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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Stemetil Injection 10 x 1 ml contains prochlorperazine used in the treatment of schizophrenia, acute mania and short-term treatment of anxiety, nausea and vomiting, vertigo (dizziness). It belongs to the class of antipsycotics which works by inhibiting dopamine receptors.
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Manufacturer/Marketer

Nicholas Piramal India Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Stemetil Injection 10 x 1 ml

Stemetil Injection 10 x 1 ml belongs to a class of antipsychotic medications called phenothiazines used to reduce symptoms of major mental disorders such as schizophrenia, and, acute mania. It is also used as a short-term treatment for anxiety. Additionally, it is used to treat symptoms of nausea and vomiting, and vertigo (dizziness) due to inner ear disorders such as Meniere’s syndrome or labyrinthitis. Schizophrenia is a mental disorder that affects the ability of a person to feel, think and behave properly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with one’s daily activities.

Stemetil Injection 10 x 1 ml contains Prochlorperazine which decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Stemetil Injection 10 x 1 ml has a calming effect on people suffering from anxiety or mania. Also, Stemetil Injection 10 x 1 ml works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Stemetil Injection 10 x 1 ml prevents nausea and vomiting. 

Stemetil Injection 10 x 1 ml will be administered by a healthcare professional. Do not self-administer. Some people may experience dry mouth, drowsiness, dizziness, blurred vision, and orthostatic hypotension (low blood pressure when standing up from sitting or lying down) as side effects of Stemetil Injection 10 x 1 ml . Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

Do not take Stemetil Injection 10 x 1 ml if you are known to be allergic to it. Stemetil Injection 10 x 1 ml should be used with caution in elderly patients above 65 years as there is an increased risk of adverse effects. Stemetil Injection 10 x 1 ml is not recommended for children. Please inform your doctor if you are pregnant or breastfeeding before taking Stemetil Injection 10 x 1 ml . Avoid consumption of alcohol with Stemetil Injection 10 x 1 ml as it may increase adverse effects. Avoid exposure to direct sunlight while taking Stemetil Injection 10 x 1 ml as it may cause skin more sensitive to sunlight. If this injection solution comes in contact with your skin, it may cause dermatitis (a type of skin rash). 

Uses of Stemetil Injection 10 x 1 ml

Treatment of Schizophrenia, acute mania and short-term treatment of anxiety, nausea and vomiting, vertigo (dizziness) due to inner ear problems such as Meniere's syndrome and labyrinthitis

Medicinal Benefits

Stemetil Injection 10 x 1 ml contains Prochlorperazine used to reduce symptoms of major mental disorders such as schizophrenia, acute mania, and short-term treatment of anxiety. It decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Stemetil Injection 10 x 1 ml has a calming effect on people suffering from anxiety or mania. Also, Stemetil Injection 10 x 1 ml works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Stemetil Injection 10 x 1 ml prevents nausea and vomiting. Additionally, it is used to treat symptoms of vertigo (dizziness) due to inner ear disorders such as Meniere’s syndrome or labyrinthitis.

Directions for Use

Stemetil Injection 10 x 1 ml will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Stemetil Injection 10 x 1 ml

  • Dry mouth
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Orthostatic hypotension (low blood pressure when standing up from sitting or lying down)

Drug Warnings

Do not take Stemetil Injection 10 x 1 ml if you are known to be allergic to Stemetil Injection 10 x 1 ml . Stemetil Injection 10 x 1 ml should be used with caution in elderly patients above 65 years as there is an increased risk of adverse effects. Stemetil Injection 10 x 1 ml is not recommended for children. Please inform your doctor if you are pregnant or breastfeeding before taking Stemetil Injection 10 x 1 ml . Avoid consumption of alcohol with Stemetil Injection 10 x 1 ml as it may increase adverse effects. Avoid exposure to direct sunlight while taking Stemetil Injection 10 x 1 ml as it may cause skin more sensitive to sunlight. If the injection solution comes in contact with your skin, it may cause dermatitis (a type of skin rash). If you have fits, depression, diabetes, pheochromocytoma (tumour on the adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Stemetil Injection 10 x 1 ml . 

Drug Interactions

Drug-Drug Interaction: Stemetil Injection 10 x 1 ml may interact with sedatives (phenobarbital), medicines used to treat migraine (clonidine, guanethidine), drugs used to reduce lung and saliva secretions (atropine, procyclidine), antidepressants (other phenothiazines, lithium), anticonvulsants, medicines used to treat iron poisoning (desferrioxamine), antiparkinson drug (levodopa), medicines used to treat asthma or to relieve stuffy nose or used in the eye drops (sympathomimetic drugs, adrenaline), antidiabetics, antacids, medicines used to control heartbeat (propranolol), medicines used in the treatment of Attention Deficit Hyperactivity Disorder (amphetamines), anticancer drugs and antibiotics. 

