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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Stemetil Injection 10 x 1 ml contains prochlorperazine used in the treatment of schizophrenia, acute mania and short-term treatment of anxiety, nausea and vomiting, vertigo (dizziness). It belongs to the class of antipsycotics which works by inhibiting dopamine receptors.
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Manufacturer/Marketer :

Nicholas Piramal India Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Stemetil Injection 10 x 1 ml

Stemetil Injection 10 x 1 ml belongs to a class of antipsychotic medications called phenothiazines used to reduce symptoms of major mental disorders such as schizophrenia, and, acute mania. It is also used as a short-term treatment for anxiety. Additionally, it is used to treat symptoms of nausea and vomiting, and vertigo (dizziness) due to inner ear disorders such as Meniere’s syndrome or labyrinthitis. Schizophrenia is a mental disorder that affects the ability of a person to feel, think and behave properly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with one’s daily activities.

Stemetil Injection 10 x 1 ml contains Prochlorperazine which decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Stemetil Injection 10 x 1 ml has a calming effect on people suffering from anxiety or mania. Also, Stemetil Injection 10 x 1 ml works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Stemetil Injection 10 x 1 ml prevents nausea and vomiting. 

Stemetil Injection 10 x 1 ml will be administered by a healthcare professional. Do not self-administer. Some people may experience dry mouth, drowsiness, dizziness, blurred vision, and orthostatic hypotension (low blood pressure when standing up from sitting or lying down) as side effects of Stemetil Injection 10 x 1 ml . Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

Do not take Stemetil Injection 10 x 1 ml if you are known to be allergic to it. Stemetil Injection 10 x 1 ml should be used with caution in elderly patients above 65 years as there is an increased risk of adverse effects. Stemetil Injection 10 x 1 ml is not recommended for children. Please inform your doctor if you are pregnant or breastfeeding before taking Stemetil Injection 10 x 1 ml . Avoid consumption of alcohol with Stemetil Injection 10 x 1 ml as it may increase adverse effects. Avoid exposure to direct sunlight while taking Stemetil Injection 10 x 1 ml as it may cause skin more sensitive to sunlight. If this injection solution comes in contact with your skin, it may cause dermatitis (a type of skin rash). 

Uses of Stemetil Injection 10 x 1 ml

Treatment of Schizophrenia, acute mania and short-term treatment of anxiety, nausea and vomiting, vertigo (dizziness) due to inner ear problems such as Meniere's syndrome and labyrinthitis

Directions for Use

Stemetil Injection 10 x 1 ml will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Stemetil Injection 10 x 1 ml contains Prochlorperazine used to reduce symptoms of major mental disorders such as schizophrenia, acute mania, and short-term treatment of anxiety. It decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Stemetil Injection 10 x 1 ml has a calming effect on people suffering from anxiety or mania. Also, Stemetil Injection 10 x 1 ml works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Stemetil Injection 10 x 1 ml prevents nausea and vomiting. Additionally, it is used to treat symptoms of vertigo (dizziness) due to inner ear disorders such as Meniere’s syndrome or labyrinthitis.

How Stemetil Injection 10 x 1 ml Works

Stemetil Injection 10 x 1 ml contains Prochlorperazine which decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Stemetil Injection 10 x 1 ml has a calming effect on people suffering from anxiety or mania. Also, Stemetil Injection 10 x 1 ml works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Stemetil Injection 10 x 1 ml prevents nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Stemetil Injection 10 x 1 ml

  • Dry mouth
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Orthostatic hypotension (low blood pressure when standing up from sitting or lying down)

What if I have taken an overdose of Stemetil Injection 10 x 1 ml

Stemetil Injection 10 x 1 ml is administered by a healthcare professional in a hospital setting. Hence, the chances of overdose are less. An overdose may result in drowsiness and certain side effects, including temporary uncontrollable movements of the lips, eyes, head, and neck. Your doctor will take immediate necessary action if an overdose is suspected.

Drug Warnings

Do not take Stemetil Injection 10 x 1 ml if you are known to be allergic to Stemetil Injection 10 x 1 ml . Stemetil Injection 10 x 1 ml should be used with caution in elderly patients above 65 years as there is an increased risk of adverse effects. Stemetil Injection 10 x 1 ml is not recommended for children. Please inform your doctor if you are pregnant or breastfeeding before taking Stemetil Injection 10 x 1 ml . Avoid consumption of alcohol with Stemetil Injection 10 x 1 ml as it may increase adverse effects. Avoid exposure to direct sunlight while taking Stemetil Injection 10 x 1 ml as it may cause skin more sensitive to sunlight. If the injection solution comes in contact with your skin, it may cause dermatitis (a type of skin rash). If you have fits, depression, diabetes, pheochromocytoma (tumour on the adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Stemetil Injection 10 x 1 ml . 

