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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Brinzolast Eye Drops 5 ml is used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It works by decreasing the production of aqueous humour; this helps lower the increased pressure in the eye. In some cases, this medicine may cause side effects such as blurred vision, eye redness, discomfort, drowsiness and bad taste in the mouth. Avoid touching the container's tip to the eye, eyelids, or surrounding areas as it may contaminate the product.
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Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

OPHTHALMIC

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Brinzolast Eye Drops 5 ml

Brinzolast Eye Drops 5 ml is indicated for lowering high intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Glaucoma is an eye disease that causes damage to the optic nerve and results in reduced vision. Ocular hypertension is increased pressure in the eye due to poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow). 
 
Brinzolast Eye Drops 5 ml is a combination of two drugs: Brinzolamide (carbonic anhydrase inhibitor) and Brimonidine (alpha-2 adrenergic receptor agonist). Brinzolast Eye Drops 5 ml decreases the production of aqueous humour, thereby helping lower the increased pressure in the eye. 
 
In some cases, you may experience certain common side effects such as blurred vision, eye redness, discomfort, drowsiness and bad taste in the mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult a doctor if you are pregnant or breastfeeding. Brinzolast Eye Drops 5 ml is not recommended for children below 18 years as the safety and effectiveness have not been established. Brinzolast Eye Drops 5 ml might cause dizziness, drowsiness, and abnormal/blurred vision, so drive only if you have clear vision. Avoid touching the tip of the dropper as it may contaminate the contents.

Uses of Brinzolast Eye Drops 5 ml

Treatment of Open-angle glaucoma or ocular hypertension.

Directions for Use

Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.

Medicinal Benefits

Brinzolast Eye Drops 5 ml is a combination of two drugs: Brinzolamide (carbonic anhydrase inhibitors) and Brimonidine (alpha-2 adrenergic receptor agonists). Brinzolast Eye Drops 5 ml is indicated for lowering high intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Brinzolast Eye Drops 5 ml decreases the production of aqueous humour, thereby helping lower the increased pressure in the eye. 

How Brinzolast Eye Drops 5 ml Works

Brinzolast Eye Drops 5 ml is a combination of two drugs: Brinzolamide (carbonic anhydrase inhibitor) and Brimonidine (alpha-2 adrenergic receptor agonist). Brinzolast Eye Drops 5 ml decreases the production of aqueous humour, thereby helping lower the increased pressure in the eye.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Brinzolast Eye Drops 5 ml

  • Blurred/abnormal vision
  • Eye redness
  • Eye discomfort
  • Drowsiness
  • Bad taste in the mouth 
  • Dry mouth
  • Dizziness
  • Eye surface inflammation
  • Eye pain

What if I have taken an overdose of Brinzolast Eye Drops 5 ml

Use Brinzolast Eye Drops 5 ml only as prescribed by the physician. It is advised not to exceed the recommended dose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Brinzolast Eye Drops 5 ml if you are allergic to any of its components, if you are taking monoamine oxidase inhibitors, antidepressants, if you have severe kidney problems or excess acidity in the blood. Inform your doctor if you have liver problems, narrow-angle glaucoma, dry eyes, cornea problems, coronary heart disease, depression, poor or disturbed blood circulation. Consult a doctor before using Brinzolast Eye Drops 5 ml if you are pregnant or breastfeeding. Brinzolast Eye Drops 5 ml is not recommended for children below 18 years as safety and effectiveness have not been established. Brinzolast Eye Drops 5 ml might cause dizziness, drowsiness, abnormal/blurred vision; so, drive only if you are alert.

Drug-Drug Interactions

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BrinzolamideSalsalate
Severe
BrinzolamideDiflunisal
Severe

Drug-Drug Interactions

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BrinzolamideSalsalate
Severe
How does the drug interact with Brinzolast Eye Drops 5 ml:
Concomitant use of Brinzolast Eye Drops 5 ml with salsalate can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Brinzolast Eye Drops 5 ml should be used with salsalate only if prescribed by the doctor. Consult a doctor immediately if you experience ringing in the ears, vomiting, headache, dizziness, and fever. Do not stop using any medications without first talking to your doctor.
BrinzolamideDiflunisal
Severe
How does the drug interact with Brinzolast Eye Drops 5 ml:
Coadministration of Brinzolast Eye Drops 5 ml with diflunisal can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Brinzolast Eye Drops 5 ml should be used with diflunisal only if prescribed by the doctor. Consult a doctor if you experience vomiting, headache, dizziness, or fever. Do not stop using any medications without first talking to your doctor.
BrinzolamideCholine salicylate
Severe
How does the drug interact with Brinzolast Eye Drops 5 ml:
Taking Brinzolast Eye Drops 5 ml with Choline salicylate may increase the risk of side effects.