Drug-Food Interaction: Avoid intake of alcohol while taking Stemetil Injection 10 x 1 ml as it may increase side effects and cause breathing difficulties. 

Drug-Disease Interaction: If you have fits, depression, diabetes, pheochromocytoma (tumour on the adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), narrow-angle glaucoma, myasthenia gravis (muscle weakness), low blood levels of calcium, magnesium, and potassium, agranulocytosis (low number of white blood cells), underactive thyroid gland, glaucoma, very underweight, kidney, liver or heart problems or if you ever had a stroke or if you have a history of alcohol problems, inform your doctor before taking Stemetil Injection 10 x 1 ml .

Drug-Drug Interactions Checker List

  • PHENOBARBITAL
  • CLONIDINE
  • GUANETHIDINE
  • ATROPINE
  • PROCYCLIDINE
  • LITHIUM
  • DESFERRIOXAMINE
  • LEVODOPA
  • ADRENALINE
  • PROPRANOLOL
  • AMPHETAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off. 
  • Include more cool beverages in your food, like flavoured gelatin and carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.
  • Drink any other liquid at least 30 minutes after eating food. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.
  • Avoid consumption of alcohol as it may increase adverse effects.

Special Advise

Avoid exposure to direct sunlight while taking Stemetil Injection 10 x 1 ml as it may cause skin more sensitive to sunlight.

Disease/Condition Glossary

Nausea and vomiting: Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). A receptor in our brain known as the chemoreceptor zone (CTZ) controls vomiting.

Schizophrenia: It is a mental disorder that affects the ability of a person to feel, think and behave clearly.

Mania: It is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Mania may occur due to lack of sleep or changes in sleep patterns, high levels of stress, and alcohol intake.

Anxiety: It is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with one’s daily activities. The symptoms of anxiety include feeling more stress than required for that event and a lack of ability to set aside restlessness and worry.

Meniere’s syndrome: It is a disorder of the inner ear that causes vertigo (spinning), hearing loss, and ringing in the ears.  

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Alcohol

Unsafe

Avoid consumption of alcohol with Stemetil Injection 10 x 1 ml as it may increase the risk of adverse effects and cause severe breathing difficulties.

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Pregnancy

Caution

There is no information on the use of Stemetil Injection 10 x 1 ml during pregnancy. Please inform your doctor if you are pregnant before taking Stemetil Injection 10 x 1 ml . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Stemetil Injection 10 x 1 ml is not recommended to be used in breastfeeding unless absolutely necessary. Before taking this medication, discuss the risks and benefits with your doctor. Depending on your clinical condition, your doctor may prescribe a safer alternative.

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Driving

Caution

Stemetil Injection 10 x 1 ml may cause dizziness, drowsiness or blurred vision in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Stemetil Injection 10 x 1 ml .

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Liver

Caution

Take Stemetil Injection 10 x 1 ml with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Stemetil Injection 10 x 1 ml with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Stemetil Injection 10 x 1 ml is not recommended for children as safety and efficacy data are not available.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - STE0002

Author Details

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FAQs

Stemetil Injection 10 x 1 ml belongs to a class of antipsychotic medications called phenothiazines used to reduce symptoms of major mental disorders such as schizophrenia, and, acute mania. It is also used as a short-term treatment for anxiety.
Stemetil Injection 10 x 1 ml contains Prochlorperazine, an antipsychotic drug that decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Also, Stemetil Injection 10 x 1 ml works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Stemetil Injection 10 x 1 ml prevents nausea and vomiting.
Yes, Stemetil Injection 10 x 1 ml may be used to treat vertigo (spinning sensation) caused due to ear problems such as Meniere’s syndrome (a disorder of the inner ear).
Stemetil Injection 10 x 1 ml may cause photosensitivity (extreme sensitivity to sunlight) if used in high doses. Therefore, avoiding exposure to direct sunlight while taking Stemetil Injection 10 x 1 ml is recommended.
Stemetil Injection 10 x 1 ml should be used with caution in diabetes patients as it may increase blood sugar levels. Therefore, if you are diabetic, regular monitoring of blood sugar levels is recommended while on treatment with Stemetil Injection 10 x 1 ml .
Stemetil Injection 10 x 1 ml may cause low blood pressure in some patients while standing up suddenly from a sitting or lying down position and cause symptoms such as dizziness, sweating, nausea or fainting. Therefore, to avoid such side effects, you are recommended to get up slowly after lying down or sitting.

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