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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:47 PM IST
Toframine-2/25 mg Tablet is used to treat depression. It contains Imipramine and Diazepam which work by increasing certain chemicals in the brain that produce a calming effect. In some cases, this medicine may cause side effects such as drowsiness, fatigue, confusion, dry mouth, constipation, vision problems, and loss of appetite. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer :

Psyco Remedies Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Toframine-2/25 mg Tablet

Toframine-2/25 mg Tablet belongs to the class of medications called ‘antidepressants’ used in the treatment of depression. Depression is a mood disorder that affects a person's daily life described as feelings of sadness, loss, or anger. These symptoms may interfere with your daily activities and affect your quality-of-life.

Toframine-2/25 mg Tablet contains Imipramine and Diazepam. Imipramine is a tricyclic antidepressant. It works by increasing serotonin and noradrenalin levels, chemicals present in the brain responsible for energy, mood, and behavior. Diazepam is a benzodiazepine. It increases the levels of chemicals in the brain that produce a calming effect. Together, Toframine-2/25 mg Tablet can effectively reduce the symptoms of depression.

You should take this medicine exactly as prescribed by the doctor. Toframine-2/25 mg Tablet may cause side-effects such as drowsiness, fatigue (extreme tiredness), confusion, loss of coordination of body movements (ataxia), dryness in the mouth, constipation, difficulty in urination, difficulty passing urine, low blood pressure, decrease in sexual function, dilation of the pupil of the eye, vision problems, loss of appetite, and increased heart rate. These side-effects usually don’t require medical attention. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is not recommended to take Toframine-2/25 mg Tablet if you are allergic to any contents of it. Do not take Toframine-2/25 mg Tablet if you have severe liver disease, heart disease, mania (exaggerated behavior or hyperactivity), porphyria (an inherited blood disorder), difficulty passing urine, glaucoma (increased pressure inside the eye), severe breathing problems, phobia (a fear of particular object), myasthenia gravis (a condition in which muscles weaken), and sleep apnoea (a sleep disorder). Inform your doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 6 years of age. In children and young adults below 25 years, this medicine should be used with caution as it may increase suicidal tendencies and worsen depression. It should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. Toframine-2/25 mg Tablet may cause drowsiness or blurred vision, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Toframine-2/25 mg Tablet

Treatment of Depression

Medicinal Benefits

Toframine-2/25 mg Tablet is used to treat depression. It decreases the number of episodes of depression and also reduces the duration of each depressive episode. It improves mood, behavior, sleep and decreases anxiety. This medicine is prescribed for longer durations as it may take several weeks to improve your overall condition. Toframine-2/25 mg Tablet is highly effective if taken regularly as per the doctor’s advice.

Side Effects of Toframine-2/25 mg Tablet

  • Drowsiness
  • Fatigue (extreme tiredness)
  • Confusion
  • Headache
  • Dizziness
  • Slurred speech
  • Loss of coordination of body movements (ataxia)
  • Dryness in mouth
  • Constipation
  • Difficulty passing urine
  • Low blood pressure
  • Disturbances in sexual function
  • Dilation of the pupil of the eye
  • Vision problems
  • Loss of appetite
  • Increased heart rate
  • Changes in libido
  • Weight increase

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

It is not recommended to take monoamine oxidase inhibitors (MAOI) and Toframine-2/25 mg Tablet simultaneously. You should wait for at least 14 days after discontinuing MAOI before using Toframine-2/25 mg Tablet . Before taking Toframine-2/25 mg Tablet , inform your doctor if you have any mental illness, personality disorder, are withdrawing from alcohol or any other medicines, enlarged prostate gland, overactive thyroid, fits, brain damage, poor blood circulation, severe kidney disease, tumors in the adrenal gland, panic attacks, long-term constipation, low levels of albumin, and a habit of smoke. Inform your doctor if you have suicidal thoughts as Toframine-2/25 mg Tablet may worsen suicidal tendencies, especially in young adults. While taking Toframine-2/25 mg Tablet , inform your doctor if you experience agitation, restlessness, nightmares, and hallucinations as this medicine may cause these side-effects, especially in children and the elderly. Toframine-2/25 mg Tablet may cause total or partial memory loss when taken in high doses. Toframine-2/25 mg Tablet may cause dependence, so it should be used for the shortest time possible in patients with a history of alcohol or drug abuse. After a few weeks of treatment, if the tablets are not working for you, inform your doctor immediately, as it can be a sign of tolerance. Toframine-2/25 mg Tablet should not be used in combination with an opioid pain killer (buprenorphine). Concomitant use of these drugs may lead to serotonin syndrome (a life-threatening condition that causes high blood pressure and fast heart rate).

