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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Septran Adult Tablet is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). It contains Trimethoprim and Sulfamethoxazole, which stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections. In some cases, you may experience certain common side effects, such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Glaxo India Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Septran Adult Tablet

Septran Adult Tablet is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Septran Adult Tablet does not work against infections caused by the virus, including cold and flu. 

Septran Adult Tablet is a combination of two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Septran Adult Tablet stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Your doctor will decide the dose and duration of Septran Adult Tablet based on your condition and the severity of the infection. In some cases, you may experience certain common side effects, such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Septran Adult Tablet , please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Septran Adult Tablet on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Septran Adult Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption to prevent unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Septran Adult Tablet is not recommended for children below 12 years.

Uses of Septran Adult Tablet

Treatment of Bacterial infections.

Directions for Use

Swallow Septran Adult Tablet as a whole with water; do not crush or chew it.

Medicinal Benefits

Septran Adult Tablet belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Septran Adult Tablet is a combination of two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Septran Adult Tablet kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections. Septran Adult Tablet is a broad-spectrum antibiotic which is active against a wide range of gram-positive and gram-negative bacteria such as Streptococcus pneumonia, Escherichia coli, Klebsiella species, Enterobacter species, Haemophilus influenzae, etc.

How Septran Adult Tablet Works

Septran Adult Tablet is a combination of two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Septran Adult Tablet stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Septran Adult Tablet

  • High levels of potassium in the blood
  • Palpitations (abnormal heartbeats)
  • Thrush or candidiasis (fungal infection)
  • Headache
  • Nausea
  • Diarrhoea
  • Skin rashes

What if I have taken an overdose of Septran Adult Tablet

Do not take more than the prescribed dose of Septran Adult Tablet as it may cause overdose. The symptoms of overdose include headache, dizziness, nausea, vomiting, confusion, loss of appetite, drowsiness, or mental depression. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Septran Adult Tablet if you are allergic to any of its contents; if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (rare blood problem). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Septran Adult Tablet if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight or malnourished; if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Septran Adult Tablet to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
sulfamethoxazoleClozapine
Severe

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
How does the drug interact with Septran Adult Tablet 10's:
Taking Septran Adult Tablet 10's with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between Septran Adult Tablet 10's and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
sulfamethoxazoleClozapine
Severe
How does the drug interact with Septran Adult Tablet 10's:
The combined use of Septran Adult Tablet 10's and clozapine may increase the risk or severity of toxicity.

How to manage the interaction:
There may be a possibility of interaction between Clozapine and Septran Adult Tablet 10's, but it can be taken if prescribed by a doctor. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact your doctor right away. They may be able to recommend other options for you that won't cause any problems. Don't worry, there are solutions available to help you feel better. Do not discontinue any medications without first consulting your doctor.
TrimethoprimLosartan
Severe
How does the drug interact with Septran Adult Tablet 10's:
Coadministration of Losartan with Septran Adult Tablet 10's can increase potassium levels which can lead to severe conditions like kidney problems.

How to manage the interaction:
Taking Losartan with Septran Adult Tablet 10's together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
TrimethoprimQuinapril
Severe
How does the drug interact with Septran Adult Tablet 10's:
Taking Septran Adult Tablet 10's with Quinapril can cause high levels of potassium in the blood.

How to manage the interaction:
Although there is a interaction between Septran Adult Tablet 10's and Quinapril, but it can be taken if prescribed by a doctor. If you notice any of these signs like feeling unwell, feeling dehydrated it's best to contact your doctor right away. Do not stop using any medications without a doctor's advice.
TrimethoprimAzilsartan medoxomil
Severe
How does the drug interact with Septran Adult Tablet 10's:
Coadministration of Azilsartan medoxomil with Septran Adult Tablet 10's may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between azilsartan medoxomil and Septran Adult Tablet 10's, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, or tingling in your hands and feet. Do not discontinue any medications without a doctor's advice.
TrimethoprimTelmisartan
Severe
How does the drug interact with Septran Adult Tablet 10's:
Taking Septran Adult Tablet 10's with telmisartan may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between telmisartan and Septran Adult Tablet 10's, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, and a weak pulse. Do not discontinue the medications without consulting a doctor.
TrimethoprimTetracaine
Severe
How does the drug interact with Septran Adult Tablet 10's:
Co-administration of Septran Adult Tablet 10's with tetracaine can result in blood disorders.

How to manage the interaction:
Although there is an interaction between Septran Adult Tablet 10's and tetracaine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, headache, dizziness, lightheadedness, fatigue, or shortness of breath. Do not discontinue any medications without consulting a doctor.
TrimethoprimProcaine
Severe
How does the drug interact with Septran Adult Tablet 10's:
Co-administration of Septran Adult Tablet 10's with procaine may increase the risk of blood disorders.

How to manage the interaction:
Taking Septran Adult Tablet 10's with Procaine together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like gray skin, feeling sick, headache, dizziness, tiredness, trouble breathing, fast heartbeat, or feeling anxious or confused, contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrimethoprimPhenytoin
Severe
How does the drug interact with Septran Adult Tablet 10's:
Co-administration of Septran Adult Tablet 10's with phenytoin may increase the blood levels and effects of phenytoin.

How to manage the interaction:
Although there is an interaction between Septran Adult Tablet 10's and phenytoin, but can be taken together if prescribed by doctor. However, if you experience nausea, vomiting, twitching eye movements, blurred vision, difficult to speak, loss of balance or coordination, tremors (shaking of hands legs), and confusion contact your doctor immediately. Do not discontinue any medications without consulting to your doctor.
TrimethoprimBupivacaine
Severe
How does the drug interact with Septran Adult Tablet 10's:
Taking Bupivacaine and Septran Adult Tablet 10's may cause methemoglobinemia, (blood disorder that affects how red blood cells deliver oxygen throughout the body).

