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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:49 PM IST
Biotas One Injection is used in the treatment of knee pain due to osteoarthritis in patients who have failed to respond adequately to simple painkillers or physical therapy and exercise. It contains Sodium hyaluronate, which works by restoring synovial fluid in the knee that helps to lubricate and cushion the joint during movement. Thereby it reduces pain. In some cases, you may experience certain common side effects such as pain, swelling, redness, and warmth at the injection site or fluid in the joint. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Biotas One Injection

Biotas One Injection belongs to the class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs)  used in the treatment of knee pain due to osteoarthritis in patients who have failed to respond adequately to simple painkillers or physical therapy and exercise. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness.

Biotas One Injection contains Sodium hyaluronate, which works by restoring synovial fluid in the knee that helps to lubricate and cushion the joint during movement. Thereby it reduces pain.

Biotas One Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects such as pain, swelling, redness, and warmth at the injection site or fluid in the joint. Most of these side effects do not require medical attention and will resolve gradually over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Sodium hyaluronate or products from birds such as eggs, feathers and poultry, inform your doctor before receiving Biotas One Injection. If you are a pregnant or breastfeeding woman, inform your doctor before receiving Biotas One Injection. Biotas One Injection is not recommended for children as safety and effectiveness have not been established. Biotas One Injection should be used with caution in patients with pre-existing chondrocalcinosis (accumulation of calcium salts in hyaline cartilage or fibrocartilage) as it may lead to an acute attack of the condition.

Uses of Biotas One Injection

Treatment of Osteoarthritis

Medicinal Benefits

Biotas One Injection contains Sodium hyaluronate, a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of knee pain due to osteoarthritis in patients who have failed to respond adequately to simple painkillers or physical therapy and exercise. It works by restoring synovial fluid in the knee that helps to lubricate and cushion the joint during movement. Thereby it reduces pain by decreasing friction in the joints.

Side Effects of Biotas One Injection

  • Pain, swelling, redness, and warmth at the injection site
  • Fluid in the joint

Directions for Use

Biotas One Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Sodium hyaluronate or products from birds such as eggs, feathers and poultry, inform your doctor before receiving Biotas One Injection. If you are a pregnant or breastfeeding woman, inform your doctor before receiving Biotas One Injection. Biotas One Injection is not recommended for children as safety and effectiveness have not been established. Biotas One Injection should be used with caution in patients with pre-existing chondrocalcinosis (accumulation of calcium salts in hyaline cartilage or fibrocartilage) as it may lead to an acute attack of the condition. Avoid activities such as tennis, heavy lifting, jogging, or standing on your feet for a long time immediately after receiving Biotas One Injection and for the next 48 hours.

Therapeutic Class

ANALGESICS

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids, such as soy, berries, broccoli, grapes, and green tea, help reduce inflammation.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

How Biotas One Injection Works

Biotas One Injection contains Sodium hyaluronate, which works by restoring synovial fluid in the knee that helps to lubricate and cushion the joint during movement. Thereby it reduces pain.

What if I have taken an overdose of Biotas One Injection

The overdose of Biotas One Injection is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms after receiving Biotas One Injection, please inform your doctor immediately.
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Alcohol

Consult your doctor

The interaction of Biotas One Injection with alcohol is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

The safety and effectiveness of Biotas One Injection in pregnant women have not been established. Therefore, if you are pregnant or planning for pregnancy, please inform your doctor before receiving Biotas One Injection.

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Breast Feeding

Consult your doctor

The safety and effectiveness of Biotas One Injection in breastfeeding women have not been established. Therefore, please inform your doctor if you are breastfeeding before receiving Biotas One Injection.

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Driving

Caution

Drive only if you are alert after receiving Biotas One Injection.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, please inform your doctor before receiving Biotas One Injection.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney disease, please inform your doctor before receiving Biotas One Injection.

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Children

Unsafe

Biotas One Injection is not recommended for children and adolescents (age 21 years or younger) as the safety and effectiveness of Biotas One Injection have not been established in that age group.

Other Info - BI56407

Author Details

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FAQs

Biotas One Injection is used in the treatment of knee pain due to osteoarthritis in patients who have failed to respond adequately to simple painkillers or physical therapy and exercise.
Biotas One Injection contains Sodium hyaluronate, a non-steroidal anti-inflammatory drug (NSAID) which works by restoring synovial fluid in the knee that helps to lubricate and cushion the joint during movement. Thereby it reduces knee pain due to osteoarthritis.
You are recommended to avoid activities such as tennis, heavy lifting, jogging, or standing on your feet for a long time immediately after receiving Biotas One Injection and for the next 48 hours. Discuss with your doctor regarding the appropriate time to resume these activities.
Biotas One Injection should not be used in patients with infections, knee joint infections, or skin disease in the area at the injection site. Also, Biotas One Injection should not be administered to patients with known allergies to Sodium hyaluronate.

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