Thaloshil Capsule

Thaloshil Capsule is used to treat multiple myeloma. Thaloshil Capsule is also used to treat and prevent symptoms of erythema nodosum leprosum (ENL) and as maintenance therapy for the prevention and suppression of erythema nodosum leprosum recurrence. Multiple myeloma is a type of cancer that affects a type of white blood cells called plasma cells. ENL is an immune-mediated inflammatory complication of leprosy.
 
Thaloshil Capsule contains ‘Thalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Thereby, Thaloshil Capsule helps treat multiple myeloma.

You are advised to take Thaloshil Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as constipation, dizziness, sleepiness, tiredness, tremors, dysaesthesia (abnormal sensation), low blood cell count, nausea, vomiting, and swelling of hands and feet. Speak with your doctor if you experience any of these side effects persistently.
 
Do not take Thaloshil Capsule if you are pregnant as it might cause severe birth defects or the death of an unborn baby. Avoid taking Thaloshil Capsule if you are breastfeeding. Thaloshil Capsule may cause dizziness, sleepiness, and blurred vision, so drive only if you are alert. Thaloshil Capsule is not recommended for children below 18 years as safety and effectiveness have not been established. Avoid consuming alcohol along with Thaloshil Capsule as it could lead to increased dizziness. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Thaloshil Capsule belongs to the group of medicines called immunomodulatory agents used to treat multiple myeloma. Thaloshil Capsule works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Thereby, Thaloshil Capsule helps treat multiple myeloma. Thaloshil Capsule is also used to treat and prevent skin symptoms of erythema nodosum leprosum and as maintenance therapy for prevention and suppression of erythema nodosum leprosum recurrence.

• Constipation
• Dizziness
• Sleepiness
• Tiredness
• Tremor
• Dysaesthesia (abnormal sensation)
• Low blood cell count
• Swelling of hands and feet
• Nausea
• Vomiting
• Indigestion

Do not take Thaloshil Capsule if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Thaloshil Capsule if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Thaloshil Capsule if you are breastfeeding, as it is not unknown if it passes into breastmilk. Thaloshil Capsule may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Thaloshil Capsule is not recommended for children. Avoid consuming alcohol with Thaloshil Capsule as it could lead to increased dizziness and sleepiness. Thaloshil Capsule, when taken with dexamethasone, increases the risk of deep vein thrombosis and pulmonary embolism. Stop taking Thaloshil Capsule and consult a doctor immediately if you have think you are pregnant, if you have irregular periods, missed a period, have any change in menstrual bleeding, or if you have had sex without using two forms of birth control.

Drug-Drug Interactions: Thaloshil Capsule may interact with digitalis glycosides (digoxin), blood thinner (warfarin), bisphosphonate (pamidronate), anti-depressant (duloxetine), antipsychotics (aripiprazole, prochlorperazine), antibiotic (levofloxacin), pain killer (tramadol), anti-neoplastic agent (bortezomib), antiemetic (ondansetron), barbiturates (pentobarbital, phenobarbital, secobarbital), antihistamines, anxiolytics, hypnotics, opiate derivatives, anticholinesterases, herbal supplement used to treat depression (St. John’s wort) and beta-blockers.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have seizures, HIV infection, hypotension, neuropathy, or neutropenia (low levels of neutrophils).

• DIGOXIN
• WARFARIN
• DULOXETINE
• ARIPIPRAZOLE
• PROCHLORPERAZINE
• LEVOFLOXACIN
• TRAMADOL
• BORTEZOMIB
• ONDANSETRON
• PHENOBARBITAL
• SECOBARBITAL

• Eat a healthy diet and exercise regularly to maintain proper weight.

• Avoid smoking and alcohol consumption.

• Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.

• To prevent constipation, consume fibre rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

• Do not take Thaloshil Capsule if you are pregnant as it might cause severe birth defects or death of the unborn baby.

• Male patients taking Thaloshil Capsule must not donate semen and should use effective contraception during sexual activity even though they have undergone vasectomy.

• You must not donate blood while taking Thaloshil Capsule and for 4 weeks after discontinuing Thaloshil Capsule.

• Thaloshil Capsule might increase the risk of blood clots, so consult a doctor if you notice any symptoms such as chest pain, shortness of breath, swelling of arm or leg.

Multiple myeloma: Multiple myeloma is a type of cancer that affects a type of white blood cells called plasma cells. These cells collect in the bone marrow and divide uncontrollably, leading to kidney and bone damage. Symptoms include bone pain, loss of appetite, fever, and frequent infections. Generally, multiple myeloma cannot be cured, but the signs and symptoms can be reduced greatly or disappear after a period of time.

Erythema Nodosum Leprosum (ENL): It is an immune-mediated inflammatory complication of leprosy. It is a painful disorder characterised by tender bumps under the skin, fever, arthritis, and fatigue.