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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Clonotril Plus Tablet is used to treat anxiety disorders. It contains Clonazepam and Escitalopram, which produces a calming effect by suppressing the abnormal activity of nerve cells and increases the serotonin hormone levels that improve mood, behaviour, and cognition in patients with anxiety. It may cause common side effects such as nausea, headache, dizziness, confusion, drowsiness, fatigue, sleeping problems, breathlessness, poor coordination of movements, stomach upset, decreased libido (low sexual desire), and memory problems. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Clonotril Plus Tablet

Clonotril Plus Tablet is used to treat anxiety disorders. Anxiety is a mental health disorder characterized by feelings of intense, excessive and persistent worry or fear that are strong enough to interfere with one’s daily activities. Anxiety symptoms include rapid breathing, increased heart rate, restlessness, trouble concentrating, and difficulty falling asleep.

Clonotril Plus Tablet is a combination of two drugs: clonazepam and escitalopram. Clonazepam produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram increases the serotonin hormone levels that improve mood, behaviour, and cognition in patients with anxiety.

Clonotril Plus Tablet should be taken as prescribed by the doctor. Common side-effects of Clonotril Plus Tablet are nausea, headache, dizziness, confusion, drowsiness, fatigue, sleeping problems, breathlessness, poor coordination of movements, stomach upset, decreased libido (low sexual desire), and memory problems. Consult your doctor if any of these side effects persist or worsen.

Do not take Clonotril Plus Tablet if you are allergic to any of its components. Inform your doctor if you have seizures, liver problems, sleep disorders, lung problems, and alcohol or drug abuse. Do not consume alcohol, as it can increase the risk of side effects. Consult your doctor if you are pregnant or breastfeeding before taking this medicine. Clonotril Plus Tablet may cause dizziness and drowsiness, so avoid driving vehicles or operating machinery unless you are alert.

Uses of Clonotril Plus Tablet

Treatment of Anxiety disorder.

Directions for Use

Swallow the tablet as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Clonotril Plus Tablet is a combination of two medicines: clonazepam and escitalopram. It is used to treat anxiety disorders. Clonazepam increases the effect of gamma-aminobutyric acid (GABA) and produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram is a selective serotonin reuptake inhibitor (SSRI); it increases the serotonin levels in the brain, thereby improving mood and behaviour.

How Clonotril Plus Tablet Works

Clonotril Plus Tablet is a combination of two drugs: clonazepam and escitalopram. Clonazepam produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram increases the serotonin hormone levels that improve mood, behaviour, and cognition in patients with anxiety.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clonotril Plus Tablet

  • Nausea

  • Vomiting

  • Diarrhoea

  • Dizziness

  • Confusion

  • Uncoordinated body movements

  • Drowsiness

  • Fatigue

  • Delayed ejaculation

  • Decreased libido (low sexual desire)

  • Memory problems

What if I have taken an overdose of Clonotril Plus Tablet

Do not take more than the prescribed dose of Clonotril Plus Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Clonotril Plus Tablet if you are allergic to any ingredients. Tell your doctor if you are taking antidepressants, antipsychotic medication, antihypertensives, or antibiotics. Talk to your doctor if you have a history of seizures, bipolar disorder, or schizophrenia. Patients with liver diseases, diabetes, heart disease, and bleeding disorders should use the Clonotril Plus Tablet with caution. Please do not stop taking Clonotril Plus Tablet abruptly, as it can cause withdrawal symptoms. Clonotril Plus Tablet may cause suicidal thoughts and worsen anxiety.

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
ClonazepamTramadol
Severe

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
How does the drug interact with Clonotril Plus Tablet 15's:
Taking Clonotril Plus Tablet 15's with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Clonotril Plus Tablet 15's and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamTramadol
Severe
How does the drug interact with Clonotril Plus Tablet 15's:
Co-administration of Clonotril Plus Tablet 15's with Tramadol may significantly lead to adverse effects such as respiratory difficulties (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Clonotril Plus Tablet 15's and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamCodeine
Severe
How does the drug interact with Clonotril Plus Tablet 15's:
Co-administration of Clonotril Plus Tablet 15's with Codeine may cause serious side effects like respiratory depression.

How to manage the interaction:
Consult a doctor if you are taking Clonotril Plus Tablet 15's with Codeine. Until you know how the medicines affect you, avoid driving or operating hazardous machinery as these medications may cause drowsiness, dizziness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not stop using any medications without talking to a doctor.
ClonazepamEsketamine
Severe
How does the drug interact with Clonotril Plus Tablet 15's:
Co-administration of Clonotril Plus Tablet 15's with Esketamine may increase side effects.

How to manage the interaction:
Although there is a possible interaction, Clonotril Plus Tablet 15's can be taken with Esketamine if prescribed by the doctor. Consult the prescriber if you experience side effects such as confusion, drowsiness, difficulty concentrating, and impairment in judgment, thinking, reaction speed, and motor coordination. Do not discontinue the medication without a doctor's advice.
ClonazepamFentanyl
Severe
How does the drug interact with Clonotril Plus Tablet 15's:
Co-administration of fentanyl and Clonotril Plus Tablet 15's can increase the risk of side effects.

