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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Axcelto-20 Tablet is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. It contains Rivaroxaban, which works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. You may experience bleeding, anemia (low number of red blood cells), and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Whats That

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Composition :

RIVAROXABAN-20MG

Manufacturer/Marketer :

Akcent Healthcare India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Axcelto-20 Tablet

Axcelto-20 Tablet belongs to a class of drugs known as anticoagulants or blood thinner. Axcelto-20 Tablet is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.

Axcelto-20 Tablet contains Rivaroxaban, a blood thinner that works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Take Axcelto-20 Tablet as prescribed. You are advised to take Axcelto-20 Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anemia (low number of red blood cells), and nausea. Most of these side effects of Axcelto-20 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Axcelto-20 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Axcelto-20 Tablet . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Axcelto-20 Tablet . Talk to your doctor immediately if you are pregnant or breastfeeding.

Uses of Axcelto-20 Tablet

Prevention of blood clot

Directions for Use

Take Axcelto-20 Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Axcelto-20 Tablet belongs to a class of drugs known as anticoagulants or blood thinner. Axcelto-20 Tablet is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. Axcelto-20 Tablet works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

How Axcelto-20 Tablet Works

Axcelto-20 Tablet contains Rivaroxaban, a blood thinner that works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Axcelto-20 Tablet

  • Bleeding

  • Anaemia (low number of red blood cells)

  • Nausea

What if I have taken an overdose of Axcelto-20 Tablet

Do not take more than the prescribed dose of Axcelto-20 Tablet as it may cause overdose. The symptoms of overdose include bloody/black/tarry stools, unusual bleeding or bruising, blood in urine and coughing up or vomiting blood or material that looks like coffee grounds. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Axcelto-20 Tablet should be used with caution in children. Prolonged use of Axcelto-20 Tablet may cause hair loss. Regular blood tests are recommended while taking Axcelto-20 Tablet to check the time taken for your blood to clot and the level of platelets (blood cells). If you are known to be allergic to Axcelto-20 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Axcelto-20 Tablet . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Axcelto-20 Tablet . Talk to your doctor immediately if you are pregnant or breastfeeding.

Drug-Drug Interactions

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RivaroxabanAbciximab
Severe
RivaroxabanTirofiban
Severe

Drug-Drug Interactions

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RivaroxabanAbciximab
Severe
How does the drug interact with Axcelto-20 Tablet:
Co-administration of Abciximab and Axcelto-20 Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Abciximab and Axcelto-20 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanTirofiban
Severe
How does the drug interact with Axcelto-20 Tablet:
Co-administration of tirofiban and Axcelto-20 Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of tirofiban and Axcelto-20 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanUrokinase
Severe
How does the drug interact with Axcelto-20 Tablet:
Co-administration of urokinase and Axcelto-20 Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of urokinase and Axcelto-20 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanFosphenytoin
Severe
How does the drug interact with Axcelto-20 Tablet:
Co-administration of Fosphenytoin and Axcelto-20 Tablet can reduce the blood levels of Axcelto-20 Tablet and increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of Fosphenytoin and Axcelto-20 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
RivaroxabanPrimidone
Severe
How does the drug interact with Axcelto-20 Tablet:
Co-administration of primidone and Axcelto-20 Tablet may reduce the blood levels of Axcelto-20 Tablet, which may increase the risk or severity of bleeding problems.

How to manage the interaction:
Although there is an interaction between primidone and Axcelto-20 Tablet, it can be taken if advised by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RivaroxabanMefenamic acid
Severe
How does the drug interact with Axcelto-20 Tablet:
Coadministration of Mefenamic acid with Axcelto-20 Tablet can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Mefenamic acid with Axcelto-20 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
RivaroxabanNaproxen
Severe
How does the drug interact with Axcelto-20 Tablet:
Coadministration of Naproxen and Axcelto-20 Tablet may increase the risk or severity of bleeding problems.