Therapeutic Class

ANTIDEPRESSANT

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables, and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help maintain neurotransmitter's proper maintenance.
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges, and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors, and follow the doctor’s treatment plan.

Habit Forming

No

How Toframine-2/25 mg Tablet Works

Toframine-2/25 mg Tablet contains Imipramine and Diazepam. Imipramine is a tricyclic antidepressant. It works by increasing serotonin and noradrenalin levels, chemicals present in the brain responsible for energy, mood, and behavior. Diazepam is a benzodiazepine. It increases the levels of chemicals in the brain that produce a calming effect. Together, Toframine-2/25 mg Tablet can effectively reduce the symptoms of depression.

What if I have taken an overdose of Toframine-2/25 mg Tablet

Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.
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Alcohol

Unsafe

Do not take alcohol while using Toframine-2/25 mg Tablet as it can cause excessive drowsiness.

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Pregnancy

Unsafe

Toframine-2/25 mg Tablet is not recommended for pregnant women as it may cause harmful effects to the unborn baby.

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Breast Feeding

Unsafe

Toframine-2/25 mg Tablet may pass into breastmilk and cause harmful effects to the nursing baby. So, it is not recommended to use in breastfeeding mothers.

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Driving

Unsafe

Toframine-2/25 mg Tablet may cause drowsiness and blurred vision, so do not drive or operate heavy machinery while using this medicine.

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Liver

Caution

Toframine-2/25 mg Tablet should not be used in patients with severe liver diseases. It should be used with caution in patients with mild to moderate liver diseases, and the dose may have to be adjusted by your doctor.

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Kidney

Caution

Toframine-2/25 mg Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Toframine-2/25 mg Tablet should not be used in children less than 6 years of age. In children above 6 years, this medicine should be used only if clinically needed.

Country of origin

India

Manufacturer/Marketer address

Sco-58, 59, Sector-17D Chandigarh-160017
Other Info - TOF0035

Author Details

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FAQs

Toframine-2/25 mg Tablet is used in the treatment of depression.
Toframine-2/25 mg Tablet contains Imipramine and Diazepam. Imipramine is a tricyclic antidepressant. It works by increasing serotonin and noradrenalin levels, chemicals present in the brain responsible for energy, mood, and behavior. Diazepam is a benzodiazepine. It increases the levels of chemicals in the brain that produce a calming effect. Together, Toframine-2/25 mg Tablet can effectively reduce the symptoms of depression.
Toframine-2/25 mg Tablet may cause side-effects such as drowsiness, fatigue (extreme tiredness), confusion, loss of coordination of body movements (ataxia), dryness in the mouth, constipation, difficulty in urination, difficulty passing urine, low blood pressure, decrease in sexual function, dilation of the pupil of the eye, vision problems, loss of appetite, and increased heart rate. These side-effects usually don’t require medical attention. However, if any of these side-effects persist or get worse, inform your doctor immediately.
Toframine-2/25 mg Tablet can be addictive or habit-forming if taken for prolonged periods. So, it is advised to take Toframine-2/25 mg Tablet only for a duration as intended by the doctor.
It is not advised to take other antidepressants, especially monoamine oxidase inhibitors (MAOI) such as phenelzine and moclobemide, while using Toframine-2/25 mg Tablet . It may lead to unwanted effects. The doctor may advise you to wait for at least 14 days after discontinuing MAOI if you have been prescribed Toframine-2/25 mg Tablet .
Toframine-2/25 mg Tablet may affect blood sugar levels. So, it is necessary to inform your doctor that you have diabetes before taking this medicine.
Toframine-2/25 mg Tablet may alter blood count, impair liver function, and cause problems with teeth. Therefore, you should regularly monitor blood cell levels, liver function tests and undergo dental check-ups while taking this medicine.

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