How to manage the interaction:
Although combining Fentanyl and Clonotril Plus Tablet 15's can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you feel sleepiness, loss of balance, or confusion. Do not stop taking any medication without consulting a doctor.
ClonazepamNalbuphine
Severe
How does the drug interact with Clonotril Plus Tablet 15's:
Co-administration of Nalbuphine with Clonotril Plus Tablet 15's can make the side effects worse.

How to manage the interaction:
Although there is a possible interaction between Clonotril Plus Tablet 15's and Nalbuphine, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamRemifentanil
Severe
How does the drug interact with Clonotril Plus Tablet 15's:
Co-administration of Remifentanil with Clonotril Plus Tablet 15's can increase the risk of side effects.

How to manage the interaction:
Taking Clonotril Plus Tablet 15's with Remifentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
ClonazepamMethadone
Severe
How does the drug interact with Clonotril Plus Tablet 15's:
Co-administration of Clonotril Plus Tablet 15's with methadone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Clonotril Plus Tablet 15's with methadone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not discontinue the medication without a doctor's advice.
ClonazepamHydromorphone
Severe
How does the drug interact with Clonotril Plus Tablet 15's:
Co-administration of Clonotril Plus Tablet 15's with Hydromorphone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Clonotril Plus Tablet 15's with Hydromorphone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
ClonazepamPentazocine
Severe
How does the drug interact with Clonotril Plus Tablet 15's:
Co-administration of Pentazocine with Clonotril Plus Tablet 15's can increase the risk of side effects.

How to manage the interaction:
Taking Clonotril Plus Tablet 15's with Pentazocine together can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Attend therapy sessions regularly.

  • Eat a healthy diet.

  • Try to stay active and exercise regularly.

  • Take ample rest. Get enough sleep.

  • Meditate regularly as it helps in easing anxiety.

  • Avoid smoking, caffeine, and alcohol consumption.

  • Foods and drinks like salmon, chamomile, turmeric, dark chocolate, green tea, and yoghurt may help with anxiety.

Habit Forming

Yes

Therapeutic Class

ANXIOLYTICS

Clonotril Plus Tablet Substitute

Substitutes safety advice
  • Nexito Forte Tablet 10's

    17.91per tablet
  • Stalopam Plus Tablet 15's

    19.74per tablet
  • Depran-10 Tablet 15's

    17.85per tablet
  • Feliz S Plus Tablet 15's

    19.26per tablet
  • Szetalo Plus Tablet 15's

    by AYUR

    22.05per tablet
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Alcohol

Caution

Do not take alcohol as it can increase the risk of side-effects.

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Pregnancy

Unsafe

Clonotril Plus Tablet may show toxic effects on the fetus. So, it is not recommended for use in women who are pregnant or planning pregnancy. Consult your doctor for further advice.

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Breast Feeding

Caution

Clonotril Plus Tablet should be used with caution in breastfeeding mothers. Your doctor may advise you to stop breastfeeding while taking this medication.

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Driving

Caution

Do not drive or operate heavy machinery as Clonotril Plus Tablet may cause drowsiness.

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Liver

Caution

Clonotril Plus Tablet should be used with caution in patients with severe liver impairment. Dose adjustments may be required in such cases.

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Kidney

Caution

Clonotril Plus Tablet should be used with caution in patients with kidney failure.

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Children

Caution

Clonotril Plus Tablet should not be used in children unless prescribed by a child specialist.

FAQs

Clonotril Plus Tablet is used to treat anxiety disorders.
Clonotril Plus Tablet decreases the activity in the brain producing a calming effect. It improves mood, behavior and cognition in patients with anxiety.
Long-term use of Clonotril Plus Tablet may cause suicidal thoughts in some cases. So, use Clonotril Plus Tablet as prescribed by your doctor. Consult your doctor immediately if you notice any behavioural changes during the use of Clonotril Plus Tablet .
Clonotril Plus Tablet can affect mood or behaviour. However, you should not take this medication without a doctor’s advice.
Anxiety is a feeling of fear, worry or uneasiness. Symptoms include irritability, lack of concentration, fatigue, trembling and rapid heartbeat. If you experience repeated episodes of anxiety, consult a doctor immediately.
Clonotril Plus Tablet may cause a decrease in sexual desire (libido) in men and women. Men can also experience erectile dysfunction. Consult a doctor if you experience any change in sexual desire after taking Clonotril Plus Tablet .
Clonotril Plus Tablet may cause drowsiness. So, do not drive or operate heavy machinery while taking Clonotril Plus Tablet .
Yes, Clonotril Plus Tablet may cause hair loss ina few people. If you experience excessive hair loss please consult your doctor.
Clonotril Plus Tablet is a combination medicine used to treat anxiety disorders.
No, do not take a higher than the recommended dose of Clonotril Plus Tablet as it may cause an overdose. Take Clonotril Plus Tablet according to the dose and duration prescribed by the doctor to prevent any unpleasant side effects.
Store Clonotril Plus Tablet at room temperature, protected from light and moisture. Do not freeze. Keep it out of sight and reach of children.
Do not discontinue Clonotril Plus Tablet without consulting your doctor as it might cause withdrawal symptoms. To treat your condition effectively, keep taking Clonotril Plus Tablet for the prescribed duration. Talk to the doctor if you experience any difficulty while taking Clonotril Plus Tablet .

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - CLO1339

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