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TALENDEP PLUS TABLET

TALENDEP PLUS TABLET

Not for online sale
Prescription drug
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Consult Doctor

Manufacturer/Marketer

Accardion Pharma Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About TALENDEP PLUS TABLET

TALENDEP PLUS TABLET belongs to the class of medications called ‘antidepressants’ used in the treatment of depression. Depression is a mood disorder that affects a person's daily life described as feelings of sadness, loss, or anger. These symptoms may interfere with your daily activities and affect your quality-of-life.

TALENDEP PLUS TABLET contains Imipramine and Diazepam. Imipramine is a tricyclic antidepressant. It works by increasing serotonin and noradrenalin levels, chemicals present in the brain responsible for energy, mood, and behavior. Diazepam is a benzodiazepine. It increases the levels of chemicals in the brain that produce a calming effect. Together, TALENDEP PLUS TABLET can effectively reduce the symptoms of depression.

You should take this medicine exactly as prescribed by the doctor. TALENDEP PLUS TABLET may cause side-effects such as drowsiness, fatigue (extreme tiredness), confusion, loss of coordination of body movements (ataxia), dryness in the mouth, constipation, difficulty in urination, difficulty passing urine, low blood pressure, decrease in sexual function, dilation of the pupil of the eye, vision problems, loss of appetite, and increased heart rate. These side-effects usually don’t require medical attention. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is not recommended to take TALENDEP PLUS TABLET if you are allergic to any contents of it. Do not take TALENDEP PLUS TABLET if you have severe liver disease, heart disease, mania (exaggerated behavior or hyperactivity), porphyria (an inherited blood disorder), difficulty passing urine, glaucoma (increased pressure inside the eye), severe breathing problems, phobia (a fear of particular object), myasthenia gravis (a condition in which muscles weaken), and sleep apnoea (a sleep disorder). Inform your doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 6 years of age. In children and young adults below 25 years, this medicine should be used with caution as it may increase suicidal tendencies and worsen depression. It should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. TALENDEP PLUS TABLET may cause drowsiness or blurred vision, so do not drive or operate heavy machinery if you are not fully alert.

Uses of TALENDEP PLUS TABLET

Treatment of Depression

Medicinal Benefits

TALENDEP PLUS TABLET is used to treat depression. It decreases the number of episodes of depression and also reduces the duration of each depressive episode. It improves mood, behavior, sleep and decreases anxiety. This medicine is prescribed for longer durations as it may take several weeks to improve your overall condition. TALENDEP PLUS TABLET is highly effective if taken regularly as per the doctor’s advice.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TALENDEP PLUS TABLET

  • Drowsiness
  • Fatigue (extreme tiredness)
  • Confusion
  • Headache
  • Dizziness
  • Slurred speech
  • Loss of coordination of body movements (ataxia)
  • Dryness in mouth
  • Constipation
  • Difficulty passing urine
  • Low blood pressure
  • Disturbances in sexual function
  • Dilation of the pupil of the eye
  • Vision problems
  • Loss of appetite
  • Increased heart rate
  • Changes in libido
  • Weight increase

Drug Warnings

It is not recommended to take monoamine oxidase inhibitors (MAOI) and TALENDEP PLUS TABLET simultaneously. You should wait for at least 14 days after discontinuing MAOI before using TALENDEP PLUS TABLET. Before taking TALENDEP PLUS TABLET, inform your doctor if you have any mental illness, personality disorder, are withdrawing from alcohol or any other medicines, enlarged prostate gland, overactive thyroid, fits, brain damage, poor blood circulation, severe kidney disease, tumors in the adrenal gland, panic attacks, long-term constipation, low levels of albumin, and a habit of smoke. Inform your doctor if you have suicidal thoughts as TALENDEP PLUS TABLET may worsen suicidal tendencies, especially in young adults. While taking TALENDEP PLUS TABLET, inform your doctor if you experience agitation, restlessness, nightmares, and hallucinations as this medicine may cause these side-effects, especially in children and the elderly. TALENDEP PLUS TABLET may cause total or partial memory loss when taken in high doses. TALENDEP PLUS TABLET may cause dependence, so it should be used for the shortest time possible in patients with a history of alcohol or drug abuse. After a few weeks of treatment, if the tablets are not working for you, inform your doctor immediately, as it can be a sign of tolerance. TALENDEP PLUS TABLET should not be used in combination with an opioid pain killer (buprenorphine). Concomitant use of these drugs may lead to serotonin syndrome (a life-threatening condition that causes high blood pressure and fast heart rate).

