Rupatch 10 Transdermal Patch belongs to a class of drugs called 'opioid analgesics' primarily used to treat, prevent and treat severe pain. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. Chronic pain lasts for a long duration and is caused due to pathologies like nerve damage and osteoarthritis.

Rupatch 10 Transdermal Patch contains 'Buprenorphine', an opioid partial agonist-antagonist. It works by blocking a chemical messenger in the brain responsible for causing pain. This provides pain relief by acting on specific receptors in the brain.

Use Rupatch 10 Transdermal Patch as advised by your doctor. You may experience certain side effects in some cases, including drowsiness, dry mouth, vomiting, blurred vision, constipation, application site reactions, dizziness or tiredness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Rupatch 10 Transdermal Patch should be avoided if you are allergic to it or any of its ingredients or opioids. Do not use Rupatch 10 Transdermal Patch if you are pregnant or breastfeeding. Rupatch 10 Transdermal Patch is not recommended for children below 18 years of age. Rupatch 10 Transdermal Patch is a habit-forming drug; hence, there is a risk of dependence. Do not stop using this medicine without consulting your doctor, as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors or general unwell feelings. Rupatch 10 Transdermal Patch may decrease fertility in men and women. Do not consume alcohol while using Rupatch 10 Transdermal Patch as it may increase the risk of side effects.

The Rupatch 10 Transdermal Patch contains Buprenorphine. It provides pain relief by acting on specific receptors in the brain and helps in relieving pain. Compared to other opioid analgesics like methadone, Rupatch 10 Transdermal Patch has the advantage of having less sedation (sleepiness), decreased respiratory depression, decreased risk of diversion, fewer withdrawal symptoms and lower risk of toxicity at higher doses.

• Weakness
• Anxiety
• Nervousness
• Dizziness
• Headache
• Constipation
• Diarrhea
• Nausea
• Vomiting
• Sweating
• Application site reactions

Please do not stop using Rupatch 10 Transdermal Patch suddenly, as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to Rupatch 10 Transdermal Patch or any other medicines, please tell your doctor. Do not use Rupatch 10 Transdermal Patch if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Rupatch 10 Transdermal Patch is not recommended for children below 18 years of age. Avoid consuming alcohol with Rupatch 10 Transdermal Patch as it may increase the risk of side effects. Do not use this medicine if you have used an MAO inhibitor (antidepressants) in the past 14 days, as a dangerous drug interaction could occur. Rupatch 10 Transdermal Patch should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Inform your doctor if you have severe breathing problems, asthma, delirium tremens (confusion and shaking after stopping drinking alcohol), hallucinations (seeing and hearing things that are not there), kidney or liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression or other conditions that are treated with antidepressants.

Drug-Drug Interactions: Rupatch 10 Transdermal Patch may have interaction with benzodiazepines (diazepam, temazepam ), pain killers (pentazocine, nalbuphine, codeine, dihydrocodeine, methadone, morphine), anti-depressants (moclobemide, tranylcypromine, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, duloxetine, venlafaxine, amitriptyline, doxepin, trimipramine), antihistamine (promethazine, chlorphenamine), blood thinners (warfarin), anti-anxiety drugs (alprazolam), fits related medicines (carbamazepine), medicines used to prevent nausea (ondansetron), antifungal drugs (ketoconazole), antibiotic (ciprofloxacin, erythromycin), anticancer drugs (ceritinib, lapatinib), immunosuppressants (fingolimod), antipsychotics (droperidol), and HIV/AIDS drugs (saquinavir).

Drug-Food Interactions: Rupatch 10 Transdermal Patch may interact with grapefruit juice. Therefore, avoid grapefruit juice intake with Rupatch 10 Transdermal Patch, as it may increase Rupatch 10 Transdermal Patch levels in the body. Also, avoid St. John's wort (an antidepressant plant) and alcohol consumption while using Rupatch 10 Transdermal Patch, as they may increase the risk of adverse effects such as drowsiness, dizziness, and difficulty concentrating.

Drug-Disease Interactions: People with asthma or any other breathing problems, kidney problems, liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression should consult a doctor before using Rupatch 10 Transdermal Patch.

• ESCITALOPRAM
• CITALOPRAM
• METHADONE
• FLUOXETINE
• DIAZEPAM
• CODEINE
• MORPHINE
• AMITRIPTYLINE
• PROMETHAZINE
• VENLAFAXINE

• Do not go for heavy exercise, as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, biking, and swimming. You can also strengthen your muscles by lifting light weights.
• Drink plenty of water during treatment with Rupatch 10 Transdermal Patch to avoid dry mouth.
• Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while using Rupatch 10 Transdermal Patch.
• Avoid consumption of alcohol and quit smoking.

• Do not use Rupatch 10 Transdermal Patch for a prolonged time, as it may lead to mental or physical dependence on Rupatch 10 Transdermal Patch.
• To avoid getting addicted to this drug, take it in prescribed quantities and as directed by your doctor. Do not self-medicate.
• Rupatch 10 Transdermal Patch causes drowsiness. Avoid activities that require your complete focus and attention, like driving, when you are taking this drug.
• An abrupt stoppage of Rupatch 10 Transdermal Patch can lead to significant withdrawal symptoms. Always discuss decreasing the dosage with your doctor before completely stopping its usage.
• Avoid consuming alcohol while on this medication, as it can lead to dangerous side effects.

Pain: It can be short-term (acute) or long-term (chronic) in nature. Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone, or organs. Chronic pain lasts for a longer duration and is caused by pathologies like nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. Many women have painful periods known as dysmenorrhea, most often menstrual cramps. On the other hand, Osteoarthritis is a degenerative disease that results in chronic pain in joints (especially knee) and stiffness, making daily tasks difficult.