Larinate-200 Kit

Larinate-200 Kit belongs to a group of anti-malarial drugs used to treat uncomplicated falciparum malaria. Malaria is a mosquito-borne disease caused by the female anopheles mosquito. Malaria is transmitted through the bite of infected mosquitoes, which carry the Plasmodium parasite. The symptoms usually develop within 10 days to 4 weeks after the infection.
 
Larinate-200 Kit is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Artesunate generates free radicals, thereby inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during erythrocytic stages. Pyrimethamine binds to haem and forms a complex which is toxic to the malarial parasite. Sulphadoxine prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Larinate-200 Kit helps in treating malaria.
 
Take Larinate-200 Kit with food. It is advised to take Larinate-200 Kit for as long as your doctor has prescribed, depending on your medical condition. In some cases, Larinate-200 Kit may cause nausea, vomiting, dizziness, abdominal pain, headache, diarrhoea, and fatigue. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Larinate-200 Kit if you are pregnant. Avoid breastfeeding while taking Larinate-200 Kit. Larinate-200 Kit may cause dizziness, so drive only if you are alert. Larinate-200 Kit should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Larinate-200 Kit as it could lead to increased dizziness. Keep your doctor informed about the medicines you take and your health condition to rule out any side effects.

Larinate-200 Kit is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Larinate-200 Kit belongs to a group of medicines called anti-malarial drugs used to treat uncomplicated Plasmodium falciparum malaria. Artesunate is an anti-parasitic agent that generates free radicals, inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during the erythrocytic stages. Pyrimethamine is an antiparasitic agent that binds to haem and forms a complex toxic to the malarial parasite. Sulphadoxine is an antibiotic that prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Larinate-200 Kit helps in treating malaria.

• Nausea 
• Vomiting
• Dizziness
• Abdominal pain
• Diarrhoea
• Headache
• Fatigue

Do not take Larinate-200 Kit if you are allergic to any of its contents. Inform your doctor before taking Larinate-200 Kit if you have epilepsy, asthma, blood problems, depression, schizophrenia, bipolar disorder, severe anxiety, glucose-6-phosphate dehydrogenase deficiency, stomach or intestinal infection, heart, kidney, or liver problems. Consult your doctor before taking Larinate-200 Kit if you are pregnant. Avoid breastfeeding while taking Larinate-200 Kit. Larinate-200 Kit may cause dizziness, so drive only if you are alert. Larinate-200 Kit should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Larinate-200 Kit as it could lead to increased dizziness. Consult your doctor immediately if you notice signs of infection, unusual tiredness, skin rash, unusual bleeding or bruising, red, swollen, or blistered skin.

Drug-Drug Interactions: Larinate-200 Kit may have interaction with anticonvulsant (carbamazepine, phenytoin), antiretroviral (ritonavir, nevirapine), antibiotics (rifampin), anti-malarial (chloroquine), antimetabolite (methotrexate).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Larinate-200 Kit may interact with depression, schizophrenia, bipolar disorder, seizure, colitis, and porphyria.

• CARBAMAZEPINE
• PHENYTOIN
• RITONAVIR
• NEVIRAPINE
• RIFAMPIN
• CHLOROQUINE
• METHOTREXATE

• Eat nutritious food containing proteins and vitamins.
• Consume light and digestible foods such as soups, gruel, khichadi, and rice.
• Drink plenty of fluids. It helps in preventing the formation of kidney stones.
• Consume fruits rich in vitamin A and C, such as lemon, grapes, beetroot, and carrot.
• Avoid high-fiber foods, fatty foods, junk foods, and caffeine.
• Spray insecticides at home and outside to prevent mosquito breeding.
• Cover your skin in areas that are abundant with mosquitoes. Use insect-repellent creams/spray.
• Avoid pickles, alcohol, coffee, tea, carbonated beverages, and spicy food.

• Regular laboratory tests such as blood tests, liver and kidney function tests while taking Larinate-200 Kit are advised.

Malaria: Malaria is a blood disease spread by the female anopheles mosquito. Malaria is spread through the bite of an infected mosquito carrying the Plasmodium parasite. The parasite is released into the bloodstream when an infected mosquito bites a person. The parasite develops in the liver before infecting red blood cells. It then multiplies in red blood cells, resulting in malarial infection. Malaria symptoms include fever, headache, exhaustion, muscle pain, back pain, chills, sweating, nausea, vomiting, and a dry cough. Symptoms typically appear 10 days to 4 weeks after infection.