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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Solian 50 mg Tablet is used to treat schizophrenia and postoperative nausea/vomiting. It contains Amisulpride, which helps restore the balance of certain natural substances in the brain and inhibits certain receptors that induce vomiting. In some cases, this medicine may cause side effects such as dry mouth, constipation, weight gain, decreased blood pressure, and involuntary muscle contractions. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

AMISULPRIDE-50MG

Manufacturer/Marketer :

Sanofi Synthelabo India Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Solian 50 mg Tablet belongs to a group of medicines called 'antipsychotics' primarily used to treat long term (chronic) schizophrenia and postoperative nausea/vomiting. Schizophrenia is characterized by hallucinations symptoms (seeing or hearing things that are not real) and delusions (wrong beliefs). In schizophrenic disorders, there are positive symptoms (like delusions, hallucinations and thought disorders) along with negative symptoms (like blunted effect, emotional and social withdrawal). Nausea is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the stomach's contents through the mouth.

Solian 50 mg Tablet contains Amisulpride, which helps restore the balance of certain natural substances in the brain. The key action of Solian 50 mg Tablet is to block some of the dopamine receptors in the brain and correct dopamine's overactivity. On the other hand, it also affects other brain neurotransmitters such as serotonin (5-HT), which may also lead to its beneficial effects. Solian 50 mg Tablet also stops the sensation of vomiting/nausea by blocking the D2 receptors located in the chemoreceptor trigger zone - CTZ of the brain responsible for inducing vomiting.

Solian 50 mg Tablet can be taken with or without food as prescribed by your doctor. You are advised to take Solian 50 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain side effects such as dryness in the mouth, constipation, weight gain, decreased blood pressure, dystonia (involuntary muscle contractions), akathisia (inability to stay still), parkinsonism, increased prolactin level in blood. Most of these side effects of Solian 50 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist for a longer duration, consult your doctor immediately.

Solian 50 mg Tablet should be avoided if you are allergic to it or any other medicines. Solian 50 mg Tablet is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, inform your doctor before taking Solian 50 mg Tablet . Use Solian 50 mg Tablet with extreme caution in elderly patients above 65 years of age as there is an increased risk of severe adverse effects.  If you have breast cancer, pheochromocytoma (tumor of the adrenal gland), pituitary gland prolactinoma (tumor of the pituitary gland), fits, Parkinson’s disease, kidney or heart problems, inform your doctor before taking Solian 50 mg Tablet . Avoid driving and op taking Solian 50 mg Tablet as it may cause drowsiness or dizziness.

Treatment of Schizophrenia, Postoperative nausea and vomiting (PONV)
Take Solian 50 mg Tablet with or without food as prescribed by your doctor. The doctor determines the dose and duration of the medicine. Swallow the medicines as a whole with a glass of water. Do not crush, chew or break it.

Solian 50 mg Tablet contains Amisulpride, a group of medicines called antipsychotics used to treat a mental illness called schizophrenia and bipolar disorder. Additionally, Solian 50 mg Tablet has anti-emetics properties used either in monotherapy or in combination with other antiemetic drugs to prevent nausea and vomiting, which might occur after surgery. The key action of Solian 50 mg Tablet is to block some of the brain's dopamine receptors and correct dopamine's overactivity, thereby producing a calming effect in the brain. Altogether, Solian 50 mg Tablet may help decrease hallucinations and help you think more clearly and positively about yourself, feel less agitated and take a more active part in everyday life. 

Solian 50 mg Tablet contains Amisulpride, which helps restore the balance of certain natural substances in the brain. The key action of Solian 50 mg Tablet is to block some of the dopamine receptors in the brain and correct dopamine's overactivity. On the other hand, it also affects other brain neurotransmitters such as serotonin (5-HT), which may also lead to its beneficial effects. Solian 50 mg Tablet also stops the sensation of vomiting/nausea by blocking the D2 receptors located in the chemoreceptor trigger zone - CTZ of the brain responsible for inducing vomiting.
Store in a cool and dry place away from sunlight
  • Dizziness

  • Drowsiness 
  • Difficulty sleeping (insomnia) or feeling anxious or agitated
  • Lightheadedness
  • Blurred vision
  • Dry mouth
  • Constipation
  • Weight gain
  • Decreased blood pressure
  • Dystonia (involuntary muscle contractions)
  • Akathisia (inability to stay still)
  • Parkinsonism
  • Breast enlargement in men
  • Unusual production of breast milk in women and men, breast pain
  • High blood sugar (hyperglycaemia)
Take Solian 50 mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include tremors, slow heartbeats, seizures, involuntary muscle movement, and fainting. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
  • Do not take Solian 50 mg Tablet if you are allergic (hypersensitive) to amisulpride or any other ingredients present in this medicine or have a medical history of prolactin-dependent tumor or breast cancer, phaeochromocytoma (a tumor on the adrenal gland), pituitary tumor.