How to manage the interaction:
Although there is an interaction between bupivacaine and Septran Adult Tablet 10's, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, headache, dizziness, lightheadedness, fatigue, or shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION

Septran Adult Tablet Substitute

Substitutes safety advice
  • Cotrimoxazole 400 mg Tablet 10's

    1.62per tablet
  • Cotrim 5Ml Inj

    by AYUR

    10.62per tablet
  • Klotrim 5Ml Inj

    by AYUR

    36.00per tablet
  • Ivtrim Inj 5Ml

    210.60per tablet
  • Cotrimoxazole SS Tablet 10's

    1.08per tablet
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Alcohol

Unsafe

Avoid alcohol consumption while taking Septran Adult Tablet to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

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Pregnancy

Caution

Please consult your doctor before taking Septran Adult Tablet if you are pregnant. Your doctor will prescribe Septran Adult Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding, your doctor will prescribe Septran Adult Tablet only if the benefits outweigh the risks.

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Driving

Caution

It is unknown whether Septran Adult Tablet affects your ability to drive and operating machinery. Drive only if you are physically stable and mentally focussed.

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Liver

Caution

Please consult your doctor before taking Septran Adult Tablet if you have liver impairment/liver disease. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

Septran Adult Tablet to be taken with caution, especially if you have a history of kidney impairment/kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Septran Adult Tablet is not recommended for children below 12 years.

FAQs

Septran Adult Tablet is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma).
Septran Adult Tablet is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. By inhibiting these, Septran Adult Tablet kills the bacteria and stops their growth. Thereby, helps to treat bacterial infections.
Septran Adult Tablet causes thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.
Diarrhoea might be a side-effect of Septran Adult Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Septran Adult Tablet and consult your doctor. Do not take anti-diarrheal medicine on your own.
It is recommended to complete the course of Septran Adult Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to recurring infections. Continue taking Septran Adult Tablet for as long as your doctor has prescribed to treat your condition effectually.
Do not take Septran Adult Tablet on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.
Septran Adult Tablet may affect certain laboratory test results. Inform the person doing the tests that you are taking Septran Adult Tablet .
Septran Adult Tablet may cause high levels of potassium in the blood, which could lead to abnormal heartbeats (palpitations). Regular monitoring of potassium levels and heart rate is advised while taking Septran Adult Tablet .
You can take Septran Adult Tablet with or without as advised by your doctor. Take Septran Adult Tablet preferably with food to avoid nausea or diarrhoea.
No, Septran Adult Tablet is not an addiction causing medicine. But the dose and duration should be followed as prescribed by your doctor.
Yes, Septran Adult Tablet can be used for urinary tract infection as Septran Adult Tablet is used to prevent infections caused by bacteria.
Pimples are caused due to various reasons. Therefore, please consult your doctor before taking Septran Adult Tablet . If you have any concerns regarding acne, discuss with your doctor.
Yes, Septran Adult Tablet is a stronger antibiotic. It contains two antibiotics namely, Sulfamethoxazole and Trimethoprim.
Septran Adult Tablet can cause side effects such as high levels of potassium in your blood, which can cause abnormal heart beats. Also, it may cause fungal infections like thrush or candidiasis which can affect mouth or vagina and other common side effects like headache, nausea, diarrhoea and skin rashes. If these effects worsen or persist, consult your doctor.
Yes, Septran Adult Tablet is safe to use in most patients. However consult your doctor if you experience any side effects like nausea, vomiting, skin rash, allergic reaction.
Yes, Septran Adult Tablet can cause nausea and vomiting. If these persist or worsen, consult your doctor.
Septran Adult Tablet is contraindicated in patients who have a history of drug-induced immune thrombocytopenia from using trimethoprim and/or sulfonamides, who have a known hypersensitivity to these medications, or who have megaloblastic anemia from a folate deficiencies and in patients with severe renal insufficiency or obvious liver impairment.
Avoid spicy, acidic, and greasy foods while taking Septran Adult Tablet as they may increase your risk of side effects such upset stomach and diarrhoea. Also, Septran Adult Tablet can interact with alcohol. It's best to avoid drinking alcohol while taking Septran Adult Tablet .
Yes, Septran Adult Tablet expires. The expiry date can be found on the packaging.
No, do not stop taking Septran Adult Tablet without first consulting your doctor. Complete the full course of treatment even if you feel better as you may notice an improvement in your symptoms before the infection is cured completely.
If you miss a dose of Septran Adult Tablet , do not worry. Take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for the missed dose.
If you don't feel better after completing the full course of treatment with Septran Adult Tablet , inform your doctor. Also, let your doctor know if your symptoms are worsening while taking Septran Adult Tablet .
Septran Adult Tablet should be used in children above 12 years of age if advised by a doctor.
Avoid taking Septran Adult Tablet if you are allergic to Sulfamethoxazole, Trimethoprim or any other ingredients of Septran Adult Tablet . If you have severe liver or kidney problems, or have ever had thrombocytopenia (blood problem causing bleeding or bruises) or have porphyria (a rare blood problem), inform your doctor before taking Septran Adult Tablet .
Take Septran Adult Tablet as advised by your doctor. It should be taken with food and it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose. Swallow it as whole with a glass of water. Do not crush or chew it.
Store the Septran Adult Tablet in the original package at room temperature. Keep it out of the reach and sight of children.

Country of origin

India

Manufacturer/Marketer address

Dr. Annie Besant Road, Mumbai - 400 030
Other Info - SEP0003

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