Tametil 12.5mg Injection belongs to a class of antipsychotic medications called phenothiazines used to reduce symptoms of major mental disorders such as schizophrenia, and, acute mania. It is also used as a short-term treatment for anxiety. Additionally, it is used to treat symptoms of nausea and vomiting, and vertigo (dizziness) due to inner ear disorders such as Meniere’s syndrome or labyrinthitis. Schizophrenia is a mental disorder that affects the ability of a person to feel, think and behave properly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with one’s daily activities.

Tametil 12.5mg Injection contains Prochlorperazine which decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Tametil 12.5mg Injection has a calming effect on people suffering from anxiety or mania. Also, Tametil 12.5mg Injection works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Tametil 12.5mg Injection prevents nausea and vomiting. 

Tametil 12.5mg Injection will be administered by a healthcare professional. Do not self-administer. Some people may experience dry mouth, drowsiness, dizziness, blurred vision, and orthostatic hypotension (low blood pressure when standing up from sitting or lying down) as side effects of Tametil 12.5mg Injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

Do not take Tametil 12.5mg Injection if you are known to be allergic to it. Tametil 12.5mg Injection should be used with caution in elderly patients above 65 years as there is an increased risk of adverse effects. Tametil 12.5mg Injection is not recommended for children. Please inform your doctor if you are pregnant or breastfeeding before taking Tametil 12.5mg Injection. Avoid consumption of alcohol with Tametil 12.5mg Injection as it may increase adverse effects. Avoid exposure to direct sunlight while taking Tametil 12.5mg Injection as it may cause skin more sensitive to sunlight. If this injection solution comes in contact with your skin, it may cause dermatitis (a type of skin rash). 

Tametil 12.5mg Injection contains Prochlorperazine used to reduce symptoms of major mental disorders such as schizophrenia, acute mania, and short-term treatment of anxiety. It decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Tametil 12.5mg Injection has a calming effect on people suffering from anxiety or mania. Also, Tametil 12.5mg Injection works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Tametil 12.5mg Injection prevents nausea and vomiting. Additionally, it is used to treat symptoms of vertigo (dizziness) due to inner ear disorders such as Meniere’s syndrome or labyrinthitis.

• Dry mouth
• Drowsiness
• Dizziness
• Blurred vision
• Orthostatic hypotension (low blood pressure when standing up from sitting or lying down)

Do not take Tametil 12.5mg Injection if you are known to be allergic to Tametil 12.5mg Injection. Tametil 12.5mg Injection should be used with caution in elderly patients above 65 years as there is an increased risk of adverse effects. Tametil 12.5mg Injection is not recommended for children. Please inform your doctor if you are pregnant or breastfeeding before taking Tametil 12.5mg Injection. Avoid consumption of alcohol with Tametil 12.5mg Injection as it may increase adverse effects. Avoid exposure to direct sunlight while taking Tametil 12.5mg Injection as it may cause skin more sensitive to sunlight. If the injection solution comes in contact with your skin, it may cause dermatitis (a type of skin rash). If you have fits, depression, diabetes, pheochromocytoma (tumour on the adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Tametil 12.5mg Injection. 

Drug-Drug Interaction: Tametil 12.5mg Injection may interact with sedatives (phenobarbital), medicines used to treat migraine (clonidine, guanethidine), drugs used to reduce lung and saliva secretions (atropine, procyclidine), antidepressants (other phenothiazines, lithium), anticonvulsants, medicines used to treat iron poisoning (desferrioxamine), antiparkinson drug (levodopa), medicines used to treat asthma or to relieve stuffy nose or used in the eye drops (sympathomimetic drugs, adrenaline), antidiabetics, antacids, medicines used to control heartbeat (propranolol), medicines used in the treatment of Attention Deficit Hyperactivity Disorder (amphetamines), anticancer drugs and antibiotics. 

Drug-Food Interaction: Avoid intake of alcohol while taking Tametil 12.5mg Injection as it may increase side effects and cause breathing difficulties. 

Drug-Disease Interaction: If you have fits, depression, diabetes, pheochromocytoma (tumour on the adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), narrow-angle glaucoma, myasthenia gravis (muscle weakness), low blood levels of calcium, magnesium, and potassium, agranulocytosis (low number of white blood cells), underactive thyroid gland, glaucoma, very underweight, kidney, liver or heart problems or if you ever had a stroke or if you have a history of alcohol problems, inform your doctor before taking Tametil 12.5mg Injection.

• PHENOBARBITAL
• CLONIDINE
• GUANETHIDINE
• ATROPINE
• PROCYCLIDINE
• LITHIUM
• DESFERRIOXAMINE
• LEVODOPA
• ADRENALINE
• PROPRANOLOL
• AMPHETAMINE

• Eat a healthy low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
• Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off. 
• Include more cool beverages in your food, like flavoured gelatin and carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.
• Drink any other liquid at least 30 minutes after eating food. 
• If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.
• Avoid consumption of alcohol as it may increase adverse effects.

Avoid exposure to direct sunlight while taking Tametil 12.5mg Injection as it may cause skin more sensitive to sunlight.

Nausea and vomiting: Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). A receptor in our brain known as the chemoreceptor zone (CTZ) controls vomiting.

Schizophrenia: It is a mental disorder that affects the ability of a person to feel, think and behave clearly.

Mania: It is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Mania may occur due to lack of sleep or changes in sleep patterns, high levels of stress, and alcohol intake.

Anxiety: It is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with one’s daily activities. The symptoms of anxiety include feeling more stress than required for that event and a lack of ability to set aside restlessness and worry.

Meniere’s syndrome: It is a disorder of the inner ear that causes vertigo (spinning), hearing loss, and ringing in the ears.