  • Solian 50 mg Tablet should not be given to children as safety has not been established.

  • Use Solian 50 mg Tablet with extreme caution in elderly patients above 65 years of age as there is an increased risk of severe adverse effects.

  • If you are pregnant or breastfeeding, please consult a doctor before taking Solian 50 mg Tablet . Solian 50 mg Tablet may impair fertility, so inform your doctor if you are planning for pregnancy.

  • Inform your doctor if you are previously diagnosed with kidney disease, liver disease epilepsy or seizures (fits), Parkinson's disease, unusual heart rate (rhythm), slow heartbeat (less than 55 beats per minute), low potassium levels in your blood, prolonged QT interval (heart conduction problem), if you or someone else in your family has a history of blood clots, heart problems, stroke, diabetes, have a low number of white blood cells (agranulocytosis), leucopenia (blood disorder).

  • Solian 50 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Solian 50 mg Tablet as it could lead to increased drowsiness and dizziness.  

verifiedApollotooltip
AmisulpridePimozide
Critical
AmisulprideCisapride
Critical

Drug-Drug Interactions

AmisulpridePimozide
Critical
How does the drug interact with Solian 50 mg Tablet 15's:
Taking Pimozide with Solian 50 mg Tablet 15's can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Pimozide with Solian 50 mg Tablet 15's is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideCisapride
Critical
How does the drug interact with Solian 50 mg Tablet 15's:
Taking Solian 50 mg Tablet 15's with Cisapride can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Solian 50 mg Tablet 15's with Cisapride is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideZiprasidone
Critical
How does the drug interact with Solian 50 mg Tablet 15's:
Co-administration of Ziprasidone with Solian 50 mg Tablet 15's can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Solian 50 mg Tablet 15's but can be taken together if prescribed by a doctor. Contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
AmisulprideMetoclopramide
Critical
How does the drug interact with Solian 50 mg Tablet 15's:
Taking Metoclopramide with Solian 50 mg Tablet 15's may increase the risk or severity of side effects.

How to manage the interaction:
Taking Solian 50 mg Tablet 15's with Metoclopramide is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideSaquinavir
Critical
How does the drug interact with Solian 50 mg Tablet 15's:
Taking Saquinavir with Solian 50 mg Tablet 15's can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Solian 50 mg Tablet 15's with Saquinavir is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideGrepafloxacin
Critical
How does the drug interact with Solian 50 mg Tablet 15's:
Taking Solian 50 mg Tablet 15's with Grepafloxacin can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Solian 50 mg Tablet 15's with Grepafloxacin is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
AmisulprideDronedarone
Critical
How does the drug interact with Solian 50 mg Tablet 15's:
Taking Solian 50 mg Tablet 15's with Dronedarone can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Solian 50 mg Tablet 15's with Dronedarone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideMesoridazine
Critical
How does the drug interact with Solian 50 mg Tablet 15's:
Taking Solian 50 mg Tablet 15's with Mesoridazine can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Solian 50 mg Tablet 15's with Mesoridazine is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulpridePromethazine
Severe
How does the drug interact with Solian 50 mg Tablet 15's:
Using Solian 50 mg Tablet 15's together with promethazine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between promethazine and Solian 50 mg Tablet 15's, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not discontinue any medications without consulting a doctor.
AmisulprideMoxifloxacin
Severe
How does the drug interact with Solian 50 mg Tablet 15's:
Taking Solian 50 mg Tablet 15's with Moxifloxacin increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Solian 50 mg Tablet 15's along with moxifloxacin can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Mental illness:

  • Monitor your mood. Keep track of your mood regularly, including factors such as sleep, medicine and activities that can impact your mood. 

  • Exercise daily. Exercise is nice to relieve tension. It can also avoid the weight gain that can be a side effect of your bipolar medication.

  • You may also practice calming techniques such as meditation and deep breathing exercises.

