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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Ivtrim Inj 5Ml is a combination medicine used in the treatment of bacterial infections of the urinary tract, respiratory tract, ear, lungs, skin, brain and toxoplasmosis. It contains trimethoprim and sulfamethoxazole which stops the production of tetrahydrofolic acid and dihydrofolic acid and thereby stops the growth of the infection-causing bacteria. Sometimes, your may experience common side effects like headache, nausea, diarrhoea, and skin rashes.
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Manufacturer/Marketer :

Converge Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Ivtrim Inj 5Ml

Ivtrim Inj 5Ml belongs to the group of medicines called ‘antibiotics’ used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Ivtrim Inj 5Ml does not work against infections caused by the virus, including cold and flu. 

Ivtrim Inj 5Ml is a combination of two antibiotics, namely: Trimethoprim and Sulfamethoxazole. Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Ivtrim Inj 5Ml stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Ivtrim Inj 5Ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Ivtrim Inj 5Ml, please inform your doctor if you have any allergy (against any antibiotic), severe kidney or liver problems, porphyria (blood disorder), or blood problems which may cause bleeding or bruising. Inform your doctor if you are pregnant or breastfeeding before receiving this injection. Ivtrim Inj 5Ml is not recommended for infants below 6 weeks. Keep your doctor informed about your medical history and your ongoing medications to rule out any side effects/interactions.

Uses of Ivtrim Inj 5Ml

Treatment of Bacterial infections

Directions for Use

Ivtrim Inj 5Ml is administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Ivtrim Inj 5Ml belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Ivtrim Inj 5Ml is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Ivtrim Inj 5Ml kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections. Ivtrim Inj 5Ml is a broad-spectrum antibiotic which is active against a wide range of gram-positive and gram-negative bacteria.

How Ivtrim Inj 5Ml Works

Ivtrim Inj 5Ml is a combination of two antibiotics, namely: Trimethoprim and Sulfamethoxazole. Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Ivtrim Inj 5Ml stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ivtrim Inj 5Ml

  • High levels of potassium in the blood
  • Palpitations (abnormal heartbeats)
  • Thrush or candidiasis (fungal infection)
  • Headache
  • Nausea
  • Diarrhoea
  • Skin rashes

 

What if I have taken an overdose of Ivtrim Inj 5Ml

Ivtrim Inj 5Ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Overdose of Ivtrim Inj 5Ml may cause nausea/vomiting, headache, mental depression, confusion, thrombocytopenia, uremia, and loss of appetite. Your doctor will initiate necessary measures when an overdose is suspected.

Drug Warnings

Do not take Ivtrim Inj 5Ml if you are allergic to any of its contents; if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (a rare blood problem). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Ivtrim Inj 5Ml if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight or malnourished; if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Consult your doctor if you are pregnant or breastfeeding. 

Drug-Drug Interactions

verifiedApollotooltip
TrimethoprimBCG vaccine
Critical
TrimethoprimAmiloride
Severe

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
How does the drug interact with Ivtrim Injection 5 ml:
Taking Ivtrim Injection 5 ml with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between Ivtrim Injection 5 ml and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimAmiloride
Severe
How does the drug interact with Ivtrim Injection 5 ml:
When amiloride is taken with Ivtrim Injection 5 ml it may raise potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm).

How to manage the interaction:
Although there is an interaction between amiloride and Ivtrim Injection 5 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, weakness, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse. Do not discontinue any medications without consulting a doctor.
TrimethoprimAzilsartan medoxomil
Severe
How does the drug interact with Ivtrim Injection 5 ml:
Coadministration of Azilsartan medoxomil with Ivtrim Injection 5 ml may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between azilsartan medoxomil and Ivtrim Injection 5 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, or tingling in your hands and feet. Do not discontinue any medications without a doctor's advice.
TrimethoprimMethotrexate
Severe
How does the drug interact with Ivtrim Injection 5 ml:
Coadministration of Ivtrim Injection 5 ml with methotrexate can increase the risk or severity of blood disorders.

How to manage the interaction:
Although there is a possible interaction between Ivtrim Injection 5 ml and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.
TrimethoprimOlmesartan medoxomil
Severe
How does the drug interact with Ivtrim Injection 5 ml:
Taking olmesartan medoxomil with Ivtrim Injection 5 ml may increase potassium levels in the blood.