How to manage the interaction:
Although taking Brinzolast Eye Drops 5 ml and Choline salicylate together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience ringing in your ears, headache, vomiting, dizziness, or palpitations, consult a doctor. Do not stop using any medications without consulting a doctor.
BrinzolamideAspirin
Severe
How does the drug interact with Brinzolast Eye Drops 5 ml:
Coadministration of Brinzolast Eye Drops 5 ml with Aspirin may cause side effects.

How to manage the interaction:
Although there is a possible interaction between aspirin and Brinzolast Eye Drops 5 ml, you can take these medicines together if prescribed by a doctor. However, if you experience ringing in your ears, headache, vomiting, dizziness, or palpitations, please contact a doctor. Do not stop using any medications without talking to a doctor.
BrinzolamideSodium salicylate
Severe
How does the drug interact with Brinzolast Eye Drops 5 ml:
Concomitant use of Brinzolast Eye Drops 5 ml with sodium salicylate may cause ringing in the ears, nausea, vomiting, headache, dizziness, confusion, hallucinations, rapid breathing, fever, and seizure (convulsions).

How to manage the interaction:
Although there is an interaction, Brinzolast Eye Drops 5 ml should be used with sodium salicylate only if prescribed by the doctor. However, if you experience ringing in the ears, vomiting, headache, dizziness, or fever, contact your doctor immediately. Do not stop using any medications without consulting your doctor.
BrimonidineBrivaracetam
Moderate
How does the drug interact with Brinzolast Eye Drops 5 ml:
Brinzolast Eye Drops 5 ml may be absorbed into the bloodstream and occasionally produce central nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. Concomitant use of brivaracetam with Brinzolast Eye Drops 5 ml may increase the risk of these side effects.

How to manage the interaction:
Although there is an interaction brivaracetam can be taken with Brinzolast Eye Drops 5 ml if prescribed by the doctor. Consult the prescriber if you notice dizziness, drowsiness, and difficulty concentrating.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include fresh fruits and vegetables in your diet.

  • Avoid smoking and alcohol consumption.

  • Avoid intake of baked foods such as cakes, cookies, doughnuts or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damage the optic nerve.

  • Cut down your coffee intake as it may increase pressure in the eye. Replace coffee with green tea.

  • Avoid exercises such as any position where the head is lower than the body, like an inverted yoga pose, as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.

Habit Forming

No

Therapeutic Class

ANTIGLAUCOMA AGENTS

Brinzolast Eye Drops 5 ml Substitute

Substitutes safety advice
  • Simbrinza Opthalmic Suspension 5 ml

    by AYUR

    127.80per tablet
  • Sentibrim-BZ Ophthalmic Suspension 5 ml

    75.60per tablet
  • B2 Doc Eye Drop 5 ml

    by AYUR

    86.86per tablet
  • Tregmon Ophthalmic Suspension 5 ml

    78.84per tablet
  • Nubrim-Z Eye Drops 5 ml

    99.80per tablet
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Alcohol

Caution

Avoid consuming alcohol while using Brinzolast Eye Drops 5 ml as it might cause increased dizziness and drowsiness. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Brinzolast Eye Drops 5 ml belongs to pregnancy category C. Use effective contraception while using Brinzolast Eye Drops 5 ml. Avoid using Brinzolast Eye Drops 5 ml during pregnancy unless clearly indicated by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Brinzolast Eye Drops 5 ml might pass into breastmilk. Avoid breastfeeding while using Brinzolast Eye Drops 5 ml.

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Driving

Unsafe

Brinzolast Eye Drops 5 ml might cause dizziness, drowsiness, and blurred/abnormal vision. So, avoid driving or operating machinery until your vision is clear.

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Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Brinzolast Eye Drops 5 ml in patients with liver impairment.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Brinzolast Eye Drops 5 ml in patients with kidney impairment. Brinzolast Eye Drops 5 ml is not recommended for patients with severe kidney disease.

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Children

Unsafe

Brinzolast Eye Drops 5 ml is not recommended for children below 18years as the safety and effectiveness have not been established.

FAQs

Brinzolast Eye Drops 5 ml is used to lower high intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Brinzolast Eye Drops 5 ml decreases the production of aqueous humour, thereby helps lower the increased pressure in the eye.
Continue using Brinzolast Eye Drops 5 ml for as long as your doctor has prescribed it to you. Consult the doctor if irritation occurs or worsens.
Brinzolast Eye Drops 5 ml might cause blurred or abnormal vision. So, avoid driving or operating machinery until your vision is clear to prevent any mishappening.
Do not wear contact lens while using Brinzolast Eye Drops 5 ml. Remove contact lenses before using Brinzolast Eye Drops 5 ml and put them back 15minutes after using Brinzolast Eye Drops 5 ml.
Dry mouth could be a side-effect of Brinzolast Eye Drops 5 ml. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol; drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Brinzolast Eye Drops 5 ml can be used with other eye medications if prescribed by the doctor. However, maintain a gap of 5-10minutes between Brinzolast Eye Drops 5 ml and other eye medications.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase Iii, New Delhi - 110020.
Other Info - BRI0640

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