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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Sipram-Plus 0.5/10 Tablet is used to treat anxiety disorders. It contains Clonazepam and Escitalopram, which produces a calming effect by suppressing the abnormal activity of nerve cells and increases the serotonin hormone levels that improve mood, behaviour, and cognition in patients with anxiety. It may cause common side effects such as nausea, headache, dizziness, confusion, drowsiness, fatigue, sleeping problems, breathlessness, poor coordination of movements, stomach upset, decreased libido (low sexual desire), and memory problems. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Zuver Pharmaceuticals

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Sipram-Plus 0.5/10 Tablet

Sipram-Plus 0.5/10 Tablet is used to treat anxiety disorders. Anxiety is a mental health disorder characterized by feelings of intense, excessive and persistent worry or fear that are strong enough to interfere with one’s daily activities. Anxiety symptoms include rapid breathing, increased heart rate, restlessness, trouble concentrating, and difficulty falling asleep.

Sipram-Plus 0.5/10 Tablet is a combination of two drugs: clonazepam and escitalopram. Clonazepam produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram increases the serotonin hormone levels that improve mood, behaviour, and cognition in patients with anxiety.

Sipram-Plus 0.5/10 Tablet should be taken as prescribed by the doctor. Common side-effects of Sipram-Plus 0.5/10 Tablet are nausea, headache, dizziness, confusion, drowsiness, fatigue, sleeping problems, breathlessness, poor coordination of movements, stomach upset, decreased libido (low sexual desire), and memory problems. Consult your doctor if any of these side effects persist or worsen.

Do not take Sipram-Plus 0.5/10 Tablet if you are allergic to any of its components. Inform your doctor if you have seizures, liver problems, sleep disorders, lung problems, and alcohol or drug abuse. Do not consume alcohol, as it can increase the risk of side effects. Consult your doctor if you are pregnant or breastfeeding before taking this medicine. Sipram-Plus 0.5/10 Tablet may cause dizziness and drowsiness, so avoid driving vehicles or operating machinery unless you are alert.

Uses of Sipram-Plus 0.5/10 Tablet

Treatment of Anxiety disorder.

Directions for Use

Swallow the tablet as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Sipram-Plus 0.5/10 Tablet is a combination of two medicines: clonazepam and escitalopram. It is used to treat anxiety disorders. Clonazepam increases the effect of gamma-aminobutyric acid (GABA) and produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram is a selective serotonin reuptake inhibitor (SSRI); it increases the serotonin levels in the brain, thereby improving mood and behaviour.

How Sipram-Plus 0.5/10 Tablet Works

Sipram-Plus 0.5/10 Tablet is a combination of two drugs: clonazepam and escitalopram. Clonazepam produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram increases the serotonin hormone levels that improve mood, behaviour, and cognition in patients with anxiety.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sipram-Plus 0.5/10 Tablet

  • Nausea

  • Vomiting

  • Diarrhoea

  • Dizziness

  • Confusion

  • Uncoordinated body movements

  • Drowsiness

  • Fatigue

  • Delayed ejaculation

  • Decreased libido (low sexual desire)

  • Memory problems

What if I have taken an overdose of Sipram-Plus 0.5/10 Tablet

Do not take more than the prescribed dose of Sipram-Plus 0.5/10 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Sipram-Plus 0.5/10 Tablet if you are allergic to any ingredients. Tell your doctor if you are taking antidepressants, antipsychotic medication, antihypertensives, or antibiotics. Talk to your doctor if you have a history of seizures, bipolar disorder, or schizophrenia. Patients with liver diseases, diabetes, heart disease, and bleeding disorders should use the Sipram-Plus 0.5/10 Tablet with caution. Please do not stop taking Sipram-Plus 0.5/10 Tablet abruptly, as it can cause withdrawal symptoms. Sipram-Plus 0.5/10 Tablet may cause suicidal thoughts and worsen anxiety.

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
ClonazepamMorphine
Severe

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
How does the drug interact with Sipram-Plus 0.5/10 Tablet 10's:
Taking Sipram-Plus 0.5/10 Tablet 10's with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Sipram-Plus 0.5/10 Tablet 10's and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamMorphine
Severe
How does the drug interact with Sipram-Plus 0.5/10 Tablet 10's:
Using Morphine together with Sipram-Plus 0.5/10 Tablet 10's can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Morphine with Sipram-Plus 0.5/10 Tablet 10's can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like shortness of breath, feeling tired, having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ClonazepamDezocine
Severe
How does the drug interact with Sipram-Plus 0.5/10 Tablet 10's:
Co-administration of Sipram-Plus 0.5/10 Tablet 10's with Dezocine may increase the risk or severity of respiratory distress.

How to manage the interaction:
Although there is a possible interaction between Sipram-Plus 0.5/10 Tablet 10's and Dezocine, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling tired, dizzy, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
ClonazepamRemifentanil
Severe
How does the drug interact with Sipram-Plus 0.5/10 Tablet 10's:
Co-administration of Remifentanil with Sipram-Plus 0.5/10 Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Sipram-Plus 0.5/10 Tablet 10's with Remifentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
ClonazepamDroperidol
Severe
How does the drug interact with Sipram-Plus 0.5/10 Tablet 10's:
Co-administration of Droperidol with Sipram-Plus 0.5/10 Tablet 10's may increase the severity of slow heart rate and low blood pressure, and using it with Sipram-Plus 0.5/10 Tablet 10's may increase the risks.