How to manage the interaction:
Although taking olmesartan medoxomil with Ivtrim Injection 5 ml may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
TrimethoprimIvacaftor
Severe
How does the drug interact with Ivtrim Injection 5 ml:
When Ivtrim Injection 5 ml is taken with Ivacaftor, the amount of Ivtrim Injection 5 ml in the blood increases.

How to manage the interaction:
Taking Ivtrim Injection 5 ml with Ivacaftor together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting your doctor.
TrimethoprimRamipril
Severe
How does the drug interact with Ivtrim Injection 5 ml:
Taking Ramipril with Ivtrim Injection 5 ml can increase the potassium levels in the blood, increasing the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between ramipril and Ivtrim Injection 5 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop taking any medication without consulting your doctor.
TrimethoprimRopivacaine
Severe
How does the drug interact with Ivtrim Injection 5 ml:
Using ropivacaine with Ivtrim Injection 5 ml can cause higher levels of Ivtrim Injection 5 ml in the blood.

How to manage the interaction:
Although taking Ropivacaine and Ivtrim Injection 5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion contact your doctor immediately. Do not stop using any medications without a doctor's advice.
TrimethoprimPotassium acetate
Severe
How does the drug interact with Ivtrim Injection 5 ml:
Taking potassium acetate with Ivtrim Injection 5 ml may increase potassium levels in the blood which can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Ivtrim Injection 5 ml and Potassium acetate, you can take these medicines together if prescribed by your doctor. However, if you have unusual symptoms contact your doctor right away. Do not discontinue any medications without consulting your doctor.
TrimethoprimBenazepril
Severe
How does the drug interact with Ivtrim Injection 5 ml:
Taking Ivtrim Injection 5 ml with Benazepril can cause high levels of potassium in the blood.

How to manage the interaction:
Although there is an interaction between benazepril and Ivtrim Injection 5 ml, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

 

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION

Ivtrim Inj 5Ml Substitute

Substitutes safety advice
  • Cotrimoxazole 400 mg Tablet 10's

    1.62per tablet
  • Cotrimoxazole SS Tablet 10's

    1.08per tablet
  • Septran Adult Tablet 10's

    0.84per tablet
  • Trisulfose 400mg/80mg Tablet

    0.79per tablet
  • Supristol 400mg/80mg Tablet

    0.80per tablet
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Alcohol

Caution

Avoid alcohol consumption while taking Ivtrim Inj 5Ml to prevent unpleasant side effects.

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Pregnancy

Caution

Please inform your doctor before taking Ivtrim Inj 5Ml if you are pregnant. Ivtrim Inj 5Ml may cause fetal harm. Your doctor will prescribe Ivtrim Inj 5Ml only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Ivtrim Inj 5Ml as it may cause bilirubin displacement and kernicterus (brain damage resulting from high levels of bilirubin in the blood). Please consult your doctor if you have any concerns.

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Driving

Caution

It is unknown whether Ivtrim Inj 5Ml affects your ability to drive and operate machinery. Drive only if you are physically stable and mentally focused.

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Liver

Caution

Please inform your doctor before taking Ivtrim Inj 5Ml if you have liver impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative if necessary based on your condition.

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Kidney

Caution

Please inform your doctor before taking Ivtrim Inj 5Ml if you have kidney impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative if necessary based on your condition.

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Children

Caution

Ivtrim Inj 5Ml is not recommended for infants below 6 weeks.

FAQs

Ivtrim Inj 5Ml belongs to the group of medicines called antibiotics used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma).
Ivtrim Inj 5Ml is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. By inhibiting these, Ivtrim Inj 5Ml kills the bacteria and stops their growth. Thus, it helps to treat bacterial infections.
Ivtrim Inj 5Ml causes thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.
Diarrhoea might be a side-effect of Ivtrim Inj 5Ml. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, inform your doctor. Do not take anti-diarrheal medicine on your own.
Ivtrim Inj 5Ml may affect certain laboratory test results. Inform the lab technician that you are taking Ivtrim Inj 5Ml.
Ivtrim Inj 5Ml may cause high levels of potassium in the blood, which could lead to abnormal heartbeats (palpitations). Regular monitoring of potassium levels and heart rate is advised while taking Ivtrim Inj 5Ml.

Country of origin

INDIA

Manufacturer/Marketer address

7-2-1813,/5/A/1, Vasavi'S Central Court, Unit-Ii , 3Rd Floor, Czech Colony, Sanath Nagar, Hyderabad - 500018., Telangana State, India.
Other Info - IVT0001

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