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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Temozone 250 Capsule is an anti-cancer medicine used in the treatment of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma. This medicine works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Common side effects include loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever.
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Composition :

TEMOZOLOMIDE-250MG

Manufacturer/Marketer :

Zeelab Pharmacy Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Temozone 250 Capsule

Temozone 250 Capsule belongs to a class of medicines called 'anti-cancer/ antitumor agent', used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. A brain tumour is an uncontrolled and unregulated proliferation of cells in the brain. 

Temozone 250 Capsule contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Temozone 250 Capsule prevents tumours from growing.

Take Temozone 250 Capsule as prescribed. In some cases, Temozone 250 Capsule may cause loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever. Most of these side effects of Temozone 250 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are allergic to any of the contents. Temozone 250 Capsule is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Temozone 250 Capsule if you are pregnant or breastfeeding. Both women and men using Temozone 250 Capsule should use birth control to avoid pregnancy and fathering a child. It would be best not to drive and/or operate machines that require alertness as Temozone 250 Capsule may cause tiredness or sleepiness.

Uses of Temozone 250 Capsule

Treatment of Brain tumour

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Temozone 250 Capsule belongs to a class of medicines called anti-cancer/antitumor agents used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. It contains Temozolomide which works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Temozone 250 Capsule prevents tumours from growing.

How Temozone 250 Capsule Works

Temozone 250 Capsule contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Temozone 250 Capsule prevents tumours from growing.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Temozone 250 Capsule

  • Loss of appetite
  • Difficulty speaking
  • Headache
  • Vomiting
  • Nausea
  • Diarrhoea
  • Constipation
  • Rash
  • Hair loss
  • Tiredness
  • Infections
  • Fever
  • Increased blood sugar
  • Dry skin
  • Swelling
  • Weight loss/gain
  • Frequent urination

What if I have taken an overdose of Temozone 250 Capsule

Do not take more than the prescribed dose of Temozone 250 Capsule as it may cause overdose. The symptoms of overdose include unusual bleeding or bruising; red/black/tarry stools; red/dark brown/pink urine; coughing up or vomiting blood or material that looks like coffee grounds; sore throat, fever, ongoing congestion and cough, or other signs of infection. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Temozone 250 Capsule should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Temozone 250 Capsule. To treat your condition effectually, continue taking Temozone 250 Capsule for as long as your doctor has prescribed. Do not stop Temozone 250 Capsule midway under any circumstances without consulting the healthcare professional. Inform your doctor if you have an allergy to any components of Temozone 250 Capsule. Inform your doctor before taking Temozone 250 Capsule if you have allergic reactions, infections, lung, renal or hepatic disorders or low blood count (including neutropenia, lymphopenia, thrombocytopenia). Temozone 250 Capsule is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Temozone 250 Capsule if you are pregnant or breastfeeding. Both women and men using Temozone 250 Capsule should use birth control to avoid pregnancy or fathering a child. Do not receive any vaccinations or immunizations without your doctor's approval while taking Temozone 250 Capsule.

Drug-Drug Interactions

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TemozolomideEtanercept
Severe
TemozolomideThalidomide
Severe

Drug-Drug Interactions

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TemozolomideEtanercept
Severe
How does the drug interact with Temozone 250 Capsule:
Taking Temozone 250 Capsule with Etanercept can increase the risk of infections.

How to manage the interaction:
Although taking Temozone 250 Capsule and etanercept together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideThalidomide
Severe
How does the drug interact with Temozone 250 Capsule:
Taking thalidomide with Temozone 250 Capsule can increase the risk of blood clots.

How to manage the interaction:
Although taking Temozone 250 Capsule and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg. Do not stop using any medications without consulting doctor.
TemozolomideCladribine
Severe
How does the drug interact with Temozone 250 Capsule:
Using cladribine together with Temozone 250 Capsule may increase the risk of serious infections.

