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Oncothal 100 mg Capsule 10's

Oncothal 100 mg Capsule 10's

Prescription drug
 Trailing icon
Consult Doctor

Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Oncothal 100 mg Capsule

Oncothal 100 mg Capsule is used to treat multiple myeloma. Oncothal 100 mg Capsule is also used to treat and prevent symptoms of erythema nodosum leprosum (ENL) and as maintenance therapy for the prevention and suppression of erythema nodosum leprosum recurrence. Multiple myeloma is a type of cancer that affects a type of white blood cells called plasma cells. ENL is an immune-mediated inflammatory complication of leprosy.
 
Oncothal 100 mg Capsule contains ‘Thalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Thereby, Oncothal 100 mg Capsule helps treat multiple myeloma.

You are advised to take Oncothal 100 mg Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as constipation, dizziness, sleepiness, tiredness, tremors, dysaesthesia (abnormal sensation), low blood cell count, nausea, vomiting, and swelling of hands and feet. Speak with your doctor if you experience any of these side effects persistently.
 
Do not take Oncothal 100 mg Capsule if you are pregnant as it might cause severe birth defects or the death of an unborn baby. Avoid taking Oncothal 100 mg Capsule if you are breastfeeding. Oncothal 100 mg Capsule may cause dizziness, sleepiness, and blurred vision, so drive only if you are alert. Oncothal 100 mg Capsule is not recommended for children below 18 years as safety and effectiveness have not been established. Avoid consuming alcohol along with Oncothal 100 mg Capsule as it could lead to increased dizziness. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Oncothal 100 mg Capsule

Treatment of Multiple myeloma, Erythema Nodosum Leprosum (ENL)

Medicinal Benefits

Oncothal 100 mg Capsule belongs to the group of medicines called immunomodulatory agents used to treat multiple myeloma. Oncothal 100 mg Capsule works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Thereby, Oncothal 100 mg Capsule helps treat multiple myeloma. Oncothal 100 mg Capsule is also used to treat and prevent skin symptoms of erythema nodosum leprosum and as maintenance therapy for prevention and suppression of erythema nodosum leprosum recurrence.

Directions for Use

Swallow Oncothal 100 mg Capsule as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Oncothal 100 mg Capsule

  • Constipation
  • Dizziness
  • Sleepiness
  • Tiredness
  • Tremor
  • Dysaesthesia (abnormal sensation)
  • Low blood cell count
  • Swelling of hands and feet
  • Nausea
  • Vomiting
  • Indigestion

Drug Warnings

Do not take Oncothal 100 mg Capsule if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Oncothal 100 mg Capsule if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Oncothal 100 mg Capsule if you are breastfeeding, as it is not unknown if it passes into breastmilk. Oncothal 100 mg Capsule may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Oncothal 100 mg Capsule is not recommended for children. Avoid consuming alcohol with Oncothal 100 mg Capsule as it could lead to increased dizziness and sleepiness. Oncothal 100 mg Capsule , when taken with dexamethasone, increases the risk of deep vein thrombosis and pulmonary embolism. Stop taking Oncothal 100 mg Capsule and consult a doctor immediately if you have think you are pregnant, if you have irregular periods, missed a period, have any change in menstrual bleeding, or if you have had sex without using two forms of birth control.

Drug Interactions

Drug-Drug Interactions: Oncothal 100 mg Capsule may interact with digitalis glycosides (digoxin), blood thinner (warfarin), bisphosphonate (pamidronate), anti-depressant (duloxetine), antipsychotics (aripiprazole, prochlorperazine), antibiotic (levofloxacin), pain killer (tramadol), anti-neoplastic agent (bortezomib), antiemetic (ondansetron), barbiturates (pentobarbital, phenobarbital, secobarbital), antihistamines, anxiolytics, hypnotics, opiate derivatives, anticholinesterases, herbal supplement used to treat depression (St. John’s wort) and beta-blockers.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have seizures, HIV infection, hypotension, neuropathy, or neutropenia (low levels of neutrophils).