How to manage the interaction:
There may be a possible interaction between Naproxen and Axcelto-20 Tablet, but they can be taken together if they are prescribed by doctor. However, if you experience unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness, consult the doctor. Do not discontinue any medication without a doctor's advice.
RivaroxabanClopidogrel
Severe
How does the drug interact with Axcelto-20 Tablet:
Coadministration of Clopidogrel with Axcelto-20 Tablet increases the risk of severe bleeding due to the additive effect.

How to manage the interaction:
Although taking clopidogrel with Axcelto-20 Tablet may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, coughing up or vomiting blood that looks like coffee grounds, or having a severe headache consult your doctor immediately. Do not discontinue any medication without consulting your doctor.
RivaroxabanRifampicin
Severe
How does the drug interact with Axcelto-20 Tablet:
Taking Axcelto-20 Tablet with rifampicin can decrease the blood levels of Axcelto-20 Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Axcelto-20 Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RivaroxabanEnoxaparin
Severe
How does the drug interact with Axcelto-20 Tablet:
Co-administration of enoxaparin and Axcelto-20 Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of enoxaparin and Axcelto-20 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.

  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Axcelto-20 Tablet and lead to unwanted side effects. Hence try to avoid these juices while taking Axcelto-20 Tablet .

  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Axcelto-20 Tablet Substitute

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Axcelto-20 Tablet as it may increase the risk of bleeding.

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Pregnancy

Caution

Tell your doctor before using Axcelto-20 Tablet because it may cause harmful effects. So, only use in that condition when a doctor is prescribed.

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Breast Feeding

Caution

Axcelto-20 Tablet may pass into breast milk. Therefore consult your doctor.

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Driving

Safe if prescribed

Axcelto-20 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Axcelto-20 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Axcelto-20 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Axcelto-20 Tablet is not approved for children. Therefore Axcelto-20 Tablet is not safe for children.

FAQs

Axcelto-20 Tablet is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation.
No, you are not recommended to stop taking Axcelto-20 Tablet without consulting your doctor to worsen the condition. Therefore, take Axcelto-20 Tablet for as long as your doctor has prescribed it.
No, Axcelto-20 Tablet is not expected to cause weight gain. If you notice unexpected weight gain and think it is because of this Axcelto-20 Tablet , immediately consult your doctor and inform him about it.
Axcelto-20 Tablet has many beneficial effects, but it has the ability to make you bleed more than normal. Even with minor injuries as it decreases your ability to blood clotting. Sometimes Axcelto-20 Tablet may cause severe bleeding that may be dangerous and may require urgent medical care. This risk may be increased in people taking Axcelto-20 Tablet along with other blood thinner medicines.
Avoid taking grapefruit and grapefruit juice while taking Axcelto-20 Tablet , and it contains compounds that slow down the metabolism of Axcelto-20 Tablet and increase the activity leading to bleeding.
It is not known that Axcelto-20 Tablet causes hair loss. Kindly contact your doctor.
Axcelto-20 Tablet is a type of medicine known as an anticoagulant. Axcelto-20 Tablet works by stopping a clotting factor called factor Xa from working. This thins your blood, so it takes longer to clot.
You should take Axcelto-20 Tablet just after a meal or snack, or as advised by the doctor. It is important to take it with food to help your body absorb the entire dose.
The side effects of Axcelto-20 Tablet include bleeding, nausea and anemia (lack of blood). If these side effects persist or worsen, please consult your doctor.
Yes, Axcelto-20 Tablet is a blood thinner. It prevents the blood from clotting inside the blood vessels and also prevents the blood clots from recurring in the blood vessels.
Avoid taking grapefruit and grapefruit juice while taking Axcelto-20 Tablet as grapefruit contains compounds that slow down the Axcelto-20 Tablet metabolism and increase the activity leading to bleeding. However, if you are taking some other blood thinner like warfarin, you should avoid taking any food that increases the vitamin K activity or increases the blood clotting such as brussels, spinach, sprouts, broccoli, mustard greens, asparagus and green tea. But, the use of these food items is not restricted with Axcelto-20 Tablet .

Country of origin

India

Manufacturer/Marketer address

C B :- 385 A, Second Floor, Naria, Delhi - 110082, Near By Ring Road
Other Info - AXC0032

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