How to manage the interaction:
Although taking Temozone 250 Capsule and cladribine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideVoclosporin
Severe
How does the drug interact with Temozone 250 Capsule:
Taking voclosporin with Temozone 250 Capsule, may increase the risk of serious infections.

How to manage the interaction:
Although taking Temozone 250 Capsule and voclosporin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideClozapine
Severe
How does the drug interact with Temozone 250 Capsule:
Taking Temozone 250 Capsule with clozapine may increase the risk of serious infections.

How to manage the interaction:
Although taking Temozone 250 Capsule and clozapine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideFingolimod
Severe
How does the drug interact with Temozone 250 Capsule:
Taking Temozone 250 Capsule with Fingolimod can increase the risk of infection.

How to manage the interaction:
Although taking Temozone 250 Capsule and fingolimod together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideBaricitinib
Severe
How does the drug interact with Temozone 250 Capsule:
Taking baricitinib and Temozone 250 Capsule can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Temozone 250 Capsule if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
TemozolomideInfliximab
Severe
How does the drug interact with Temozone 250 Capsule:
Taking Temozone 250 Capsule with Infliximab can increase the risk of infections.

How to manage the interaction:
Although taking Temozone 250 Capsule and infliximab together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
TemozolomideAdalimumab
Severe
How does the drug interact with Temozone 250 Capsule:
Using adalimumab together with Temozone 250 Capsule may increase the risk of serious infections.

How to manage the interaction:
Although taking Temozone 250 Capsule and Adalimumab together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
TemozolomideAdalimumab
Severe
How does the drug interact with Temozone 250 Capsule:
Using adalimumab together with Temozone 250 Capsule may increase the risk of serious infections.

How to manage the interaction:
Although taking Temozone 250 Capsule and adalimumab together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Temozone 250 Capsule Substitute

Substitutes safety advice
  • Temoside 250 Capsule 5's

    1173.58per tablet
  • Gliotem 250 Capsule 1's

    3952.40per tablet
  • Acozolo-250 Capsule 5's

    4185.28per tablet
  • Temoaim-250 Capsule 5's

    3356.10per tablet
  • Temother 250 Capsule 5's

    3280.00per tablet
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Temozone 250 Capsule. It could lead to unpleasant side effects.

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Pregnancy

Caution

Please consult your doctor if you have any concerns about this. Temozone 250 Capsule should not be used during pregnancy unless prescribed by your doctor. Women of childbearing potential must use effective contraception during the treatment and for 6months after completion of the treatment.

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Breast Feeding

Unsafe

Temozone 250 Capsule should not be taken during breastfeeding as it passes into the breastmilk and may harm the baby.

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Driving

Caution

Temozone 250 Capsule may make you feel tired or sleepy. Drive and/or operate machines only if you are alert.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before using Temozone 250 Capsule. Your doctor will weigh the benefits and potential risks before prescribing Temozone 250 Capsule.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before using Temozone 250 Capsule. Your doctor will weigh the benefits and potential risks before prescribing Temozone 250 Capsule.

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Children

Caution

Safety and effectiveness of Temozone 250 Capsule in paediatric patients under the age of three have not been established.

FAQs

Temozone 250 Capsule belongs to a class of medicines called anti-cancer agents, used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years.
Temozone 250 Capsule works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Temozone 250 Capsule prevents tumours from growing.
Temozone 250 Capsule may cause permanent infertility. Male patients should use effective contraception and refrain from fathering a child for up to three months after treatment is completed. Prior to treatment, it is recommended to seek sperm conservation advice from your doctor.
Yes, Temozone 250 Capsule can cause neutropenia (low white blood cells count), lymphopenia (low lymphocytes count), thrombocytopenia (low platelet count). As a part of therapy, your doctor may monitor your blood profile.
Temozone 250 Capsule may lead to hyperglycemia (Increased blood sugar). Consult your doctor if you are diabetic. Regularly monitor your blood sugar levels while taking Temozone 250 Capsule.
The live vaccine may interact with Temozone 250 Capsule. Do not have vaccinations or immunisations without talking to your doctor first.
Other Info - TEMO450

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