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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
TENOF 300MG TABLET is used to treat HIV infection and chronic hepatitis B. It contains Tenofovir disoproxil, which works by interfering with the normal working of enzymes (reverse transcriptase in HIV and DNA polymerase in HBV) that are essential for the production of viruses. It may cause common side effects such as diarrhoea, vomiting, nausea, bloating, flatulence, weakness, dizziness, headache, abdominal pain, and fatigue. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Hetero Drugs Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About TENOF 300MG TABLET

TENOF 300MG TABLET belongs to the group of medications called ‘antiretroviral drugs’ used to treat HIV infection and chronic hepatitis B. Human immunodeficiency virus (HIV) is a sexually transmitted infection that, over time, leads to acquired immunodeficiency syndrome (AIDS). Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

TENOF 300MG TABLET contains ‘Tenofovir disoproxil’, a ‘nucleotide reverse transcriptase inhibitor’ that works by interfering with the normal working of enzymes (reverse transcriptase in HIV and DNA polymerase in HBV) that are essential for the production of viruses. It effectively reduces the symptoms associated with HIV and chronic hepatitis B infection.

You should use this medicine as prescribed by your doctor. The common side-effects of TENOF 300MG TABLET are diarrhoea, being sick (vomiting), feeling sick (nausea), bloating, flatulence, weakness, dizziness, headache, abdominal pain, and fatigue. However, seek medical attention if the side effects persist or worsen.

Do not take TENOF 300MG TABLET if you are allergic to any of its contents. Patients should take necessary precautions to avoid infecting others. It should be used cautiously in patients with severe liver and kidney diseases. Consult a doctor immediately if you develop any new signs of infection while using this medicine. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of TENOF 300MG TABLET

Treatment of HIV, Chronic hepatitis B.

Directions for Use

Swallow the medicine as a whole with water. Do not crush or chew it.

Medicinal Benefits

TENOF 300MG TABLET contains ‘Tenofovir disoproxil’, which is an antiretroviral agent. It can effectively cause viral suppression in HIV and chronic hepatitis B. It acts on the enzymes that are essential for the replication of the virus. The enzyme essential for HIV replication is reverse transcriptase, and the enzyme for hepatitis B is DNA polymerase. TENOF 300MG TABLET blocks these enzymes and decreases the viral load in the blood.

How TENOF 300MG TABLET Works

TENOF 300MG TABLET contains ‘Tenofovir disoproxil’, a ‘nucleotide reverse transcriptase inhibitor’ that works by interfering with the normal working of enzymes (reverse transcriptase in HIV and DNA polymerase in HBV) that are essential for the production of viruses. It effectively reduces the symptoms associated with HIV and chronic hepatitis B infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TENOF 300MG TABLET

  • Diarrhoea
  • Vomiting
  • Nausea
  • Bloating
  • Flatulence
  • Weakness
  • Dizziness
  • Headache
  • Abdominal pain
  • Fatigue

What if I have taken an overdose of TENOF 300MG TABLET

Do not take more than the prescribed dose of TENOF 300MG TABLET as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take TENOF 300MG TABLET if you are allergic to ‘tenofovir disoproxil’ or any other contents present in it. It is contraindicated in adolescents with kidney failure. When this medicine is used in combination therapy for HIV, there is a risk of osteonecrosis (bone tissue death). There is a severe risk of fatal complications in patients with severe liver diseases, including chronic hepatitis B or C. Consult a doctor immediately if you develop any new signs of infection while using this medicine, as there is a chance of opportunistic infections (infection seen in patients with a weak immune system). Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Drug-Drug Interactions

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Tenofovir disoproxilStreptozocin
Critical
Tenofovir disoproxilDidanosine
Critical

Drug-Drug Interactions

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Tenofovir disoproxilStreptozocin
Critical
How does the drug interact with TENOF 300MG TABLET:
Combining TENOF 300MG TABLET and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking TENOF 300MG TABLET with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
Tenofovir disoproxilDidanosine
Critical
How does the drug interact with TENOF 300MG TABLET:
Coadministration of Didanosine with TENOF 300MG TABLET can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with TENOF 300MG TABLET is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilSulfasalazine
Severe
How does the drug interact with TENOF 300MG TABLET:
Coadministration of Sulfasalazine and TENOF 300MG TABLET can increase the risk of kidney problems.

How to manage the interaction:
Taking Sulfasalazine and TENOF 300MG TABLET together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir disoproxilFenoprofen
Severe
How does the drug interact with TENOF 300MG TABLET:
Coadministration of Fenoprofen and TENOF 300MG TABLET can increase the risk of kidney problems.

How to manage the interaction:
Taking Fenoprofen and TENOF 300MG TABLET together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, irregular urination, sudden weight gain or weight loss, muscle cramps, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir disoproxilCelecoxib
Severe
How does the drug interact with TENOF 300MG TABLET:
Coadministration of Celecoxib with TENOF 300MG TABLET may increase the risk of kidney problems.

How to manage the interaction:
Taking Celecoxib with TENOF 300MG TABLET together can possibly result in an interaction, but it can be taken if your doctor has advised it. Consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, or dizziness. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilLithium
Severe
How does the drug interact with TENOF 300MG TABLET:
Co-administration of Lithium carbonate with TENOF 300MG TABLET can increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction between TENOF 300MG TABLET and Lithium, you can take these medicines when prescribed by your doctor. Consult the doctor immediately if you experience symptoms such as vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, or weakness. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilCisplatin
Severe
How does the drug interact with TENOF 300MG TABLET:
Coadministration of Cisplatin and TENOF 300MG TABLET can increase the risk of kidney damage and reduce kidney function.

