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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 10, 2024 | 7:19 PM IST
Tenocruz 300 mg Tablet is used to treat HIV infection and chronic hepatitis B. It contains Tenofovir disoproxil, which works by interfering with the normal working of enzymes (reverse transcriptase in HIV and DNA polymerase in HBV) that are essential for the production of viruses. It may cause common side effects such as diarrhoea, vomiting, nausea, bloating, flatulence, weakness, dizziness, headache, abdominal pain, and fatigue. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer

Torrent Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Tenocruz 300 mg Tablet

Tenocruz 300 mg Tablet belongs to the group of medications called ‘antiretroviral drugs’ used to treat HIV infection and chronic hepatitis B. Human immunodeficiency virus (HIV) is a sexually transmitted infection that, over time, leads to acquired immunodeficiency syndrome (AIDS). Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

Tenocruz 300 mg Tablet contains ‘Tenofovir disoproxil’, a ‘nucleotide reverse transcriptase inhibitor’ that works by interfering with the normal working of enzymes (reverse transcriptase in HIV and DNA polymerase in HBV) that are essential for the production of viruses. It effectively reduces the symptoms associated with HIV and chronic hepatitis B infection.

You should use this medicine as prescribed by your doctor. The common side-effects of Tenocruz 300 mg Tablet are diarrhoea, being sick (vomiting), feeling sick (nausea), bloating, flatulence, weakness, dizziness, headache, abdominal pain, and fatigue. However, seek medical attention if the side effects persist or worsen.

Do not take Tenocruz 300 mg Tablet if you are allergic to any of its contents. Patients should take necessary precautions to avoid infecting others. It should be used cautiously in patients with severe liver and kidney diseases. Consult a doctor immediately if you develop any new signs of infection while using this medicine. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Tenocruz 300 mg Tablet

Treatment of HIV, Chronic hepatitis B.

Medicinal Benefits

Tenocruz 300 mg Tablet contains ‘Tenofovir disoproxil’, which is an antiretroviral agent. It can effectively cause viral suppression in HIV and chronic hepatitis B. It acts on the enzymes that are essential for the replication of the virus. The enzyme essential for HIV replication is reverse transcriptase, and the enzyme for hepatitis B is DNA polymerase. Tenocruz 300 mg Tablet blocks these enzymes and decreases the viral load in the blood.

Directions for Use

Swallow the medicine as a whole with water. Do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tenocruz 300 mg Tablet

  • Diarrhoea
  • Vomiting
  • Nausea
  • Bloating
  • Flatulence
  • Weakness
  • Dizziness
  • Headache
  • Abdominal pain
  • Fatigue

Drug Warnings

Do not take Tenocruz 300 mg Tablet if you are allergic to ‘tenofovir disoproxil’ or any other contents present in it. It is contraindicated in adolescents with kidney failure. When this medicine is used in combination therapy for HIV, there is a risk of osteonecrosis (bone tissue death). There is a severe risk of fatal complications in patients with severe liver diseases, including chronic hepatitis B or C. Consult a doctor immediately if you develop any new signs of infection while using this medicine, as there is a chance of opportunistic infections (infection seen in patients with a weak immune system). Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Drug Interactions

Drug-Drug Interactions: Tenocruz 300 mg Tablet may interact with a medication used to treat hepatitis B virus (adefovir dipivoxil), drugs used to treat bacterial infections (aminoglycosides, pentamidine, vancomycin), antifungal medicine (amphotericin B), antiviral drugs (didanosine, foscarnet, ganciclovir, and cidofovir), immunotherapy (interleukin-2), immunosuppressant (tacrolimus) and non-steroidal anti-inflammatory drugs (NSAIDs).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Tenocruz 300 mg Tablet should be used with caution in patients with severe liver or kidney diseases.

Drug-Drug Interactions Checker List

  • PENTAMIDINE
  • VANCOMYCIN
  • AMPHOTERICIN B
  • FOSCARNET
  • GANCICLOVIR
  • CIDOFOVIR
  • INTERLEUKIN-2
  • TACROLIMUS
  • DIDANOSINE
  • ADEFOVIR DIPIVOXIL

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a diet with fresh fruits and vegetables.
  • Option for lean meat such as skinless chicken and fish. Limit processed and high-sugar foods.
  • Avoid acidic foods such as tomatoes, lemons, and oranges.
  • Limit alcohol intake and quit smoking.
  • Exercise regularly as it promotes both physical and mental health.
  • Take the necessary precautions to avoid the spread of infection to other people.

