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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 30, 2024 | 5:51 AM IST

Retisphere 0.025% Cream is used to treat acne (pimples) and sun-damaged skin. It contains Tretinoin, (a form of vitamin A) that loosens and unblocks pores on the skin's surface by reducing the oil secretion in the skin. This prevents the formation of pimples, whiteheads, and blackheads. Some people may experience side effects such as dry skin, peeling, redness, burning, itching, or stinging sensation of the skin. Avoid sun exposure while using this medicine, as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use a sunscreen lotion while going out to protect your skin from sunburn.

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Manufacturer/Marketer

Amwill Healthcare Pvt Ltd

Consume Type

TOPICAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Retisphere 0.025% Cream

Retisphere 0.025% Cream is used to treat acne (pimples) and sun-damaged skin. Acne is a skin condition that is common and occurs when hair follicles are blocked with dead skin cells and oil.

Retisphere 0.025% Cream contains tretinoin, also known as retinoic acid (a form of vitamin A), that loosens and unblocks pores on the skin’s surface by reducing the oil secretion in the skin. This prevents the formation of pimples, whiteheads, and blackheads.

Retisphere 0.025% Cream is for external use only. Your doctor will advise you on how often you use Retisphere 0.025% Cream based on your medical condition. Avoid contact of Retisphere 0.025% Cream with nose, mouth, eyes, ears, or vagina. In case Retisphere 0.025% Cream comes in contact with these areas accidentally, rinse with water thoroughly. Some people may experience dry skin, peeling, redness, burning, itching, or stinging sensation of the skin. Most of these side effects of Retisphere 0.025% Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Retisphere 0.025% Cream or any other medicines, please tell your doctor. If you are pregnant, a nursing mother, or planning for pregnancy, it is advised to consult a doctor before using Retisphere 0.025% Cream. Avoid sun exposure while using Retisphere 0.025% Cream as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use a sunscreen lotion (SPF) while going out to protect your skin from sunburn. Do not apply Retisphere 0.025% Cream in larger amounts than prescribed, as it does not give quick or better results but causes peeling, marked redness, or skin discomfort. Patients with a history of depression, eczema, history of skin cancer, and fish allergies should use Retisphere 0.025% Cream with caution.

Uses of Retisphere 0.025% Cream

Treatment of Acne, Wrinkles

Medicinal Benefits

Retisphere 0.025% Cream is a form of vitamin A (retinoid) that loosens and unblocks pores on the skin’s surface by reducing the oil secretion in the skin. This prevents the formation of pimples, whiteheads, and blackheads.

Directions for Use

Wash your hands before and after applying Retisphere 0.025% Cream. Before using it, try to clean and dry the affected skin area. Applying Retisphere 0.025% Cream to wet skin may cause skin irritation, so try not to wash the treated area. Also, do not apply other skin products for at least 1 hour after applying Retisphere 0.025% Cream. Wash the face with mild soap and pat the skin dry. Take a small pearl-sized amount of Retisphere 0.025% Cream on the fingertip and apply it on the clean and dry affected area once a day in the evening. Avoid contact of Retisphere 0.025% Cream with nose, mouth, eyes, ears or vagina. In case Retisphere 0.025% Cream comes in contact with these areas accidentally, rinse with water thoroughly.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Retisphere 0.025% Cream

  • Dry skin
  • Peeling
  • Skin redness
  • Burning
  • Itching
  • Stinging sensation

Drug Warnings

If you are allergic to tretinoin or any other medicines, please inform your doctor. If skin irritation, redness, burning, or stinging sensation worsens at the site of application, stop using Retisphere 0.025% Cream and consult a doctor. If you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Retisphere 0.025% Cream. Avoid sun exposure, use a sunscreen lotion and wear protective clothing while going out in the sun as Retisphere 0.025% Cream may make the skin more sensitive to the sun. Do not apply Retisphere 0.025% Cream in large amounts than prescribed as it does not give quick or better results but causes peeling, marked redness, or skin discomfort. Use Retisphere 0.025% Cream with caution when used together with medicated or abrasive soaps, cleansers, shampoos, astringents, products with high concentrations of alcohol, electrolysis, hair depilatories, or waxes or topical medications as they may increase skin irritation.

Drug Interactions

Drug-Drug Interaction: Retisphere 0.025% Cream may interact with vitamin A-related drugs known as retinoids (isotretinoin), photosensitizing agents (aminolevulinic acid, methoxsalen, porfirmer, verteporfin), sensitizer (methyl aminolevulinate), keratolytic agents (benzoyl peroxide, salicylic acid, sulfur), antiseptic (resorcinol).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have eczema (itchy, swelling of the skin) or any other skin condition, inform your doctor before taking Retisphere 0.025% Cream.

