apollo
0
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Simbrinza Opthalmic Suspension 5 ml is used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It works by decreasing the production of aqueous humour; this helps lower the increased pressure in the eye. In some cases, this medicine may cause side effects such as blurred vision, eye redness, discomfort, drowsiness and bad taste in the mouth. Avoid touching the container's tip to the eye, eyelids, or surrounding areas as it may contaminate the product.
Read more
rxMedicinePrescription drug

Whats That

tooltip
Consult Doctor

Manufacturer/Marketer :

Novartis India Ltd

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Simbrinza Opthalmic Suspension 5 ml

Simbrinza Opthalmic Suspension 5 ml is indicated for lowering high intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Glaucoma is an eye disease that causes damage to the optic nerve and results in reduced vision. Ocular hypertension is increased pressure in the eye due to poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow). 
 
Simbrinza Opthalmic Suspension 5 ml is a combination of two drugs: Brinzolamide (carbonic anhydrase inhibitor) and Brimonidine (alpha-2 adrenergic receptor agonist). Simbrinza Opthalmic Suspension 5 ml decreases the production of aqueous humour, thereby helping lower the increased pressure in the eye. 
 
In some cases, you may experience certain common side effects such as blurred vision, eye redness, discomfort, drowsiness and bad taste in the mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult a doctor if you are pregnant or breastfeeding. Simbrinza Opthalmic Suspension 5 ml is not recommended for children below 18 years as the safety and effectiveness have not been established. Simbrinza Opthalmic Suspension 5 ml might cause dizziness, drowsiness, and abnormal/blurred vision, so drive only if you have clear vision. Avoid touching the tip of the dropper as it may contaminate the contents.

Uses of Simbrinza Opthalmic Suspension 5 ml

Treatment of Open-angle glaucoma or ocular hypertension.

Directions for Use

Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.

Medicinal Benefits

Simbrinza Opthalmic Suspension 5 ml is a combination of two drugs: Brinzolamide (carbonic anhydrase inhibitors) and Brimonidine (alpha-2 adrenergic receptor agonists). Simbrinza Opthalmic Suspension 5 ml is indicated for lowering high intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Simbrinza Opthalmic Suspension 5 ml decreases the production of aqueous humour, thereby helping lower the increased pressure in the eye. 

How Simbrinza Opthalmic Suspension 5 ml Works

Simbrinza Opthalmic Suspension 5 ml is a combination of two drugs: Brinzolamide (carbonic anhydrase inhibitor) and Brimonidine (alpha-2 adrenergic receptor agonist). Simbrinza Opthalmic Suspension 5 ml decreases the production of aqueous humour, thereby helping lower the increased pressure in the eye.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Simbrinza Opthalmic Suspension 5 ml

  • Blurred/abnormal vision
  • Eye redness
  • Eye discomfort
  • Drowsiness
  • Bad taste in the mouth 
  • Dry mouth
  • Dizziness
  • Eye surface inflammation
  • Eye pain

What if I have taken an overdose of Simbrinza Opthalmic Suspension 5 ml

Use Simbrinza Opthalmic Suspension 5 ml only as prescribed by the physician. It is advised not to exceed the recommended dose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Simbrinza Opthalmic Suspension 5 ml if you are allergic to any of its components, if you are taking monoamine oxidase inhibitors, antidepressants, if you have severe kidney problems or excess acidity in the blood. Inform your doctor if you have liver problems, narrow-angle glaucoma, dry eyes, cornea problems, coronary heart disease, depression, poor or disturbed blood circulation. Consult a doctor before using Simbrinza Opthalmic Suspension 5 ml if you are pregnant or breastfeeding. Simbrinza Opthalmic Suspension 5 ml is not recommended for children below 18 years as safety and effectiveness have not been established. Simbrinza Opthalmic Suspension 5 ml might cause dizziness, drowsiness, abnormal/blurred vision; so, drive only if you are alert.

Drug-Drug Interactions

verifiedApollotooltip
BrinzolamideSodium salicylate
Severe
BrinzolamideSalsalate
Severe

Drug-Drug Interactions

Login/Sign Up

BrinzolamideSodium salicylate
Severe
How does the drug interact with Simbrinza Opthalmic Suspension 5 ml:
Concomitant use of Simbrinza Opthalmic Suspension 5 ml with sodium salicylate may cause ringing in the ears, nausea, vomiting, headache, dizziness, confusion, hallucinations, rapid breathing, fever, and seizure (convulsions).

How to manage the interaction:
Although there is an interaction, Simbrinza Opthalmic Suspension 5 ml should be used with sodium salicylate only if prescribed by the doctor. However, if you experience ringing in the ears, vomiting, headache, dizziness, or fever, contact your doctor immediately. Do not stop using any medications without consulting your doctor.
BrinzolamideSalsalate
Severe
How does the drug interact with Simbrinza Opthalmic Suspension 5 ml:
Concomitant use of Simbrinza Opthalmic Suspension 5 ml with salsalate can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Simbrinza Opthalmic Suspension 5 ml should be used with salsalate only if prescribed by the doctor. Consult a doctor immediately if you experience ringing in the ears, vomiting, headache, dizziness, and fever. Do not stop using any medications without first talking to your doctor.
BrinzolamideCholine salicylate
Severe
How does the drug interact with Simbrinza Opthalmic Suspension 5 ml:
Taking Simbrinza Opthalmic Suspension 5 ml with Choline salicylate may increase the risk of side effects.

