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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:49 PM IST
Syno-ONE 8mg/ml Injection 6 ml is used in the treatment of knee pain due to osteoarthritis in patients who have failed to respond adequately to simple painkillers or physical therapy and exercise. It contains Sodium hyaluronate, which works by restoring synovial fluid in the knee that helps to lubricate and cushion the joint during movement. Thereby it reduces pain. In some cases, you may experience certain common side effects such as pain, swelling, redness, and warmth at the injection site or fluid in the joint. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Mastro Biologicals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Syno-ONE 8mg/ml Injection 6 ml

Syno-ONE 8mg/ml Injection 6 ml belongs to the class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs)  used in the treatment of knee pain due to osteoarthritis in patients who have failed to respond adequately to simple painkillers or physical therapy and exercise. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness.

Syno-ONE 8mg/ml Injection 6 ml contains Sodium hyaluronate, which works by restoring synovial fluid in the knee that helps to lubricate and cushion the joint during movement. Thereby it reduces pain.

Syno-ONE 8mg/ml Injection 6 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects such as pain, swelling, redness, and warmth at the injection site or fluid in the joint. Most of these side effects do not require medical attention and will resolve gradually over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Sodium hyaluronate or products from birds such as eggs, feathers and poultry, inform your doctor before receiving Syno-ONE 8mg/ml Injection 6 ml. If you are a pregnant or breastfeeding woman, inform your doctor before receiving Syno-ONE 8mg/ml Injection 6 ml. Syno-ONE 8mg/ml Injection 6 ml is not recommended for children as safety and effectiveness have not been established. Syno-ONE 8mg/ml Injection 6 ml should be used with caution in patients with pre-existing chondrocalcinosis (accumulation of calcium salts in hyaline cartilage or fibrocartilage) as it may lead to an acute attack of the condition.

Uses of Syno-ONE 8mg/ml Injection 6 ml

Treatment of Osteoarthritis

Medicinal Benefits

Syno-ONE 8mg/ml Injection 6 ml contains Sodium hyaluronate, a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of knee pain due to osteoarthritis in patients who have failed to respond adequately to simple painkillers or physical therapy and exercise. It works by restoring synovial fluid in the knee that helps to lubricate and cushion the joint during movement. Thereby it reduces pain by decreasing friction in the joints.

Side Effects of Syno-ONE 8mg/ml Injection 6 ml

  • Pain, swelling, redness, and warmth at the injection site
  • Fluid in the joint

Directions for Use

Syno-ONE 8mg/ml Injection 6 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Sodium hyaluronate or products from birds such as eggs, feathers and poultry, inform your doctor before receiving Syno-ONE 8mg/ml Injection 6 ml. If you are a pregnant or breastfeeding woman, inform your doctor before receiving Syno-ONE 8mg/ml Injection 6 ml. Syno-ONE 8mg/ml Injection 6 ml is not recommended for children as safety and effectiveness have not been established. Syno-ONE 8mg/ml Injection 6 ml should be used with caution in patients with pre-existing chondrocalcinosis (accumulation of calcium salts in hyaline cartilage or fibrocartilage) as it may lead to an acute attack of the condition. Avoid activities such as tennis, heavy lifting, jogging, or standing on your feet for a long time immediately after receiving Syno-ONE 8mg/ml Injection 6 ml and for the next 48 hours.

Therapeutic Class

ANALGESICS

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids, such as soy, berries, broccoli, grapes, and green tea, help reduce inflammation.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

How Syno-ONE 8mg/ml Injection 6 ml Works

Syno-ONE 8mg/ml Injection 6 ml contains Sodium hyaluronate, which works by restoring synovial fluid in the knee that helps to lubricate and cushion the joint during movement. Thereby it reduces pain.

What if I have taken an overdose of Syno-ONE 8mg/ml Injection 6 ml

The overdose of Syno-ONE 8mg/ml Injection 6 ml is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms after receiving Syno-ONE 8mg/ml Injection 6 ml, please inform your doctor immediately.
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Alcohol

Consult your doctor

The interaction of Syno-ONE 8mg/ml Injection 6 ml with alcohol is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

The safety and effectiveness of Syno-ONE 8mg/ml Injection 6 ml in pregnant women have not been established. Therefore, if you are pregnant or planning for pregnancy, please inform your doctor before receiving Syno-ONE 8mg/ml Injection 6 ml.

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Breast Feeding

Consult your doctor

The safety and effectiveness of Syno-ONE 8mg/ml Injection 6 ml in breastfeeding women have not been established. Therefore, please inform your doctor if you are breastfeeding before receiving Syno-ONE 8mg/ml Injection 6 ml.

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Driving

Caution

Drive only if you are alert after receiving Syno-ONE 8mg/ml Injection 6 ml.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, please inform your doctor before receiving Syno-ONE 8mg/ml Injection 6 ml.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney disease, please inform your doctor before receiving Syno-ONE 8mg/ml Injection 6 ml.

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Children

Unsafe

Syno-ONE 8mg/ml Injection 6 ml is not recommended for children and adolescents (age 21 years or younger) as the safety and effectiveness of Syno-ONE 8mg/ml Injection 6 ml have not been established in that age group.

Country of origin

India

Manufacturer/Marketer address

Flat No 7, 1st Floor, Dharam Bandhan Chs S V Road, Santa Cruz west, Mumbai - 400 054
Other Info - SYN0347

Author Details

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FAQs

Syno-ONE 8mg/ml Injection 6 ml is used in the treatment of knee pain due to osteoarthritis in patients who have failed to respond adequately to simple painkillers or physical therapy and exercise.
Syno-ONE 8mg/ml Injection 6 ml contains Sodium hyaluronate, a non-steroidal anti-inflammatory drug (NSAID) which works by restoring synovial fluid in the knee that helps to lubricate and cushion the joint during movement. Thereby it reduces knee pain due to osteoarthritis.
You are recommended to avoid activities such as tennis, heavy lifting, jogging, or standing on your feet for a long time immediately after receiving Syno-ONE 8mg/ml Injection 6 ml and for the next 48 hours. Discuss with your doctor regarding the appropriate time to resume these activities.
Syno-ONE 8mg/ml Injection 6 ml should not be used in patients with infections, knee joint infections, or skin disease in the area at the injection site. Also, Syno-ONE 8mg/ml Injection 6 ml should not be administered to patients with known allergies to Sodium hyaluronate.

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Keep Refrigerated. Do not freeze.