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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Tadafil-D Tablet is used to treat erectile dysfunction (impotence) and premature ejaculation in men. It contains Tadalafil and Dapoxetine, which relaxes smooth muscles and widens blood vessels in the penis. Thereby, it helps to treat erectile dysfunction and symptoms of an enlarged prostate. Also, it improves control over ejaculation and hence increases the time taken to ejaculate. It may cause side effects such as nausea, dizziness, vomiting, dryness in the mouth, indigestion, nosebleeds, headache, and flushing (sense of warmth in the face, ears, neck, and trunk). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

D D Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Tadafil-D Tablet

Tadafil-D Tablet is a combination drug containing 'impotent agents', primarily used to treat erectile dysfunction (impotence) and premature ejaculation in men. Erectile dysfunction is the inability to keep a hard and erect penis suitable for sexual activity. Premature ejaculation is a very common sexual complaint. It is a problem in which a man ejaculates sooner than his partner during sexual intercourse.

Tadafil-D Tablet contains Tadalafil and Dapoxetine. Tadalafil works by inhibiting the phosphodiesterase enzyme, which leads to the breakdown of cGMP and causes relaxation of smooth muscles and vasodilation (widening) of blood vessels in the penis. Thereby, it helps to treat erectile dysfunction and symptoms of an enlarged prostate. Dapoxetine works by increasing the serotonin level in nerves, which improves control over ejaculation and hence increases the time taken to ejaculate.

Take Tadafil-D Tablet as prescribed by your doctor. You are advised to take Tadafil-D Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience nausea, dizziness, vomiting, dryness in the mouth, indigestion, nosebleeds, headache, and flushing (sense of warmth in the face, ears, neck, and trunk). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Tadafil-D Tablet if you take nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension), or alpha-blockers if you have heart problems or stroke, low or uncontrolled high blood pressure. Tadafil-D Tablet is not intended for use in women. Tadafil-D Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Tadafil-D Tablet should not be given to children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and the medicines you are taking to avoid unpleasant side effects. Do not take Tadafil-D Tablet if you have taken MAO inhibitor (a medication for depression) in the last 14 days.

Uses of Tadafil-D Tablet

Treatment of Erectile Dysfunction, and Premature Ejaculation.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Tadafil-D Tablet is a combination drug containing 'impotent agents', primarily used to treat erectile dysfunction (impotence) and premature ejaculation in men. Tadafil-D Tablet contains Tadalafil and  Dapoxetine. Tadalafil works by inhibiting the phosphodiesterase enzyme, which leads to the breakdown of cGMP and causes relaxation of smooth muscles and vasodilation (widening) of blood vessels in the penis. Thereby, it helps to treat erectile dysfunction and symptoms of an enlarged prostate. Dapoxetine works by increasing the serotonin level in nerves, which improves control over ejaculation and increases the time taken to ejaculate.

How Tadafil-D Tablet Works

Tadafil-D Tablet contains Tadalafil and Dapoxetine. Tadalafil works by inhibiting the phosphodiesterase enzyme, which leads to the breakdown of cGMP and causes relaxation of smooth muscles and vasodilation (widening) of blood vessels in the penis. Thereby, it helps to treat erectile dysfunction and symptoms of an enlarged prostate. Dapoxetine works by increasing the serotonin level in nerves, which improves control over ejaculation and hence increases the time taken to ejaculate.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tadafil-D Tablet

  • Nausea
  • Dizziness
  • Vomiting
  • Dryness in mouth
  • Indigestion
  • Nosebleeds
  • Headache
  • Flushing (sense of warmth in the face, ears, neck, and trunk)

What if I have taken an overdose of Tadafil-D Tablet

Do not take more than the prescribed dose of Tadafil-D Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Tadafil-D Tablet if you are allergic to any of its contents; if you are taking nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension), or alpha-blockers; if you have heart problems or stroke, low blood pressure, or uncontrolled high blood pressure, if you ever had a loss of vision. Inform your doctor before taking Tadafil-D Tablet if you have sickle cell anemia (abnormal red blood cells), multiple myeloma (cancer of bone marrow), leukemia (blood cell cancer), deformation in penis, severe kidney or liver problems. Consult your doctor immediately if you experience loss of vision or hearing while taking Tadafil-D Tablet. Tadafil-D Tablet is not intended for use in women. Tadafil-D Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Tadafil-D Tablet should not be given to children as safety and effectiveness have not been established.  Do not take Tadafil-D Tablet if you have taken an MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days.