Special Advise

Your doctor may regularly monitor liver function, kidney function, and bone density if you take Tenocruz 300 mg Tablet .

Disease/Condition Glossary

Human immunodeficiency syndrome (HIV): It is a virus that suppresses the immune system and causes acquired immunodeficiency syndrome (AIDS) over time. The suppression of immunity leads to the development of opportunistic infections. It is a life-long condition, and there is no permanent cure. The treatment (antiretroviral therapy) is given to suppress the infection.

Chronic Hepatitis B: It is a severe and long-term liver infection caused by the hepatitis B virus (HBV). It spreads by contact with infected body fluids. The symptoms of this condition are abdominal pain, dark urine, and yellowing of the eyes.

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Alcohol

Caution

Consuming alcohol while using Tenocruz 300 mg Tablet may worsen the condition.

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Pregnancy

Caution

Tenocruz 300 mg Tablet is a category B medicine. It should be used with caution in pregnant women.

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Breast Feeding

Caution

In the case of chronic hepatitis B, Tenocruz 300 mg Tablet should be used in breastfeeding mothers only if clinically needed. Avoid breastfeeding if you have HIV.

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Driving

Caution

Tenocruz 300 mg Tablet may cause dizziness. So, avoid driving if you feel dizzy.

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Liver

Caution

Tenocruz 300 mg Tablet should be used with caution if you have liver disease. Dose adjustments may be necessary.

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Kidney

Caution

Tenocruz 300 mg Tablet should not be used in adolescents with kidney failure. In other people with severe kidney diseases, Tenocruz 300 mg Tablet is prescribed only if clinically needed.

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Children

Caution

Tenocruz 300 mg Tablet should be used with caution in children below 12 years of age.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - TEN0914

Author Details

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FAQs

Tenocruz 300 mg Tablet is used to treat HIV infection and chronic hepatitis B.
Tenocruz 300 mg Tablet works by blocking the action of enzymes that are essential for viral replication.
Tenocruz 300 mg Tablet does not affect fertility. However, consult your doctor immediately if you develop any side effects while using Tenocruz 300 mg Tablet .
Tenocruz 300 mg Tablet should be taken as prescribed by your doctor. Abrupt stopping of this medicine may lead to resistance to other medications making the infection difficult to treat.
The chances of not having an HIV infection after taking the Tenocruz 300 mg Tablet are high, when used correctly, and consult a doctor to confirm whether the further precautions are needed.
Tenocruz 300 mg Tablet is used to treat HIV-1 virus so you can take the Tenocruz 300 mg Tablet but if you are suffering with tuberculosis then you should consult the doctor. Inform about your medical conditions and take Tenocruz 300 mg Tablet only if it is advised by your physician. Do not self-medicate.
In case of HIV-1 infection, Tenocruz 300 mg Tablet may reduce the risk of passing the virus to others, but the chances of infecting others can still be there. In case of HBV infection, Tenocruz 300 mg Tablet has not proven to reduce the risk of passing the virus to others.
Tenocruz 300 mg Tablet is safe if used as advised by the doctor. It should be avoided by children under age of 12, but can be used by children of age group between 12-18 years.
Take Tenocruz 300 mg Tablet preferably with food or as advised by the doctor. Swallow it with a glass of water. Do not crush or chew it.
You should take the Tenocruz 300 mg Tablet for as long as it is prescribed by the doctor. Do not stop using it without the notice of the doctor until the course is completed as it may worsen your condition.
If you vomit within 1 hour of taking Tenocruz 300 mg Tablet , then take the other tablet. If you vomit more than 1 hour after taking Tenocruz 300 mg Tablet , then do not take another dose.
It is important not to miss a dose of Tenocruz 300 mg Tablet . If you miss a dose, you should work out how long since you should have taken it, do not take a double dose to make up for a forgotten tablet. Wait and take next dose at the regular time.

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