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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
RPIGAT 20 TABLETS is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. It contains Rivaroxaban, which works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. You may experience bleeding, anemia (low number of red blood cells), and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

RIVAROXABAN-20MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About RPIGAT 20 TABLETS

RPIGAT 20 TABLETS belongs to a class of drugs known as anticoagulants or blood thinner. RPIGAT 20 TABLETS is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.

RPIGAT 20 TABLETS contains Rivaroxaban, a blood thinner that works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Take RPIGAT 20 TABLETS as prescribed. You are advised to take RPIGAT 20 TABLETS for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anemia (low number of red blood cells), and nausea. Most of these side effects of RPIGAT 20 TABLETS do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to RPIGAT 20 TABLETS or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using RPIGAT 20 TABLETS . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking RPIGAT 20 TABLETS . Talk to your doctor immediately if you are pregnant or breastfeeding.

Uses of RPIGAT 20 TABLETS

Prevention of blood clot

Directions for Use

Take RPIGAT 20 TABLETS with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

RPIGAT 20 TABLETS belongs to a class of drugs known as anticoagulants or blood thinner. RPIGAT 20 TABLETS is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. RPIGAT 20 TABLETS works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

How RPIGAT 20 TABLETS Works

RPIGAT 20 TABLETS contains Rivaroxaban, a blood thinner that works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of RPIGAT 20 TABLETS

  • Bleeding

  • Anaemia (low number of red blood cells)

  • Nausea

What if I have taken an overdose of RPIGAT 20 TABLETS

Do not take more than the prescribed dose of RPIGAT 20 TABLETS as it may cause overdose. The symptoms of overdose include bloody/black/tarry stools, unusual bleeding or bruising, blood in urine and coughing up or vomiting blood or material that looks like coffee grounds. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

RPIGAT 20 TABLETS should be used with caution in children. Prolonged use of RPIGAT 20 TABLETS may cause hair loss. Regular blood tests are recommended while taking RPIGAT 20 TABLETS to check the time taken for your blood to clot and the level of platelets (blood cells). If you are known to be allergic to RPIGAT 20 TABLETS or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using RPIGAT 20 TABLETS . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking RPIGAT 20 TABLETS . Talk to your doctor immediately if you are pregnant or breastfeeding.

Drug-Drug Interactions

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RivaroxabanCobicistat
Severe
RivaroxabanApixaban
Severe

Drug-Drug Interactions

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RivaroxabanCobicistat
Severe
How does the drug interact with Rpigat 20 mg Tablet:
Co-administration of Cobicistat and Rpigat 20 mg Tablet can increase the blood levels of Rpigat 20 mg Tablet and increase the risk of bleeding complications.

How to manage the interaction:
Co-administration of Clobicistat and Rpigat 20 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanApixaban
Severe
How does the drug interact with Rpigat 20 mg Tablet:
Coadministration of Rpigat 20 mg Tablet and Apixaban co-administration may raise the risk of unusual bleeding.

How to manage the interaction:
Even though combining Rpigat 20 mg Tablet and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
RivaroxabanVoriconazole
Severe
How does the drug interact with Rpigat 20 mg Tablet:
Co-administration of Voriconazole and Rpigat 20 mg Tablet can increase the blood levels of Rpigat 20 mg Tablet and increase the risk of bleeding.

How to manage the interaction:
Co-administration of Voriconazole and Rpigat 20 mg Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, red or black, tarry stools, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanStreptokinase
Severe
How does the drug interact with Rpigat 20 mg Tablet:
Co-administration of streptokinase and Rpigat 20 mg Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of streptokinase and Rpigat 20 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanTirofiban
Severe
How does the drug interact with Rpigat 20 mg Tablet:
Co-administration of tirofiban and Rpigat 20 mg Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of tirofiban and Rpigat 20 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanItraconazole
Severe
How does the drug interact with Rpigat 20 mg Tablet:
Coadministration of Itraconazole and Rpigat 20 mg Tablet may significantly increase the blood levels of Rpigat 20 mg Tablet. This can increase the risk of serious bleeding complications.