Drug-Drug Interactions

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TadalafilIsosorbide mononitrate
Critical
TadalafilNitroprusside
Critical

Drug-Drug Interactions

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TadalafilIsosorbide mononitrate
Critical
How does the drug interact with Tadafil-D Tablet 4's:
Coadministration of Tadafil-D Tablet 4's with Isosorbide mononitrate can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Isosorbide mononitrate with Tadafil-D Tablet 4's is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TadalafilNitroprusside
Critical
How does the drug interact with Tadafil-D Tablet 4's:
Taking Tadafil-D Tablet 4's with Nitroprusside can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Tadafil-D Tablet 4's with Nitroprusside is generally avoided as it can lead to an interaction, but it can be taken if prescribed by a doctor. If you experience dizziness, or heart palpitations, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
TadalafilRiociguat
Critical
How does the drug interact with Tadafil-D Tablet 4's:
Taking Tadafil-D Tablet 4's with Riociguat may increase the risk or severity of lower the blood pressure.

How to manage the interaction:
Taking Riociguat with Tadafil-D Tablet 4's is generally not recommended as it can lead to an interaction, but it can be taken together if prescribed by a doctor. However, if you experience dizziness, headache, and nasal congestion consult a doctor. Do not discontinue any medications without consulting a doctor.
TadalafilIsosorbide dinitrate
Critical
How does the drug interact with Tadafil-D Tablet 4's:
Taking Tadafil-D Tablet 4's with Isosorbide dinitrate can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Isosorbide dinitrate with Tadafil-D Tablet 4's is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TadalafilAmyl nitrite
Critical
How does the drug interact with Tadafil-D Tablet 4's:
Taking Tadafil-D Tablet 4's with Amyl Nitrite can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Tadafil-D Tablet 4's with Amyl nitrite is generally avoided as it can lead to interaction. They can be taken only when advised by a doctor. Seek immediate medical attention if you experience symptoms like dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TadalafilSildenafil
Severe
How does the drug interact with Tadafil-D Tablet 4's:
Coadministration of Tadafil-D Tablet 4's and Sildenafil may increase the risk of developing low blood pressure.

How to manage the interaction:
Coadministration of Tadafil-D Tablet 4's and Sildenafil can lead to an interaction, but it can be taken if a doctor advises. However, if you experience dizziness, headache, heart palpitations consult a doctor immediately. Do not stop using any medications without a doctor's advice.
TadalafilKetoconazole
Severe
How does the drug interact with Tadafil-D Tablet 4's:
Coadministration of Ketoconazole with Tadafil-D Tablet 4's may increase the blood levels and effects of Tadafil-D Tablet 4's. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Ketoconazole and Tadafil-D Tablet 4's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if your condition worsens or you experience any symptoms like chest pain or tightness, irregular heartbeat, shortness of breath, consult a doctor. Do not stop using any medications without a doctor's advice.
TadalafilTelithromycin
Severe
How does the drug interact with Tadafil-D Tablet 4's:
Using Tadafil-D Tablet 4's with Telithromycin may significantly increase the blood levels and effects of Tadafil-D Tablet 4's. This can increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Tadafil-D Tablet 4's with Telithromycin can result in an interaction, but it can be taken if a doctor has advised it. Contact a doctor if you experience shortness of breath, visual disturbances, hearing loss, or irregular heartbeat consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
TadalafilMiconazole
Severe
How does the drug interact with Tadafil-D Tablet 4's:
Coadministration of Miconazole with Tadafil-D Tablet 4's may increase blood levels and effects of Tadafil-D Tablet 4's. This can increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between miconazole and Tadafil-D Tablet 4's, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience shortness of breath, dizziness, visual disturbances, or irregular heartbeat. Do not stop using medications without a doctor's advice.
TadalafilCeritinib
Severe
How does the drug interact with Tadafil-D Tablet 4's:
Coadministration of Tadafil-D Tablet 4's with Ceritinib may significantly increase the blood levels and effects of Tadafil-D Tablet 4's.

How to manage the interaction:
Although taking Tadafil-D Tablet 4's with Ceritinib together can cause an interaction, it can be taken if a doctor has suggested it. If you notice trouble breathing, problems with your eyesight, trouble hearing, chest pain, a fast or irregular heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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TADALAFIL-10MG+DAPOXETINE-30MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TADALAFIL-10MG+DAPOXETINE-30MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consuming grapefruit juice with dapoxetine and tadalafil can increase their blood levels and effects. Limit or avoid consuming grapefruit juice while taking dapoxetine and tadalafil.