How to manage the interaction:
Although taking Simbrinza Opthalmic Suspension 5 ml and Choline salicylate together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience ringing in your ears, headache, vomiting, dizziness, or palpitations, consult a doctor. Do not stop using any medications without consulting a doctor.
BrinzolamideAspirin
Severe
How does the drug interact with Simbrinza Opthalmic Suspension 5 ml:
Coadministration of Simbrinza Opthalmic Suspension 5 ml with Aspirin may cause side effects.

How to manage the interaction:
Although there is a possible interaction between aspirin and Simbrinza Opthalmic Suspension 5 ml, you can take these medicines together if prescribed by a doctor. However, if you experience ringing in your ears, headache, vomiting, dizziness, or palpitations, please contact a doctor. Do not stop using any medications without talking to a doctor.
BrinzolamideDiflunisal
Severe
How does the drug interact with Simbrinza Opthalmic Suspension 5 ml:
Coadministration of Simbrinza Opthalmic Suspension 5 ml with diflunisal can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Simbrinza Opthalmic Suspension 5 ml should be used with diflunisal only if prescribed by the doctor. Consult a doctor if you experience vomiting, headache, dizziness, or fever. Do not stop using any medications without first talking to your doctor.
BrimonidineBrivaracetam
Moderate
How does the drug interact with Simbrinza Opthalmic Suspension 5 ml:
Simbrinza Opthalmic Suspension 5 ml may be absorbed into the bloodstream and occasionally produce central nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. Concomitant use of brivaracetam with Simbrinza Opthalmic Suspension 5 ml may increase the risk of these side effects.

How to manage the interaction:
Although there is an interaction brivaracetam can be taken with Simbrinza Opthalmic Suspension 5 ml if prescribed by the doctor. Consult the prescriber if you notice dizziness, drowsiness, and difficulty concentrating.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Include fresh fruits and vegetables in your diet.

  • Avoid smoking and alcohol consumption.

  • Avoid intake of baked foods such as cakes, cookies, doughnuts or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damage the optic nerve.

  • Cut down your coffee intake as it may increase pressure in the eye. Replace coffee with green tea.

  • Avoid exercises such as any position where the head is lower than the body, like an inverted yoga pose, as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.

Habit Forming

No

Therapeutic Class

ANTIGLAUCOMA AGENTS

Simbrinza Opthalmic Suspension 5 ml Substitute

Substitutes safety advice
  • Brinzolast Eye Drops 5 ml

    79.20per tablet
  • Sentibrim-BZ Ophthalmic Suspension 5 ml

    75.60per tablet
  • B2 Doc Eye Drop 5 ml

    by AYUR

    86.86per tablet
  • Tregmon Ophthalmic Suspension 5 ml

    78.84per tablet
  • Nubrim-Z Eye Drops 5 ml

    99.80per tablet
bannner image

Alcohol

Caution

Avoid consuming alcohol while using Simbrinza Opthalmic Suspension 5 ml as it might cause increased dizziness and drowsiness. Please consult your doctor if you have any concerns.

bannner image

Pregnancy

Unsafe

Simbrinza Opthalmic Suspension 5 ml belongs to pregnancy category C. Use effective contraception while using Simbrinza Opthalmic Suspension 5 ml. Avoid using Simbrinza Opthalmic Suspension 5 ml during pregnancy unless clearly indicated by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Unsafe

Simbrinza Opthalmic Suspension 5 ml might pass into breastmilk. Avoid breastfeeding while using Simbrinza Opthalmic Suspension 5 ml.

bannner image

Driving

Unsafe

Simbrinza Opthalmic Suspension 5 ml might cause dizziness, drowsiness, and blurred/abnormal vision. So, avoid driving or operating machinery until your vision is clear.

bannner image

Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Simbrinza Opthalmic Suspension 5 ml in patients with liver impairment.

bannner image

Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Simbrinza Opthalmic Suspension 5 ml in patients with kidney impairment. Simbrinza Opthalmic Suspension 5 ml is not recommended for patients with severe kidney disease.

bannner image

Children

Unsafe

Simbrinza Opthalmic Suspension 5 ml is not recommended for children below 18years as the safety and effectiveness have not been established.

FAQs

Simbrinza Opthalmic Suspension 5 ml is used to lower high intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Simbrinza Opthalmic Suspension 5 ml decreases the production of aqueous humour, thereby helps lower the increased pressure in the eye.
Continue using Simbrinza Opthalmic Suspension 5 ml for as long as your doctor has prescribed it to you. Consult the doctor if irritation occurs or worsens.
Simbrinza Opthalmic Suspension 5 ml might cause blurred or abnormal vision. So, avoid driving or operating machinery until your vision is clear to prevent any mishappening.
Do not wear contact lens while using Simbrinza Opthalmic Suspension 5 ml. Remove contact lenses before using Simbrinza Opthalmic Suspension 5 ml and put them back 15minutes after using Simbrinza Opthalmic Suspension 5 ml.
Dry mouth could be a side-effect of Simbrinza Opthalmic Suspension 5 ml. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol; drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Simbrinza Opthalmic Suspension 5 ml can be used with other eye medications if prescribed by the doctor. However, maintain a gap of 5-10minutes between Simbrinza Opthalmic Suspension 5 ml and other eye medications.

Country of origin

INDIA

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India.
Other Info - SIM0163

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button

Add to Cart