Rufenyl 50 mcg Injection 2 ml belongs to a class of drugs known as 'opioid analgesics,' primarily used to relieve pain. It is used to reduce pain before and after surgery. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. Chronic pain lasts for a long duration and is caused due to pathologies like nerve damage and osteoarthritis.

Rufenyl 50 mcg Injection 2 ml contains Fentanyl, which is primarily used to treat pain. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

Rufenyl 50 mcg Injection 2 ml will be administered to your vein by a trained healthcare professional; hence, do not self-administer. This medicine may cause certain common side effects such as dizziness, sleepiness, increased or decreased blood pressure, and irregular heartbeat in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Avoid receiving Rufenyl 50 mcg Injection 2 ml if you are allergic to it or opioids or any ingredients of Rufenyl 50 mcg Injection 2 ml.  Inform your doctor if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease before starting treatment with Rufenyl 50 mcg Injection 2 ml. Avoid consuming alcohol along with Rufenyl 50 mcg Injection 2 ml as it could lead to increased dizziness. Rufenyl 50 mcg Injection 2 ml should not be used for a prolonged time, as it may lead to mental or physical dependence on Rufenyl 50 mcg Injection 2 ml. Using MAO inhibitor medicine along with Rufenyl 50 mcg Injection 2 ml may lead to serious side effects. Hence inform your doctor if you are using any such medicine. Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with Rufenyl 50 mcg Injection 2 ml, especially in people affected with high blood pressure and a history of heart failure. Rufenyl 50 mcg Injection 2 ml is not recommended for children below 18 years of age.

Rufenyl 50 mcg Injection 2 ml belongs to a class of drugs known as 'opioid analgesics,' containing Fentanyl, primarily used to relieve pain. It is used to treat breakthrough pain (sudden episodes of pain occurring despite treatment with pain medication) in cancer patients. It is also used as an anaesthetic agent for short operations and relieves pain in conditions like rheumatoid arthritis and osteoarthritis and pain affecting the joints and muscles. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

• Nausea and Vomiting
• Muscle stiffness (which may involve your chest muscles)
• Agitation
• Drowsiness
• Dizziness
• Problems with vision
• Difficulty in breathing or wheezing
• Irregular heartbeat (slow or fast)
• Pain in your veins
• Difficulty with body movements
• Confusion 
• Injection site reactions

Do not receive Rufenyl 50 mcg Injection 2 ml if you are allergic to opioids or any ingredients of Rufenyl 50 mcg Injection 2 ml.Inform your doctor if you have respiratory disorders, heart diseases, high blood pressure, liver/kidney disease or hypothyroidism (underactive thyroid) before starting treatment with Rufenyl 50 mcg Injection 2 ml. Do not take Rufenyl 50 mcg Injection 2 ml for a prolonged time, Rufenyl 50 mcg Injection 2 ml contains fentanyl that may lead to mental or physical dependence on Rufenyl 50 mcg Injection 2 ml. Do not take Rufenyl 50 mcg Injection 2 ml if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Rufenyl 50 mcg Injection 2 ml is not recommended for children below 18 years of age. Using MAO inhibitor medicine along with Rufenyl 50 mcg Injection 2 ml may lead to serious side effects. Hence inform your doctor if you are using any such medicine. Rufenyl 50 mcg Injection 2 ml should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Avoid consuming alcohol while on this medication, as it can lead to excessive sleepiness. Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with Rufenyl 50 mcg Injection 2 ml, especially in people affected with high blood pressure and a history of heart failure.

• Drug-Drug Interaction: Rufenyl 50 mcg Injection 2 ml is known to interact with antihistamines (cetirizine, phenylephrine), anti-HIV medicines (ritonavir, indinavir, saquinavir), anti-anxiety medicines (droperidol),  anti-fungal medicines (fluconazole, voriconazole), anti-depressants (citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, venlafaxine), MAO Inhibitors (Isocarboxazid, Selegiline).

• Drug-Food Interaction: Rufenyl 50 mcg Injection 2 ml is known to interact with alcohol and grapefruit juice.

• Drug-Disease Interaction: Rufenyl 50 mcg Injection 2 ml is known to interact in patients who have or had an underactive thyroid gland, lung disease, myasthenia gravis (a muscle disorder), liver or kidney disease, alcoholism, severe undiagnosed headaches, or recently suffered a head injury, low blood volume, pain in the right upper side of your abdomen (bile duct).

• CETIRIZINE
• PHENYLEPHRINE
• RITONAVIR
• INDINAVIR
• SAQUINAVIR
• DROPERIDOL
• FLUCONAZOLE
• VORICONAZOLE
• CITALOPRAM
• DULOXETINE
• ESCITALOPRAM
• FLUOXETINE
• FLUVOXAMINE
• PAROXETINE
• SERTRALINE
• VENLAFAXINE

• Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
• In the chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that have a minimum level of chemicals called cytokines, which ramp up inflammation.
• Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible, and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis.  Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.
• Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating many simple carbohydrates in processed foods.

• Regular monitoring of blood pressure and heart rate is required while on treatment with Rufenyl 50 mcg Injection 2 ml.
• Rufenyl 50 mcg Injection 2 ml causes drowsiness. Avoid doing activities that require your complete focus and attention, like driving when on this drug.
• An abrupt stoppage of Rufenyl 50 mcg Injection 2 ml can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
• Avoid consuming alcohol while on this medication, as it can lead to dangerous side effects.
• Rufenyl 50 mcg Injection 2 ml is unsafe for usage if you're pregnant or are planning to get pregnant. Discuss with your doctor in such situations about changing/replacing the medicine with safer alternatives.
• To avoid getting addicted to this drug, take it in prescribed quantities and as directed by your doctor. Do not self-medicate.

• Rufenyl 50 mcg Injection 2 ml should not be administered during labour as it may affect the baby’s breathing.

Pain: Pain is an unpleasant emotion brought on by an illness or injury. Acute (short-term) or chronic pain both exist (long-term). It may be widespread (body-wide aches) or localised (pain in a specific body area). Since different people have varying pain tolerance levels, pain is highly subjective. Even though pain is uncomfortable and inconvenient, it can provide clues as to what is wrong with the body. Cramps, headaches, bone fractures, stomach pain, arthritis (swelling of one or more joints), muscle strain or overuse, cuts, the flu, fibromyalgia, and irritable bowel syndrome are a few conditions that can cause pain (muscle pain with stiffness and tenderness).