Drug-Drug Interactions

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ProchlorperazineMetoclopramide
Critical
ProchlorperazineMesoridazine
Critical

Drug-Drug Interactions

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ProchlorperazineMetoclopramide
Critical
How does the drug interact with Stemetil Injection 10 x 1 ml :
Coadministration of metoclopramide and Stemetil Injection 10 x 1 ml can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Stemetil Injection 10 x 1 ml together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
ProchlorperazineMesoridazine
Critical
How does the drug interact with Stemetil Injection 10 x 1 ml :
Coadministration of mesoridazine and Stemetil Injection 10 x 1 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking mesoridazine with Stemetil Injection 10 x 1 ml is not recommended, but it can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
ProchlorperazineZiprasidone
Severe
How does the drug interact with Stemetil Injection 10 x 1 ml :
Taking Stemetil Injection 10 x 1 ml and Ziprasidone together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Stemetil Injection 10 x 1 ml and Ziprasidone, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without talking to a doctor.
ProchlorperazineArsenic trioxide
Severe
How does the drug interact with Stemetil Injection 10 x 1 ml :
Taking Arsenic trioxide and Stemetil Injection 10 x 1 ml together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Taking Arsenic trioxide with Stemetil Injection 10 x 1 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. You should contact your doctor immediately if you experience fainting, irregular heartbeats, prolonged diarrhoea or vomiting, sudden dizziness, lightheadedness, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
ProchlorperazineKetamine
Severe
How does the drug interact with Stemetil Injection 10 x 1 ml :
Coadministration of Stemetil Injection 10 x 1 ml with ketamine can increase the risk or severity of side effects.

How to manage the interaction:
Taking Stemetil Injection 10 x 1 ml with Ketamine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience dizziness, sleepiness, confusion, inability to concentrate, excessive sedation, and breathing problems. Do not stop using any medications without a doctor's advice.
ProchlorperazineSaquinavir
Severe
How does the drug interact with Stemetil Injection 10 x 1 ml :
Taking Stemetil Injection 10 x 1 ml and saquinavir together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Stemetil Injection 10 x 1 ml with Saquinavir can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
ProchlorperazineAnagrelide
Severe
How does the drug interact with Stemetil Injection 10 x 1 ml :
Taking Stemetil Injection 10 x 1 ml and Anagrelide together can increase the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Stemetil Injection 10 x 1 ml and anagrelide, but it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
ProchlorperazineTramadol
Severe
How does the drug interact with Stemetil Injection 10 x 1 ml :
Co-administration of tramadol with Stemetil Injection 10 x 1 ml can increase the risk of seizures(fits).

How to manage the interaction:
Taking Stemetil Injection 10 x 1 ml and tramadol together can possibly result in an interaction; it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ProchlorperazineBepridil
Severe
How does the drug interact with Stemetil Injection 10 x 1 ml :
Taking Stemetil Injection 10 x 1 ml and Bepridil together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Stemetil Injection 10 x 1 ml and Bepridil, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
ProchlorperazineDisopyramide
Severe
How does the drug interact with Stemetil Injection 10 x 1 ml :
Taking Stemetil Injection 10 x 1 ml with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Disopyramide with Stemetil Injection 10 x 1 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like a fast or irregular heartbeat, dizziness, fainting, shortness of breath, or severe diarrhoea or vomiting, it's important to call your doctor right away. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off. 
  • Include more cool beverages in your food, like flavoured gelatin and carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.
  • Drink any other liquid at least 30 minutes after eating food. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.
  • Avoid consumption of alcohol as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Stemetil Injection 10 x 1 ml Substitute

Substitutes safety advice
  • Tametil 12.5mg Injection

    17.46per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Stemetil Injection 10 x 1 ml as it may increase the risk of adverse effects and cause severe breathing difficulties.

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Pregnancy

Caution

There is no information on the use of Stemetil Injection 10 x 1 ml during pregnancy. Please inform your doctor if you are pregnant before taking Stemetil Injection 10 x 1 ml . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Stemetil Injection 10 x 1 ml is not recommended to be used in breastfeeding unless absolutely necessary. Before taking this medication, discuss the risks and benefits with your doctor. Depending on your clinical condition, your doctor may prescribe a safer alternative.

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Driving

Caution

Stemetil Injection 10 x 1 ml may cause dizziness, drowsiness or blurred vision in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Stemetil Injection 10 x 1 ml .

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Liver

Caution

Take Stemetil Injection 10 x 1 ml with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Stemetil Injection 10 x 1 ml with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Stemetil Injection 10 x 1 ml is not recommended for children as safety and efficacy data are not available.

FAQs

Stemetil Injection 10 x 1 ml belongs to a class of antipsychotic medications called phenothiazines used to reduce symptoms of major mental disorders such as schizophrenia, and, acute mania. It is also used as a short-term treatment for anxiety.
Stemetil Injection 10 x 1 ml contains Prochlorperazine, an antipsychotic drug that decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Also, Stemetil Injection 10 x 1 ml works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Stemetil Injection 10 x 1 ml prevents nausea and vomiting.
Yes, Stemetil Injection 10 x 1 ml may be used to treat vertigo (spinning sensation) caused due to ear problems such as Meniere’s syndrome (a disorder of the inner ear).
Stemetil Injection 10 x 1 ml may cause photosensitivity (extreme sensitivity to sunlight) if used in high doses. Therefore, avoiding exposure to direct sunlight while taking Stemetil Injection 10 x 1 ml is recommended.
Stemetil Injection 10 x 1 ml should be used with caution in diabetes patients as it may increase blood sugar levels. Therefore, if you are diabetic, regular monitoring of blood sugar levels is recommended while on treatment with Stemetil Injection 10 x 1 ml .
Stemetil Injection 10 x 1 ml may cause low blood pressure in some patients while standing up suddenly from a sitting or lying down position and cause symptoms such as dizziness, sweating, nausea or fainting. Therefore, to avoid such side effects, you are recommended to get up slowly after lying down or sitting.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - STE0002

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