Drug Interactions

Drug-Drug Interactions: TALENDEP PLUS TABLET may interact with an opioid pain killer (buprenorphine), a medicine used to treat sleep problems (sodium oxybate), other antidepressants (fluvoxamine, fluoxetine, phenelzine, moclobemide, and Hypericum perforatum), antipsychotics (clozapine), medicines used to treat allergies, general anesthetics, medicines used to induce sleep (alprazolam), antibiotics (erythromycin and rifampicin), medicines used to relax muscles (suxamethonium and tubocurarin), strong pain killer (morphine), medicines used to treat fits or mental disorders (phenobarbital), medicines used to treat high blood pressure, antacids (cimetidine, omeprazole, and esomeprazole), a medicine used to treat alcohol addiction (disulfiram), medicines used to treat fits (phenytoin, carbamazepine, and sodium valproate), medicine used to treat asthma (theophylline), antivirals (atazanavir, ritonavir, efavirenz, indinavir, and zidovudine, etc.), antitubercular (isoniazid), oral contraceptives, steroid medicines, anesthetic (ketamine), medicines to treat nausea and vomiting (nabilone), and medicines used to treat heart conditions (diltiazem, verapamil, and quinidine, etc.).

Drug-Food Interactions: Alcohol may increase the risk of side-effects such as drowsiness.

Drug-Disease Interactions: TALENDEP PLUS TABLET should not be used in patients with severe liver disease, heart disease, mania (exaggerated behavior or hyperactivity), porphyria (an inherited blood disorder), difficulty passing urine, glaucoma (increased pressure inside the eye), severe breathing problems, phobia (a fear of particular object), myasthenia gravis (a condition in which muscles weaken), and sleep apnoea (a sleep disorder).

Drug-Drug Interactions Checker List

  • BUPRENORPHINE
  • SODIUM OXYBATE
  • FLUVOXAMINE
  • FLUOXETINE
  • PHENELZINE
  • MOCLOBEMIDE
  • HYPERICUM PERFORATUM
  • CLOZAPINE
  • ALPRAZOLAM
  • ERYTHROMYCIN
  • RIFAMPICIN
  • SUXAMETHONIUM
  • TUBOCURARINE
  • MORPHINE
  • PHENOBARBITAL
  • CIMETIDINE
  • OMEPRAZOLE
  • ESOMEPRAZOLE
  • DISULFIRAM
  • PHENYTOIN
  • CARBAMAZEPINE
  • SODIUM VALPROATE
  • THEOPHYLLINE
  • ATAZANAVIR
  • RITONAVIR
  • EFAVIRENZ
  • INDINAVIR
  • ZIDOVUDINE
  • ISONIAZID
  • KETAMINE
  • NABILONE
  • DILTIAZEM
  • VERAPAMIL
  • QUINIDINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables, and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help maintain neurotransmitter's proper maintenance.
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges, and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors, and follow the doctor’s treatment plan.

