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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Jan 1, 2025 | 2:45 PM IST
Rtsunate SP 200mg/500mg/25mg Tablet belongs to the antimalarial class of medicine used in the treatment of uncomplicated falciparum malaria. This combination medicine works by inhibiting the nucleic acid and protein synthesis of the Plasmodium parasites and thereby stops the spread of the infection. Common side effects include nausea, vomiting, dizziness, abdominal pain, headache, diarrhoea, and fatigue.
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Manufacturer/Marketer :

Themis Medicare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Rtsunate SP 200mg/500mg/25mg Tablet

Rtsunate SP 200mg/500mg/25mg Tablet belongs to a group of anti-malarial drugs used to treat uncomplicated falciparum malaria. Malaria is a mosquito-borne disease caused by the female anopheles mosquito. Malaria is transmitted through the bite of infected mosquitoes, which carry the Plasmodium parasite. The symptoms usually develop within 10 days to 4 weeks after the infection.
 
Rtsunate SP 200mg/500mg/25mg Tablet is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Artesunate generates free radicals, thereby inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during erythrocytic stages. Pyrimethamine binds to haem and forms a complex which is toxic to the malarial parasite. Sulphadoxine prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Rtsunate SP 200mg/500mg/25mg Tablet helps in treating malaria.
 
Take Rtsunate SP 200mg/500mg/25mg Tablet with food. It is advised to take Rtsunate SP 200mg/500mg/25mg Tablet for as long as your doctor has prescribed, depending on your medical condition. In some cases, Rtsunate SP 200mg/500mg/25mg Tablet may cause nausea, vomiting, dizziness, abdominal pain, headache, diarrhoea, and fatigue. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Rtsunate SP 200mg/500mg/25mg Tablet if you are pregnant. Avoid breastfeeding while taking Rtsunate SP 200mg/500mg/25mg Tablet. Rtsunate SP 200mg/500mg/25mg Tablet may cause dizziness, so drive only if you are alert. Rtsunate SP 200mg/500mg/25mg Tablet should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Rtsunate SP 200mg/500mg/25mg Tablet as it could lead to increased dizziness. Keep your doctor informed about the medicines you take and your health condition to rule out any side effects.

Uses of Rtsunate SP 200mg/500mg/25mg Tablet

Treatment of Malaria

Medicinal Benefits

Rtsunate SP 200mg/500mg/25mg Tablet is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Rtsunate SP 200mg/500mg/25mg Tablet belongs to a group of medicines called anti-malarial drugs used to treat uncomplicated Plasmodium falciparum malaria. Artesunate is an anti-parasitic agent that generates free radicals, inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during the erythrocytic stages. Pyrimethamine is an antiparasitic agent that binds to haem and forms a complex toxic to the malarial parasite. Sulphadoxine is an antibiotic that prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Rtsunate SP 200mg/500mg/25mg Tablet helps in treating malaria.

Side Effects of Rtsunate SP 200mg/500mg/25mg Tablet

  • Nausea 
  • Vomiting
  • Dizziness
  • Abdominal pain
  • Diarrhoea
  • Headache
  • Fatigue

Directions for Use

Take Rtsunate SP 200mg/500mg/25mg Tablet with food. Swallow Rtsunate SP 200mg/500mg/25mg Tablet as a whole with a glass of water; do not chew or crush the tablet. Your doctor will decide how long you need to take Rtsunate SP 200mg/500mg/25mg Tablet depending on your medical condition.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Rtsunate SP 200mg/500mg/25mg Tablet if you are allergic to any of its contents. Inform your doctor before taking Rtsunate SP 200mg/500mg/25mg Tablet if you have epilepsy, asthma, blood problems, depression, schizophrenia, bipolar disorder, severe anxiety, glucose-6-phosphate dehydrogenase deficiency, stomach or intestinal infection, heart, kidney, or liver problems. Consult your doctor before taking Rtsunate SP 200mg/500mg/25mg Tablet if you are pregnant. Avoid breastfeeding while taking Rtsunate SP 200mg/500mg/25mg Tablet. Rtsunate SP 200mg/500mg/25mg Tablet may cause dizziness, so drive only if you are alert. Rtsunate SP 200mg/500mg/25mg Tablet should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Rtsunate SP 200mg/500mg/25mg Tablet as it could lead to increased dizziness. Consult your doctor immediately if you notice signs of infection, unusual tiredness, skin rash, unusual bleeding or bruising, red, swollen, or blistered skin.