Diet & Lifestyle Advise

  • Maintaining a healthy weight, eating a balanced diet, and regularly exercising may help you manage erectile dysfunction. 

  • Avoid alcohol consumption to treat your condition effectively, as consuming an excessive amount of alcohol may temporarily impair your ability to get an erection.

  • Avoid usage of tobacco.

  • Share intimate time with your partner.

  • Stay sexually active to prevent further problems with erectile dysfunction.

Habit Forming

No

Therapeutic Class

IMPOTENT AGENTS

Tadafil-D Tablet Substitute

Substitutes safety advice
  • Duraplus Tablet 4'S

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    81.45per tablet
  • Uphold Tablet 4's

    by AYUR

    88.42per tablet
  • TD Pill Tablet 10's

    69.30per tablet
  • Dejac T Tablet 4's

    77.63per tablet
  • Tadox DP Tablet 4's

    by AYUR

    64.13per tablet
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Alcohol

Caution

You are advised not to consume alcohol while taking Tadafil-D Tablet as it may cause increases dizziness.

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Pregnancy

Unsafe

Tadafil-D Tablet contains Tadalafil, which belongs to pregnancy category B. Tadafil-D Tablet is not intended for use in women.

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Breast Feeding

Unsafe

Tadafil-D Tablet is not intended for use in women.

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Driving

Caution

Tadafil-D Tablet may cause dizziness. Therefore you are advised to drive and operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Tadafil-D Tablet if you have liver impairment/liver disease or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor before taking Tadafil-D Tablet if you have kidney impairment/kidney disease or any concerns regarding this.

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Children

Unsafe

Tadafil-D Tablet should not be given to children as safety and effectiveness have not been established.

FAQs

Tadafil-D Tablet is used to treat erectile dysfunction (impotence) and premature ejaculation in men.
Tadafil-D Tablet works by relaxing the blood vessels in the penis, thereby allows the blood flow into the penis when the person is sexually excited.
Yes, the use of Tadafil-D Tablet can cause dry mouth. If you experience dry mouth or feel excessively thirsty, drink plenty of water, and increase fluids intake. You may also keep a lip balm with you if your lips are also dry.
No, do not take Tadafil-D Tablet with nitrates. Taking Tadafil-D Tablet with medicines used to treat angina/chest pain such as nitrates/nitroglycerin may cause severe lowering of blood pressure. You are advised not to take Tadafil-D Tablet if you are taking nitrates or having a history of heart attack/stroke.
No, Tadafil-D Tablet should not be taken along with blood-pressure-lowering medicines. Tadafil-D Tablet relaxes and widens the blood vessels, this causes a decrease in blood pressure. Therefore, if Tadafil-D Tablet is taken and blood pressure lowering medicines, it could lead to a severe blood pressure decrease.
It usually takes 30-60 minutes for Tadafil-D Tablet to show its effect. You should be able to get an erection at any time between 30 minutes to 36 hours after taking Tadafil-D Tablet. However, you need to be sexually excited for Tadafil-D Tablet to work.
No, it is recommended not to take Tadafil-D Tablet along with MAO inhibitor (a medicine for depression) as Tadafil-D Tablet contains Dapoxetine, which is known to contra-indicate if taken along with MAO inhibitor. So, concurrent use of Tadafil-D Tablet and MAO inhibitor should be avoided, and a gap of 14 days should be maintained between the last dose of MAO inhibitor and the first dose Tadafil-D Tablet.
Tadafil-D Tablet may cause side effects like nausea, dizziness, vomiting, dryness in the mouth, indigestion, nosebleeds, headache, and flushing. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Tadafil-D Tablet may cause dizziness. Therefore you are advised to drive and operate machinery only if you are alert.
Store Tadafil-D Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Inform your doctor before taking Tadafil-D Tablet if you have sickle cell anemia (abnormal red blood cells), multiple myeloma (cancer of bone marrow), leukemia (blood cell cancer), deformation in penis, severe kidney or liver problems.

Country of origin

India

Manufacturer/Marketer address

G-1/583,585,586 Sitapura Industrial Area, Riico, Tonk Road, Jaipur (Rajasthan)-302022.
Other Info - TAD0029

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