How to manage the interaction:
Although taking Sipram-Plus 0.5/10 Tablet 10's and Droperidol together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - heart beating too slowly, low blood pressure, an irregular heartbeat, sudden dizziness, feeling lightheaded, fainting, or your heartbeat feels strange - make sure to call a doctor right away." Do not stop using any medications without a doctor's advice.
ClonazepamTramadol
Severe
How does the drug interact with Sipram-Plus 0.5/10 Tablet 10's:
Co-administration of Sipram-Plus 0.5/10 Tablet 10's with Tramadol may significantly lead to adverse effects such as respiratory difficulties (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Sipram-Plus 0.5/10 Tablet 10's and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamButorphanol
Severe
How does the drug interact with Sipram-Plus 0.5/10 Tablet 10's:
Co-administration of Butorphanol with Sipram-Plus 0.5/10 Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Although taking Sipram-Plus 0.5/10 Tablet 10's and Butorphanol together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamPethidine
Severe
How does the drug interact with Sipram-Plus 0.5/10 Tablet 10's:
Combining Meperidine with Sipram-Plus 0.5/10 Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Pethidine with Sipram-Plus 0.5/10 Tablet 10's together can possibly result in an interaction, but it can be taken if your doctor has advised it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
ClonazepamPentazocine
Severe
How does the drug interact with Sipram-Plus 0.5/10 Tablet 10's:
Co-administration of Pentazocine with Sipram-Plus 0.5/10 Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Sipram-Plus 0.5/10 Tablet 10's with Pentazocine together can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamAlfentanil
Severe
How does the drug interact with Sipram-Plus 0.5/10 Tablet 10's:
Co-administration of Alfentanil with Sipram-Plus 0.5/10 Tablet 10's can increase the risk of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Sipram-Plus 0.5/10 Tablet 10's and Alfentanil, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Attend therapy sessions regularly.

  • Eat a healthy diet.

  • Try to stay active and exercise regularly.

  • Take ample rest. Get enough sleep.

  • Meditate regularly as it helps in easing anxiety.

  • Avoid smoking, caffeine, and alcohol consumption.

  • Foods and drinks like salmon, chamomile, turmeric, dark chocolate, green tea, and yoghurt may help with anxiety.

Habit Forming

Yes

Therapeutic Class

ANXIOLYTICS

Sipram-Plus 0.5/10 Tablet Substitute

Substitutes safety advice
  • Nexito Forte Tablet 10's

    17.91per tablet
  • Stalopam Plus Tablet 15's

    19.74per tablet
  • Depran-10 Tablet 15's

    17.85per tablet
  • Feliz S Plus Tablet 15's

    19.26per tablet
  • Szetalo Plus Tablet 15's

    by AYUR

    22.05per tablet
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Alcohol

Caution

Do not take alcohol as it can increase the risk of side-effects.

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Pregnancy

Unsafe

Sipram-Plus 0.5/10 Tablet may show toxic effects on the fetus. So, it is not recommended for use in women who are pregnant or planning pregnancy. Consult your doctor for further advice.

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Breast Feeding

Caution

Sipram-Plus 0.5/10 Tablet should be used with caution in breastfeeding mothers. Your doctor may advise you to stop breastfeeding while taking this medication.

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Driving

Caution

Do not drive or operate heavy machinery as Sipram-Plus 0.5/10 Tablet may cause drowsiness.

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Liver

Caution

Sipram-Plus 0.5/10 Tablet should be used with caution in patients with severe liver impairment. Dose adjustments may be required in such cases.

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Kidney

Caution

Sipram-Plus 0.5/10 Tablet should be used with caution in patients with kidney failure.

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Children

Caution

Sipram-Plus 0.5/10 Tablet should not be used in children unless prescribed by a child specialist.

FAQs

Sipram-Plus 0.5/10 Tablet is used to treat anxiety disorders.
Sipram-Plus 0.5/10 Tablet decreases the activity in the brain producing a calming effect. It improves mood, behavior and cognition in patients with anxiety.
Long-term use of Sipram-Plus 0.5/10 Tablet may cause suicidal thoughts in some cases. So, use Sipram-Plus 0.5/10 Tablet as prescribed by your doctor. Consult your doctor immediately if you notice any behavioural changes during the use of Sipram-Plus 0.5/10 Tablet .
Sipram-Plus 0.5/10 Tablet can affect mood or behaviour. However, you should not take this medication without a doctor’s advice.
Anxiety is a feeling of fear, worry or uneasiness. Symptoms include irritability, lack of concentration, fatigue, trembling and rapid heartbeat. If you experience repeated episodes of anxiety, consult a doctor immediately.
Sipram-Plus 0.5/10 Tablet may cause a decrease in sexual desire (libido) in men and women. Men can also experience erectile dysfunction. Consult a doctor if you experience any change in sexual desire after taking Sipram-Plus 0.5/10 Tablet .
Sipram-Plus 0.5/10 Tablet may cause drowsiness. So, do not drive or operate heavy machinery while taking Sipram-Plus 0.5/10 Tablet .
Yes, Sipram-Plus 0.5/10 Tablet may cause hair loss ina few people. If you experience excessive hair loss please consult your doctor.
Sipram-Plus 0.5/10 Tablet is a combination medicine used to treat anxiety disorders.
No, do not take a higher than the recommended dose of Sipram-Plus 0.5/10 Tablet as it may cause an overdose. Take Sipram-Plus 0.5/10 Tablet according to the dose and duration prescribed by the doctor to prevent any unpleasant side effects.
Store Sipram-Plus 0.5/10 Tablet at room temperature, protected from light and moisture. Do not freeze. Keep it out of sight and reach of children.
Do not discontinue Sipram-Plus 0.5/10 Tablet without consulting your doctor as it might cause withdrawal symptoms. To treat your condition effectively, keep taking Sipram-Plus 0.5/10 Tablet for the prescribed duration. Talk to the doctor if you experience any difficulty while taking Sipram-Plus 0.5/10 Tablet .

Country of origin

India
Other Info - SIP0020

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