Drug-Drug Interactions Checker List

  • ISOTRETINOIN
  • AMINOLEVULINIC ACID
  • METHOXSALEN
  • PORFIRMER
  • VERTEPORFIN
  • METHYL AMINOLEVULINATE
  • BENZOYL PEROXIDE
  • SALICYCLIC ACID
  • SULFUR
  • RESORCINOL

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid sun exposure while using Retisphere 0.025% Cream as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
  • Regular exercise can improve your mood and self-esteem, though it doesn’t clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.
  • Do regular hair wash and avoid hair falling across the face.
  • Use water-based cosmetic products and remove the makeup completely before going to bed.

Special Advise

  • ​​​​​​Do not apply Retisphere 0.025% Cream in larger amounts than prescribed, as this does not give quick or better results but causes peeling, marked redness, or skin discomfort.
  • Do not squeeze spots or try to clean blackheads, as it may worsen them and cause permanent scarring.

Disease/Condition Glossary

Acne: Acne is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads and blackheads. Acne affects people of all ages but is most common among teenagers. The symptoms of acne include pus-filled pimples, uninflamed (not swollen) blackheads, and red, large and tender bumps.

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Alcohol

Caution

Interaction of alcohol with Retisphere 0.025% Cream is unknown. Please consult a doctor before consuming alcohol while using Retisphere 0.025% Cream.

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Pregnancy

Unsafe

Retisphere 0.025% Cream is Category C pregnancy drug and is considered unsafe for pregnant women. Therefore, if you are pregnant, inform your doctor before using Retisphere 0.025% Cream.

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Breast Feeding

Caution

It is unknown whether Retisphere 0.025% Cream is excreted in human milk. Please consult a doctor before using Retisphere 0.025% Cream while breastfeeding.

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Driving

Safe if prescribed

Retisphere 0.025% Cream usually does not affect your ability to drive or operate machinery.

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Liver

Caution

If you have any concerns regarding the use of Retisphere 0.025% Cream in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Retisphere 0.025% Cream in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Retisphere 0.025% Cream is not recommended for children below 18 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

No.157, 1St Floor, 2Nd Main Road, 3Rd Cross, Chamrajpet, Bangalore, Karnataka 560018 €“ India
Other Info - RET0134

Author Details

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FAQs

Retisphere 0.025% Cream is primarily used to treat acne (pimples) and sun-damaged skin.
Retisphere 0.025% Cream may increase the skin sensitivity to sunlight in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen with a minimum SPF 15 and wear protective clothing while going out to prevent sunburn.
You are recommended to use cosmetics after 1 hour of applying Retisphere 0.025% Cream but avoid cosmetics with a strong drying effect as they may increase skin irritation. If you are using any cosmetics, clean your face before applying Retisphere 0.025% Cream again.
Yes, Retisphere 0.025% Cream may cause skin irritation, burning sensation or itching at the site of application. Extreme weather conditions such as cold or wind may cause more irritation in patients using Retisphere 0.025% Cream containing products. However, if the irritation worsens, stop using Retisphere 0.025% Cream and consult a doctor.
You are advised to use moisturizers in the morning every day to prevent dryness in the treated areas.
Retisphere 0.025% Cream does not remove wrinkles completely or repair skin damaged by the sun. Retisphere 0.025% Cream may reduce fine wrinkles, especially when used along with other skincare products.
You are recommended to use Retisphere 0.025% Cream for as long as your doctor has prescribed it. However, the course of treatment with Retisphere 0.025% Cream takes up to 6 months for effective results.
Acne is a skin condition that is common and occurs when hair follicles are blocked with dead skin cells and oil.
Retisphere 0.025% Cream increases cell turnover on your skin, which can promote new cell growth at the site of your scarring. As a result, it may help to reduce acne scars.
Limited research available. So, seek medical attention from your dermatologist.
Retisphere 0.025% Cream can be a safe, effective treatment option for acne.
Retisphere 0.025% Cream is Category C pregnancy drug and is considered unsafe for pregnant women. Therefore, if you are pregnant, inform your doctor before using Retisphere 0.025% Cream.
Skin peeling occurs for a variety of reasons. First, tretinoin is an exfoliator. When you apply tretinoin gel or cream to your face, your body speeds up the rate at which it replaces old skin with new skin, shedding the old layer of skin in the process. Second, tretinoin can increase your skin’s sensitivity to sunlight, making it more likely that your facial skin could become sunburned and peel off naturally after sun exposure. Using a moisturizer and avoiding sunlight exposure is recommended to manage skin peeling.

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