Special Advise

  • TALENDEP PLUS TABLET may reduce some blood cell counts and impair liver function. So, your doctor may monitor blood cell levels and liver function while using this medicine.
  • TALENDEP PLUS TABLET may cause problems with teeth, so your doctor may advise you to undergo regular dental check-ups throughout the treatment.
  • It is not recommended to abruptly stop TALENDEP PLUS TABLET, as it may cause withdrawal reactions such as irritability, excess sweating, nervousness, stomach upset, difficulty sleeping, and worsening of depression. Children may experience changes in behavior. Your doctor may gradually reduce the dose before completely stopping the medicine.
  • TALENDEP PLUS TABLET may cause orthostatic hypotension (sudden drop in blood pressure on standing). So, it is advised to rise-up slowly from a sitting or lying position.

Disease/Condition Glossary

Depression: It is a mood disorder characterized by the persistent feeling of sadness, unhappiness, anger, hopelessness, or loss that interferes with a person’s daily activities. Depression can also influence some chronic health conditions and relationships. In this condition, neurotransmitters (chemicals in the brain) such as dopamine, serotonin, and noradrenaline levels decrease, resulting in symptoms of depression. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drug use, and medical conditions. Counseling (psychotherapy) and antidepressants can be used to treat depression.

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Alcohol

Unsafe

Do not take alcohol while using TALENDEP PLUS TABLET as it can cause excessive drowsiness.

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Pregnancy

Unsafe

TALENDEP PLUS TABLET is not recommended for pregnant women as it may cause harmful effects to the unborn baby.

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Breast Feeding

Unsafe

TALENDEP PLUS TABLET may pass into breastmilk and cause harmful effects to the nursing baby. So, it is not recommended to use in breastfeeding mothers.

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Driving

Unsafe

TALENDEP PLUS TABLET may cause drowsiness and blurred vision, so do not drive or operate heavy machinery while using this medicine.

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Liver

Caution

TALENDEP PLUS TABLET should not be used in patients with severe liver diseases. It should be used with caution in patients with mild to moderate liver diseases, and the dose may have to be adjusted by your doctor.

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Kidney

Caution

TALENDEP PLUS TABLET should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

TALENDEP PLUS TABLET should not be used in children less than 6 years of age. In children above 6 years, this medicine should be used only if clinically needed.

Country of origin

India
Other Info - TAL0026

Author Details

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FAQs

TALENDEP PLUS TABLET is used in the treatment of depression.
TALENDEP PLUS TABLET contains Imipramine and Diazepam. Imipramine is a tricyclic antidepressant. It works by increasing serotonin and noradrenalin levels, chemicals present in the brain responsible for energy, mood, and behavior. Diazepam is a benzodiazepine. It increases the levels of chemicals in the brain that produce a calming effect. Together, TALENDEP PLUS TABLET can effectively reduce the symptoms of depression.
TALENDEP PLUS TABLET may cause side-effects such as drowsiness, fatigue (extreme tiredness), confusion, loss of coordination of body movements (ataxia), dryness in the mouth, constipation, difficulty in urination, difficulty passing urine, low blood pressure, decrease in sexual function, dilation of the pupil of the eye, vision problems, loss of appetite, and increased heart rate. These side-effects usually don’t require medical attention. However, if any of these side-effects persist or get worse, inform your doctor immediately.
TALENDEP PLUS TABLET can be addictive or habit-forming if taken for prolonged periods. So, it is advised to take TALENDEP PLUS TABLET only for a duration as intended by the doctor.
It is not advised to take other antidepressants, especially monoamine oxidase inhibitors (MAOI) such as phenelzine and moclobemide, while using TALENDEP PLUS TABLET. It may lead to unwanted effects. The doctor may advise you to wait for at least 14 days after discontinuing MAOI if you have been prescribed TALENDEP PLUS TABLET.
TALENDEP PLUS TABLET may affect blood sugar levels. So, it is necessary to inform your doctor that you have diabetes before taking this medicine.
TALENDEP PLUS TABLET may alter blood count, impair liver function, and cause problems with teeth. Therefore, you should regularly monitor blood cell levels, liver function tests and undergo dental check-ups while taking this medicine.

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