Injection 2 ml may cause withdrawal symptoms such as irritability, anxiety, restlessness, difficulty in sleeping, palpitations (feeling your heartbeat), feeling sick, shivering, sweating, high blood pressure and shaking when you stop taking Themidol Injection 2 ml suddenly. Your doctor will reduce the dose gradually to avoid withdrawal symptoms.
Themidol Injection 2 ml may cause dry mouth as a common side effect. It is not necessary for everyone taking Themidol Injection 2 ml to experience this side effect. Drink plenty of water, suck on sugar candy or chew sugar-free gum to prevent dry mouth. If the condition worsens or persists, please consult a doctor.
Themidol Injection 2 ml may cause fits, especially when taken in high doses or if you have a history of fits. Therefore, it is recommended to inform your doctor if you ever had fits as it may increase the chance of getting fits.
You are not recommended to take Themidol Injection 2 ml with antidepressants (medicines used to treat depression) and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Themidol Injection 2 ml may increase the risk of fits. However, please consult a doctor before taking Themidol Injection 2 ml with other medicines.
Yes, Themidol Injection 2 ml may cause addiction especially if taken for a prolonged time. Therefore, Themidol Injection 2 ml should be given only for a short duration under strict medical supervision, particularly to patients who are susceptible to drug abuse. Take Themidol Injection 2 ml only as advised by a doctor as overuse or misuse of Themidol Injection 2 ml can lead to overdose or death.

Country of origin

India

Manufacturer/Marketer address

11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Other Info - THE0245

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