How to manage the interaction:
Itraconazole and Rpigat 20 mg Tablet may interact, but if a doctor prescribes them, you can still use them. If you have dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, a severe headache, weakness, or any of these symptoms, consult a doctor. Never discontinue taking a medication without consulting a doctor.
RivaroxabanKetorolac
Severe
How does the drug interact with Rpigat 20 mg Tablet:
Coadministration of Rpigat 20 mg Tablet together with ketorolac may increase the risk of bleeding problems.

How to manage the interaction:
Although taking Ketorolac and Rpigat 20 mg Tablet together can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
RivaroxabanMeloxicam
Severe
How does the drug interact with Rpigat 20 mg Tablet:
Co-administration of Meloxicam and Rpigat 20 mg Tablet can increase the blood levels of Rpigat 20 mg Tablet and increase the risk of bleeding.

How to manage the interaction:
Co-administration of Meloxicam and Rpigat 20 mg Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanIbuprofen
Severe
How does the drug interact with Rpigat 20 mg Tablet:
Co-administration of Rpigat 20 mg Tablet and Ibuprofen can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of Rpigat 20 mg Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanEnoxaparin
Severe
How does the drug interact with Rpigat 20 mg Tablet:
Co-administration of enoxaparin and Rpigat 20 mg Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of enoxaparin and Rpigat 20 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.

  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with RPIGAT 20 TABLETS and lead to unwanted side effects. Hence try to avoid these juices while taking RPIGAT 20 TABLETS .

  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

RPIGAT 20 TABLETS Substitute

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with RPIGAT 20 TABLETS as it may increase the risk of bleeding.

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Pregnancy

Caution

Tell your doctor before using RPIGAT 20 TABLETS because it may cause harmful effects. So, only use in that condition when a doctor is prescribed.

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Breast Feeding

Caution

RPIGAT 20 TABLETS may pass into breast milk. Therefore consult your doctor.

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Driving

Safe if prescribed

RPIGAT 20 TABLETS usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take RPIGAT 20 TABLETS with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take RPIGAT 20 TABLETS with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

RPIGAT 20 TABLETS is not approved for children. Therefore RPIGAT 20 TABLETS is not safe for children.

FAQs

RPIGAT 20 TABLETS is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation.
No, you are not recommended to stop taking RPIGAT 20 TABLETS without consulting your doctor to worsen the condition. Therefore, take RPIGAT 20 TABLETS for as long as your doctor has prescribed it.
No, RPIGAT 20 TABLETS is not expected to cause weight gain. If you notice unexpected weight gain and think it is because of this RPIGAT 20 TABLETS , immediately consult your doctor and inform him about it.
RPIGAT 20 TABLETS has many beneficial effects, but it has the ability to make you bleed more than normal. Even with minor injuries as it decreases your ability to blood clotting. Sometimes RPIGAT 20 TABLETS may cause severe bleeding that may be dangerous and may require urgent medical care. This risk may be increased in people taking RPIGAT 20 TABLETS along with other blood thinner medicines.
Avoid taking grapefruit and grapefruit juice while taking RPIGAT 20 TABLETS , and it contains compounds that slow down the metabolism of RPIGAT 20 TABLETS and increase the activity leading to bleeding.
It is not known that RPIGAT 20 TABLETS causes hair loss. Kindly contact your doctor.
RPIGAT 20 TABLETS is a type of medicine known as an anticoagulant. RPIGAT 20 TABLETS works by stopping a clotting factor called factor Xa from working. This thins your blood, so it takes longer to clot.
You should take RPIGAT 20 TABLETS just after a meal or snack, or as advised by the doctor. It is important to take it with food to help your body absorb the entire dose.
The side effects of RPIGAT 20 TABLETS include bleeding, nausea and anemia (lack of blood). If these side effects persist or worsen, please consult your doctor.
Yes, RPIGAT 20 TABLETS is a blood thinner. It prevents the blood from clotting inside the blood vessels and also prevents the blood clots from recurring in the blood vessels.
Avoid taking grapefruit and grapefruit juice while taking RPIGAT 20 TABLETS as grapefruit contains compounds that slow down the RPIGAT 20 TABLETS metabolism and increase the activity leading to bleeding. However, if you are taking some other blood thinner like warfarin, you should avoid taking any food that increases the vitamin K activity or increases the blood clotting such as brussels, spinach, sprouts, broccoli, mustard greens, asparagus and green tea. But, the use of these food items is not restricted with RPIGAT 20 TABLETS .

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - RPI0003

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