  • Get some normal sleep. Having enough sleep will help to stabilize your mood.

  • Eat a healthy diet. Certain foods may affect your mood more than others. Consider keeping a food log to track what you eat and how certain foods make you feel. Talk to your doctor or nutritionist about foods that may help stabilize your mood.

  • Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.

 

Nausea/Vomiting:

  • Eat smaller meals more often.

  • Drink fluids to stay hydrated. Use oral rehydration solutions (ORS) to replace lost electrolytes.

  • Avoid solid foods until vomiting stops.

  • Avoid foods that might cause stomach upset.

  • Take ample rest. Avoid any activity immediately after eating.

  • Consume plain, light foods such as bread and biscuits.

  • Avoid food with strong flavours and fried food.

  • Ginger tea might help in proper digestion.

No
ANTIPSYCHOTICS

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FAQs

Solian 50 mg Tablet is used to treat long-term (chronic) schizophrenia and postoperative nausea/vomiting. Additionally, Solian 50 mg Tablet is used either in monotherapy or in combination with other antiemetic drugs to prevent nausea and vomiting, which might occur after surgery. The key action of Solian 50 mg Tablet is to block some of the brain's dopamine receptors and correct dopamine's overactivity, thereby producing a calming effect in the brain.
Solian 50 mg Tablet contains Amisulpride, which works by modulating certain chemical messengers (dopamine D2) in the brain, which helps regulate mood, behaviour, nausea and vomiting.
Solian 50 mg Tablet can be used to treat psychotic disorders like schizophrenia, bipolar disorder and depression. However, you should not take this medication without a doctor’s advice.
Solian 50 mg Tablet may affect fertility as it may cause hyperprolactinemia (excessive levels of prolactin hormone in the blood) resulting in amenorrhea (absence of menstrual periods), anovulation (lack of egg release) and impaired fertility.
You are not recommended to stop taking Solian 50 mg Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Solian 50 mg Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Solian 50 mg Tablet , please consult your doctor so that the dose may be gradually reduced.
Solian 50 mg Tablet is not recommended for dementia (loss of memory or other mental abilities) patients especially in elderly people as it may cause severe adverse effects including stroke. Therefore, it is advised to inform your doctor if you have dementia or history of stroke before taking Solian 50 mg Tablet .
Stopping Solian 50 mg Tablet abruptly can cause withdrawal symptoms and stopping it too early could make your illness come back. Please consult your doctor if you want to stop taking Solian 50 mg Tablet .
Take Solian 50 mg Tablet with caution in patients with diabetes as it may increase the risk of having diabetes. It is advised to monitor your blood sugar levels regularly while taking Solian 50 mg Tablet .
Solian 50 mg Tablet is not recommended for children as the safety and effectiveness have not been established.
Solian 50 mg Tablet should be used with caution and only if prescribed by the doctor in elderly patients due to the possible risk of low blood pressure and sedation.
Solian 50 mg Tablet should be used in patients with kidney diseases only when prescribed by a doctor. Dose adjustment and regular monitoring of electrolytes may be required as Solian 50 mg Tablet may alter electrolyte levels in the body.
Solian 50 mg Tablet may cause sleepiness and drowsiness. Do not drive or operate machinery unless you are alert.
Solian 50 mg Tablet should be taken at the same time daily or as prescribed by the doctor.
Solian 50 mg Tablet modulates certain chemical messengers (dopamine D2) in the brain, which helps regulate mood and behaviour.
No, Solian 50 mg Tablet is not indicated for anxiety. It is used to treat schizophrenia and postoperative nausea and vomiting.
Do not take Solian 50 mg Tablet if you are allergic (hypersensitive) to amisulpride or any other ingredients present in this medicine or have a medical history of prolactin-dependent tumour or breast cancer, phaeochromocytoma (a tumour on the adrenal gland), or pituitary tumour.
No, Solian 50 mg Tablet has no habit-forming tendency and is not addictive.
Withdrawal symptoms of Solian 50 mg Tablet are nausea, vomiting, difficulty sleeping, sweating, extreme restlessness, abnormal movements, or muscle stiffness.
Solian 50 mg Tablet may cause side effects like dryness in the mouth, constipation, weight gain, decreased blood pressure, dystonia (involuntary muscle contractions), akathisia (inability to stay still), parkinsonism, and increased prolactin level in blood. Most of these side effects of Solian 50 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist for a longer duration, consult your doctor immediately.
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Other Info - SOL0488

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