Therapeutic Class

ANTI- MALARIALS

Drug-Drug Interactions

verifiedApollotooltip
ArtesunateEluxadoline
Severe
ArtesunateCabozantinib
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat nutritious food containing proteins and vitamins.
  • Consume light and digestible foods such as soups, gruel, khichadi, and rice.
  • Drink plenty of fluids. It helps in preventing the formation of kidney stones.
  • Consume fruits rich in vitamin A and C, such as lemon, grapes, beetroot, and carrot.
  • Avoid high-fiber foods, fatty foods, junk foods, and caffeine.
  • Spray insecticides at home and outside to prevent mosquito breeding.
  • Cover your skin in areas that are abundant with mosquitoes. Use insect-repellent creams/spray.
  • Avoid pickles, alcohol, coffee, tea, carbonated beverages, and spicy food.

Habit Forming

No

How Rtsunate SP 200mg/500mg/25mg Tablet Works

Rtsunate SP 200mg/500mg/25mg Tablet is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Artesunate generates free radicals, thereby inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during erythrocytic stages. Pyrimethamine binds to haem and forms a complex which is toxic to the malarial parasite. Sulphadoxine prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Rtsunate SP 200mg/500mg/25mg Tablet helps in treating malaria.

What if I have taken an overdose of Rtsunate SP 200mg/500mg/25mg Tablet

Do not take more than the prescribed dose of Rtsunate SP 200mg/500mg/25mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Caution

Avoid consumption of alcohol while taking Rtsunate SP 200mg/500mg/25mg Tablet as it may lead to increased dizziness.

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Pregnancy

Caution

Consult your doctor before taking Rtsunate SP 200mg/500mg/25mg Tablet if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Rtsunate SP 200mg/500mg/25mg Tablet passes into breastmilk. Avoid breastfeeding while taking Rtsunate SP 200mg/500mg/25mg Tablet.

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Driving

Caution

Rtsunate SP 200mg/500mg/25mg Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Rtsunate SP 200mg/500mg/25mg Tablet should be used with caution in patients with liver problems. Consult your doctor before taking Rtsunate SP 200mg/500mg/25mg Tablet if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Consult your doctor before taking Rtsunate SP 200mg/500mg/25mg Tablet if you have kidney impairment or any concerns regarding this.

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Children

Caution

Rtsunate SP 200mg/500mg/25mg Tablet should be given to children aged 6 months and older only if advised by the doctor.

Country of origin

India
Other Info - RTSU371

Author Details

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FAQs

Rtsunate SP 200mg/500mg/25mg Tablet belongs to a group of anti-malarial drugs used to treat uncomplicated falciparum malaria.
Rtsunate SP 200mg/500mg/25mg Tablet contains Artesunate, Pyrimethamine, and Sulphadoxine. Artesunate generates free radicals, inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during erythrocytic stages. Pyrimethamine binds to haem and forms a complex which is toxic to the malarial parasite. Sulphadoxine prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Rtsunate SP 200mg/500mg/25mg Tablet helps in treating malaria.
Rtsunate SP 200mg/500mg/25mg Tablet might lower the number of platelets in the blood. This could lead to an increased risk of bleeding. Therefore, be cautious while using sharp objects. Inform your doctor if you notice blood in stools, black/tarry stools, or unusual bleeding or bruising.
Rtsunate SP 200mg/500mg/25mg Tablet might lower blood glucose levels. Therefore, consult your doctor before taking Rtsunate SP 200mg/500mg/25mg Tablet if you are diabetic. To prevent any hypoglycaemic events, carry glucose, sugar, honey or candy. Regular monitoring of blood sugar levels whilst taking Rtsunate SP 200mg/500mg/25mg Tablet is advised.
Rtsunate SP 200mg/500mg/25mg Tablet might cause increased sensitivity to the sun. Avoid exposure to sunlight and tanning beds. Wear a protective covering and SPF whilst going outside.
Do not discontinue Rtsunate SP 200mg/500mg/25mg Tablet on your own as it might cause a relapse of the infection. To treat your condition effectually, continue taking Rtsunate SP 200mg/500mg/25mg Tablet for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if your symptoms do not improve or if they become worse.
Anticonvulsant drugs such as Carbamazepine and Phenytoin might lower the anti-malarial activity of Rtsunate SP 200mg/500mg/25mg Tablet. Therefore, consult a doctor before taking Rtsunate SP 200mg/500mg/25mg Tablet along with anticonvulsant drugs.
The common side effects of Rtsunate SP 200mg/500mg/25mg Tablet include nausea, vomiting, dizziness, abdominal pain, headache, diarrhoea, and fatigue. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
If you don't get better after using Rtsunate SP 200mg/500mg/25mg Tablet for the prescribed treatment period, please contact your doctor. They may need to adjust your treatment plan or check for other possible causes of your symptoms. Always follow your doctor's instructions and seek help if your symptoms get worse while using this medicine.
If you miss your dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and take your next dose at the regular time. Never take two doses at once to make up for a missed dose. If you are unsure, consult your doctor for guidance.

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