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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Durogesic 50 mcg Patches is used to treat pain. It contains Fentanyl, which works by blocking a chemical messenger in the brain responsible for causing pain. Hence, it changes how the brain and nervous system respond to pain. Common side effects of Durogesic 50 mcg Patches are dizziness, sleepiness, increased or decreased blood pressure, application site reactions, and irregular heartbeat.
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Composition :

FENTANYL-50MCG

Manufacturer/Marketer :

Janssen Pharmaceuticals Pvt Ltd

Consume Type :

TOPICAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Durogesic 50 mcg Patches

Durogesic 50 mcg Patches belongs to a class of drugs known as 'opioid analgesics,' primarily used to relieve pain. It is used to treat severe pain. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. Chronic pain lasts for a long duration and is caused due to pathologies like nerve damage and osteoarthritis.

Durogesic 50 mcg Patches contains Fentanyl, which is primarily used to treat pain. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

Durogesic 50 mcg Patches is an external preparation. It is mostly given by your doctor in the hospital setting. Durogesic 50 mcg Patches may cause certain side effects such as dizziness, sleepiness, increased or decreased blood pressure, application site reactions, and irregular heartbeat in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Durogesic 50 mcg Patches should be avoided if you are allergic to it or any ingredients of it or opioids. Inform your doctor before using Durogesic 50 mcg Patches if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease. Avoid consuming alcohol along with Durogesic 50 mcg Patches as it could lead to increased dizziness. Do not use Durogesic 50 mcg Patches for a prolonged time as it may lead to mental or physical dependence on Durogesic 50 mcg Patches. This medicine is not recommended for children below 18 years of age. Do not use this medicine if you have used an MAO inhibitor in the past 14 days, as this combination may cause serious interaction. Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with Durogesic 50 mcg Patches, especially in people affected with high blood pressure and a history of heart failure. Durogesic 50 mcg Patches is not recommended for mild pain or pain that lasts for a very short time.

Uses of Durogesic 50 mcg Patches

Treatment of Pain

Directions for Use

Transdermal patch: It will be applied by a healthcare professional in a hospital setting.

Medicinal Benefits

Durogesic 50 mcg Patches belongs to a class of drugs known as 'opioid analgesics,' containing Fentanyl, primarily used to relieve pain. It is used to treat severe pain. It is also used as an anaesthetic agent for short operations and relieves pain in conditions like dental surgery or tonsil surgery. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

How Durogesic 50 mcg Patches Works

Durogesic 50 mcg Patches contains Fentanyl, which is primarily used to treat pain. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Durogesic 50 mcg Patches

  • Nausea and vomiting
  • Muscle stiffness (which may involve your chest muscles)
  • Agitation
  • Drowsiness
  • Dizziness
  • Problems with vision
  • Pain in your veins
  • Difficulty with body movements
  • Skin rash
  • Confusion after the operation

What if I have taken an overdose of Durogesic 50 mcg Patches

Do not apply Durogesic 50 mcg Patches in large amounts or use it for a long time than recommended, as it does not give quick or better results but increases the risk of side effects. Accidental oral ingestion could be harmful, seek immediate medical advice form the doctor.

Drug Warnings

Do not use Durogesic 50 mcg Patches if you are allergic to opioids or any ingredients of Durogesic 50 mcg Patches. Inform your doctor if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease or hypothyroidism (underactive thyroid). Do not use Durogesic 50 mcg Patches for a prolonged time, Durogesic 50 mcg Patches contains fentanyl that may lead to mental or physical dependence on Durogesic 50 mcg Patches. Do not take Durogesic 50 mcg Patches if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Durogesic 50 mcg Patches is not recommended for children below 18 years of age. Do not use this medicine if you have used an MAO inhibitor in the past 14 days, as a dangerous drug interaction could occur. Durogesic 50 mcg Patches should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Avoid consuming alcohol while on this medication, as it can lead to excessive sleepiness. Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with Durogesic 50 mcg Patches, especially in people affected with high blood pressure and a history of heart failure.

Drug-Drug Interactions

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FentanylLinezolid
Critical
FentanylMifepristone
Critical

Drug-Drug Interactions

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FentanylLinezolid
Critical
How does the drug interact with Durogesic 50 mcg Patches 3's:
Taking Linezolid with Durogesic 50 mcg Patches 3's may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Linezolid and Durogesic 50 mcg Patches 3's, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, muscle pain, stomach cramps, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
FentanylMifepristone
Critical
How does the drug interact with Durogesic 50 mcg Patches 3's:
Taking Durogesic 50 mcg Patches 3's and mifepristone may significantly increase the blood levels of Durogesic 50 mcg Patches 3's, which may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between mifepristone and Durogesic 50 mcg Patches 3's, they can be taken together if advised by a doctor. Do not stop using any medications without talking to your doctor.
FentanylSafinamide
Critical
How does the drug interact with Durogesic 50 mcg Patches 3's:
Taking Safinamide with Durogesic 50 mcg Patches 3's can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Durogesic 50 mcg Patches 3's is not recommended as it can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, muscle pain, stomach cramps, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
FentanylMeprobamate
Severe
How does the drug interact with Durogesic 50 mcg Patches 3's:
Combining Meprobamate with Durogesic 50 mcg Patches 3's can increase the risk of CNS depression.

How to manage the interaction:
Co-administration of Meprobamate with Durogesic 50 mcg Patches 3's can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor immediately if you have trouble breathing, loss of balance, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
FentanylDiazepam
Severe
How does the drug interact with Durogesic 50 mcg Patches 3's:
Taking Diazepam and Durogesic 50 mcg Patches 3's together can increase the risk of side effects.