Drug-Drug Interactions Checker List

  • DIGOXIN
  • WARFARIN
  • DULOXETINE
  • ARIPIPRAZOLE
  • PROCHLORPERAZINE
  • LEVOFLOXACIN
  • TRAMADOL
  • BORTEZOMIB
  • ONDANSETRON
  • PHENOBARBITAL
  • SECOBARBITAL

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.

  • To prevent constipation, consume fibre rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Special Advise

  • Do not take Oncothal 100 mg Capsule if you are pregnant as it might cause severe birth defects or death of the unborn baby.

  • Male patients taking Oncothal 100 mg Capsule must not donate semen and should use effective contraception during sexual activity even though they have undergone vasectomy.

  • You must not donate blood while taking Oncothal 100 mg Capsule and for 4 weeks after discontinuing Oncothal 100 mg Capsule .

  • Oncothal 100 mg Capsule might increase the risk of blood clots, so consult a doctor if you notice any symptoms such as chest pain, shortness of breath, swelling of arm or leg.

Disease/Condition Glossary

Multiple myeloma: Multiple myeloma is a type of cancer that affects a type of white blood cells called plasma cells. These cells collect in the bone marrow and divide uncontrollably, leading to kidney and bone damage. Symptoms include bone pain, loss of appetite, fever, and frequent infections. Generally, multiple myeloma cannot be cured, but the signs and symptoms can be reduced greatly or disappear after a period of time.

Erythema Nodosum Leprosum (ENL): It is an immune-mediated inflammatory complication of leprosy. It is a painful disorder characterised by tender bumps under the skin, fever, arthritis, and fatigue. 

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Oncothal 100 mg Capsule as it might cause increased sleepiness.

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Pregnancy

Unsafe

Oncothal 100 mg Capsule belongs to pregnancy category X. Oncothal 100 mg Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of child-bearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Oncothal 100 mg Capsule as it is unknown if Oncothal 100 mg Capsule passes into breastmilk.

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Driving

Unsafe

Oncothal 100 mg Capsule may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Oncothal 100 mg Capsule is not recommended for children below 18 years as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

D' Block, 3Rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)
Other Info - ONC0020

Author Details

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FAQs

Oncothal 100 mg Capsule belongs to the group of medicines called immunomodulatory agents used to treat multiple myeloma. Oncothal 100 mg Capsule is also used to treat and prevent symptoms of erythema nodosum leprosum (ENL) and as maintenance therapy for the prevention and suppression of erythema nodosum leprosum recurrence.
Oncothal 100 mg Capsule stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Thereby, Oncothal 100 mg Capsule helps treat multiple myeloma.
Do not stop taking Oncothal 100 mg Capsule on your own. You are advised to take Oncothal 100 mg Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Oncothal 100 mg Capsule .
Orthostatic hypotension could be a side-effect of Oncothal 100 mg Capsule . Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better.
No, it is not safe to father a child while taking Oncothal 100 mg Capsule . Thalidomide is present in the semen of male patients taking Oncothal 100 mg Capsule ; it could cause severe birth defects or death of the unborn baby. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Oncothal 100 mg Capsule and for at least 4weeks after discontinuing Oncothal 100 mg Capsule , even if you have undergone a successful vasectomy. Male patients taking Oncothal 100 mg Capsule must not donate semen.
Patients taking Oncothal 100 mg Capsule must not donate blood during the treatment with Oncothal 100 mg Capsule and for 4weeks after discontinuation of Oncothal 100 mg Capsule as the donated blood might be given to pregnant women whose foetus should not be exposed to thalidomide since it causes severe birth defects or death of the unborn baby.
People with multiple myeloma taking Oncothal 100 mg Capsule may have an increased risk for blood clots in veins, arteries, and lungs. The risk is higher if you take dexamethasone with Oncothal 100 mg Capsule for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.
Oncothal 100 mg Capsule may cause side effects such as nausea, vomiting, indigestion, dizziness, heartburn, constipation, tiredness, tremor or swelling of hands and feet. If these side effects persist or worsen, please consult your doctor.
If you forget to take a dose of Oncothal 100 mg Capsule , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the risk of side effects.

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