How to manage the interaction:
Taking Cisplatin and TENOF 300MG TABLET together can lead to an interaction, it can be taken when advised by your doctor. However, if you experience any symptoms like nausea, vomiting, irregular urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Tenofovir disoproxilMethotrexate
Severe
How does the drug interact with TENOF 300MG TABLET:
Coadministration of TENOF 300MG TABLET with Methotrexate may increase the levels and side effects of TENOF 300MG TABLET.

How to manage the interaction:
Although there is a possible interaction between TENOF 300MG TABLET and methotrexate, you can take these medicines when prescribed by your doctor. However, if you experience any symptoms such as vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, breathing difficulty, or dizziness, consult your doctor. Do not stop using any medications without consulting a doctor.
Tenofovir disoproxilBacitracin
Severe
How does the drug interact with TENOF 300MG TABLET:
Coadministration of Bacitracin with TENOF 300MG TABLET can increase the risk of developing kidney damage and reduced function.

How to manage the interaction:
Although there may be a possibility of interaction between TENOF 300MG TABLET and Bacitracin, it can be taken when prescribed by a doctor. If you experience any symptoms, contact the doctor immediately. Do not stop using any medications without talking to your doctor.
Tenofovir disoproxilPhenobarbital
Severe
How does the drug interact with TENOF 300MG TABLET:
Coadministration of Phenobarbital and TENOF 300MG TABLET can reduce the levels of TENOF 300MG TABLET, which can lead to low treatment outcomes.

How to manage the interaction:
Taking TENOF 300MG TABLET with Phenobarbital can result in an interaction, it can be taken when a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet with fresh fruits and vegetables.
  • Option for lean meat such as skinless chicken and fish. Limit processed and high-sugar foods.
  • Avoid acidic foods such as tomatoes, lemons, and oranges.
  • Limit alcohol intake and quit smoking.
  • Exercise regularly as it promotes both physical and mental health.
  • Take the necessary precautions to avoid the spread of infection to other people.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

TENOF 300MG TABLET Substitute

Substitutes safety advice
  • Tenvir 300 Tablet 30's

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  • Reviro 300mg Tablet 30's

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  • Tenocruz 300 mg Tablet 30's

    45.24per tablet
  • TENTIDE 300MG TABLET

    31.81per tablet
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Alcohol

Caution

Consuming alcohol while using TENOF 300MG TABLET may worsen the condition.

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Pregnancy

Caution

TENOF 300MG TABLET is a category B medicine. It should be used with caution in pregnant women.

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Breast Feeding

Caution

In the case of chronic hepatitis B, TENOF 300MG TABLET should be used in breastfeeding mothers only if clinically needed. Avoid breastfeeding if you have HIV.

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Driving

Caution

TENOF 300MG TABLET may cause dizziness. So, avoid driving if you feel dizzy.

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Liver

Caution

TENOF 300MG TABLET should be used with caution if you have liver disease. Dose adjustments may be necessary.

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Kidney

Caution

TENOF 300MG TABLET should not be used in adolescents with kidney failure. In other people with severe kidney diseases, TENOF 300MG TABLET is prescribed only if clinically needed.

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Children

Caution

TENOF 300MG TABLET should be used with caution in children below 12 years of age.

FAQs

TENOF 300MG TABLET is used to treat HIV infection and chronic hepatitis B.
TENOF 300MG TABLET works by blocking the action of enzymes that are essential for viral replication.
TENOF 300MG TABLET does not affect fertility. However, consult your doctor immediately if you develop any side effects while using TENOF 300MG TABLET.
TENOF 300MG TABLET should be taken as prescribed by your doctor. Abrupt stopping of this medicine may lead to resistance to other medications making the infection difficult to treat.
The chances of not having an HIV infection after taking the TENOF 300MG TABLET are high, when used correctly, and consult a doctor to confirm whether the further precautions are needed.
TENOF 300MG TABLET is used to treat HIV-1 virus so you can take the TENOF 300MG TABLET but if you are suffering with tuberculosis then you should consult the doctor. Inform about your medical conditions and take TENOF 300MG TABLET only if it is advised by your physician. Do not self-medicate.
In case of HIV-1 infection, TENOF 300MG TABLET may reduce the risk of passing the virus to others, but the chances of infecting others can still be there. In case of HBV infection, TENOF 300MG TABLET has not proven to reduce the risk of passing the virus to others.
TENOF 300MG TABLET is safe if used as advised by the doctor. It should be avoided by children under age of 12, but can be used by children of age group between 12-18 years.
Take TENOF 300MG TABLET preferably with food or as advised by the doctor. Swallow it with a glass of water. Do not crush or chew it.
You should take the TENOF 300MG TABLET for as long as it is prescribed by the doctor. Do not stop using it without the notice of the doctor until the course is completed as it may worsen your condition.
If you vomit within 1 hour of taking TENOF 300MG TABLET, then take the other tablet. If you vomit more than 1 hour after taking TENOF 300MG TABLET, then do not take another dose.
It is important not to miss a dose of TENOF 300MG TABLET. If you miss a dose, you should work out how long since you should have taken it, do not take a double dose to make up for a forgotten tablet. Wait and take next dose at the regular time.

Country of origin

INDIA

Manufacturer/Marketer address

7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad – 500 018. Telangana, INDIA
Other Info - TEN0071

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