How to manage the interaction:
Although taking Durogesic 50 mcg Patches 3's together with Diazepam can result in an interaction, they can be taken together if prescribed by your doctor. However, consult a doctor if you have sleepiness, difficulty concentrating, and impaired judgment. Do not stop taking any medication without consulting your doctor.
FentanylModafinil
Severe
How does the drug interact with Durogesic 50 mcg Patches 3's:
Coadministration of Durogesic 50 mcg Patches 3's and modafinil may reduce the blood levels of Durogesic 50 mcg Patches 3's, which may make the medication less effective in treating your pain.

How to manage the interaction:
Although taking Durogesic 50 mcg Patches 3's together with modafinil can result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience watery eyes, sneezing, excessive sweating, fever, rapid heartbeat, body aches, abdominal cramping, vomiting, or diarrhea. Do not stop taking any medication without consulting your doctor.
FentanylBaclofen
Severe
How does the drug interact with Durogesic 50 mcg Patches 3's:
Co-administration of Durogesic 50 mcg Patches 3's and baclofen can increase sedation and may lead to respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although taking Durogesic 50 mcg Patches 3's and baclofen together can result in an interaction, they can be taken if prescribed by a doctor. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
FentanylBosentan
Severe
How does the drug interact with Durogesic 50 mcg Patches 3's:
Taking Durogesic 50 mcg Patches 3's with bosentan can lower the levels of Durogesic 50 mcg Patches 3's in the blood, which may decrease the effectiveness of the medication.

How to manage the interaction:
Although taking Bosentan and Durogesic 50 mcg Patches 3's together can result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience a runny nose, excessive sweating, fever, body aches, abdominal cramping, vomiting, or diarrhoea. Do not stop using any medications without consulting a doctor.
FentanylNafcillin
Severe
How does the drug interact with Durogesic 50 mcg Patches 3's:
Coadministration of Durogesic 50 mcg Patches 3's and nafcillin may reduce the blood levels of Durogesic 50 mcg Patches 3's, which may make the medication less effective in treating your pain.

How to manage the interaction:
Although there is an interaction between Durogesic 50 mcg Patches 3's and nafcillin, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience watery eyes, sneezing, excessive sweating, fever, rapid heartbeat, body aches, abdominal pain, vomiting, or diarrhea. Do not stop taking any medication without consulting your doctor.
FentanylAtracurium
Severe
How does the drug interact with Durogesic 50 mcg Patches 3's:
Combining Atracurium with Durogesic 50 mcg Patches 3's can increase the risk of irregular heart rhythm and low blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Atracurium and Durogesic 50 mcg Patches 3's, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
  • In the chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that have a minimum level of chemicals called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible, and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis.  Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating many simple carbohydrates in processed foods.

Habit Forming

No

Therapeutic Class

NARCOTIC (OPIOID) ANALGESIC

Durogesic 50 mcg Patches Substitute

Substitutes safety advice
  • Trofentyl 50 mcg Injection 10 ml

    11.97per tablet
  • Rufenyl 50 mcg Injection 2 ml

    31.65per tablet
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Alcohol

Caution

Consumption of alcohol while using Durogesic 50 mcg Patches may cause dizziness or drowsiness. Besides this, it can also damage your liver if used for a longer duration. So, avoid or limit intake of alcoholic beverages while on treatment with Durogesic 50 mcg Patches.

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Pregnancy

Caution

Let your doctor know if you are pregnant or intend to become pregnant. Regular usage of Durogesic 50 mcg Patches during pregnancy increases the likelihood that your foetus may have potentially fatal withdrawal symptoms. If your infant exhibits symptoms like hyperactivity, disturbed sleep, high-pitched crying, excessive shaking of a body part, vomiting, diarrhoea, or failure to gain weight, contact your doctor immediately.

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Breast Feeding

Caution

It may be unsafe to use during breastfeeding as it may cause sleepiness and decreased heart rate in the breastfeeding child. Hence, if you are a breastfeeding mother, inform your doctor before taking Durogesic 50 mcg Patches.

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Driving

Caution

Durogesic 50 mcg Patches is known to cause dizziness, sleepiness, and drowsiness. So, do not drive or operate any machinery until you are alert.

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Liver

Caution

Durogesic 50 mcg Patches to be used with caution in case of liver condition. If you have pre-existing or a history of liver disease, inform your doctor before receiving this medicine.

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Kidney

Caution

Durogesic 50 mcg Patches to be used with caution in case of kidney condition. If you have pre-existing or a history of kidney disease, inform your doctor before receiving this medicine.

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Children

Unsafe

Durogesic 50 mcg Patches is not recommended to be used in children below the age of 18 years.

FAQs

Durogesic 50 mcg Patches is used to treat Pain.
Durogesic 50 mcg Patches contains Fentanyl which works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.
Yes, Durogesic 50 mcg Patches occasionally could cause you to breathe more slowly than normal or might make you feel out of breath. If you do, please call your doctor right away. Additionally, before using Durogesic 50 mcg Patches, patients with any respiratory issues should let their doctor know.
Durogesic 50 mcg Patches is a habit-forming drug. It is not likely to be addictive if you take it for 2-4 weeks. However, if the doctor has prescribed you for more than 2-4 weeks, your doctor may reduce your dose before completely stopping it.
Elderly patients (aged more than 65 years) are more likely to have confusion and sleepiness or age-related health issues, which may require caution and an adjustment in the dose for patients receiving Durogesic 50 mcg Patches. So, it is better to consult a doctor before taking this medicine.

Country of origin

India

Manufacturer/Marketer address

Corporate Communications, Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Other Info - DUR0038

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