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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Rasby Injection is used to treat high levels of uric acid (a natural substance that builds up in the blood as tumors break down) in people with certain types of cancer who are being treated with chemotherapy medications. It works by breaking down uric acid so that the body can eliminate it. Rasby Injection may cause nausea, vomiting, constipation, diarrhoea, abdominal pain, mouth sores, throat pain, headache, anxiety, joint pain and fever.

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Whats That

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Composition :

RASBURICASE-1.5MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Rasby Injection

Rasby Injection is a recombinant version of the enzyme urate oxidase used to reduce uric acid levels in patients with leukaemia, lymphoma, and solid tumor malignancies receiving anti-cancer therapy. Leukaemia, or blood cancer, is a cancer of blood cells or blood-forming tissues. Lymphoma is a cancer of the lymphatic system.

Rasby Injection contains Rasburicase, which belongs to the class of recombinant urate-oxidase enzymes. It works by metabolising the recombinant urate oxidase enzyme and thus helps clear the uric acid levels.

Rasby Injection may cause certain side effects such as vomiting, nausea, fever, constipation, diarrhoea, oedema, headache, abdominal pain, anxiety, and injection site reactions. Most of these side effects of Rasby Injection do not require medical attention and gradually resolve over time. A trained healthcare professional will administer Rasby Injection. Hence, do not self-administer.

If you are allergic to Rasby Injection, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with Rasby Injection. Rasby Injection is contraindicated for pregnant women and breastfeeding women due to serious fetal harm. Hence, inform your doctor if you are pregnant or planning to become pregnant. Inform your doctor if you have/had kidney or liver disease.

Uses of Rasby Injection

Helps remove excess uric acid levels in patients with leukaemia, lymphoma, and solid tumor malignancies.

Directions for Use

Your oncology doctor will administer Rasby Injection. Hence, do not self-administer.

Medicinal Benefits

Rasby Injection contains Rasburicase, which belongs to the recombinant urate-oxidase class of drugs. It works directly by metabolising the recombinant urate oxidase enzyme. This converts into allantoin, which is more soluble in urine. It makes it easier for the kidneys to excrete uric acid from the body.

How Rasby Injection Works

Rasby Injection contains Rasburicase, which belongs to the class of recombinant urate-oxidase enzymes. It works by metabolising the recombinant urate oxidase enzyme and thus helps clear the uric acid levels.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rasby Injection

  • Vomiting
  • Nausea
  • Loss of appetite
  • Diarrhoea
  • Dizziness
  • Anxiety
  • Stomach pain
  • Headache
  • Peripheral edema
  • Injection site reactions
  • Pain at the site of injection

What if I have taken an overdose of Rasby Injection

As Rasby Injection is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Inform your doctor if you develop any allergic reactions after receiving Rasby Injection. Inform your doctor about your complete medical and medication history before starting treatment with Rasby Injection. Rasby Injection is contraindicated for pregnant women and breastfeeding women due to serious fetal harm. Hence, inform your doctor if you are pregnant or planning to become pregnant. Rasby Injection may cause severe hypersensitivity reactions, anaphylactic reactions, methemoglobinemia, and hemolysis in some patients. Hence, inform your doctor if you have/had any pre-existing liver or kidney disease. Avoid alcohol consumption with Rasby Injection as it may cause serious side effects. Avoid breastfeeding while receiving Rasby Injection as it can cause harm to the baby. This medicine is contraindicated in patients with G6PD deficiency.

Drug-Drug Interactions

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RasburicaseSodium nitrite
Severe
RasburicaseBupivacaine
Severe

Drug-Drug Interactions

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RasburicaseSodium nitrite
Severe
How does the drug interact with Rasby Injection:
Taking Rasby Injection with chloroprocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Rasby Injection with Sodium nitrite can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting a doctor.
RasburicaseBupivacaine
Severe
How does the drug interact with Rasby Injection:
Taking Bupivacaine with Rasby Injection can increase the risk of methemoglobinemia(blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Bupivacaine with Rasby Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
RasburicaseLidocaine
Severe
How does the drug interact with Rasby Injection:
Taking Rasby Injection with Lidocaine can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Rasby Injection with Lidocaine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
RasburicaseRopivacaine
Severe
How does the drug interact with Rasby Injection:
Taking Rasby Injection with ropivacaine can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
There may be a possibility of interaction between Rasby Injection and Ropivacaine, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
RasburicasePrilocaine
Severe
How does the drug interact with Rasby Injection:
Combining Rasby Injection with Prilocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Rasby Injection and Prilocaine together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
RasburicaseEtidocaine
Severe
How does the drug interact with Rasby Injection:
Taking Rasby Injection with Etidocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Rasby Injection and Etidocaine, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakess, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without first talking to your doctor.
RasburicaseLevobupivacaine
Severe
How does the drug interact with Rasby Injection:
Taking Rasby Injection with Levobupivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Rasby Injection with Levobupivacaine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
RasburicaseTetracaine
Severe
How does the drug interact with Rasby Injection:
Taking Rasby Injection with Tetracaine can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Rasby Injection with Tetracaine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
RasburicaseMepivacaine
Severe
How does the drug interact with Rasby Injection:
Taking Rasby Injection with Mepivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Rasby Injection with Mepivacaine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
RasburicaseChloroprocaine
Severe
How does the drug interact with Rasby Injection:
Taking Rasby Injection with Chloroprocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Rasby Injection and Chloroprocaine, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Rasby Injection as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Quit smoking.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Rasby Injection Substitute

Substitutes safety advice
  • Rasburnat 1.5Mg Inj

    by AYUR

    7216.00per tablet
  • Rascase Injection 1's

    by Others

    8659.20per tablet
  • Rasuric Injection 1's

    by Others

    6970.00per tablet
  • Rasbelon Injection 1's

    by Others

    10086.00per tablet
  • Rasbase 1.5 mg Injection 1's

    by Others

    10496.00per tablet
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Alcohol

Consult your doctor

It is unknown whether Rasby Injection interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Rasby Injection. You should not become pregnant while on treatment with Rasby Injection.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. If you are breastfeeding, inform your doctor before receiving Rasby Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Caution

Rasby Injection is administered as a single dose in a hospital setting. however Rasby Injection may cause dizziness; therefore, avoid driving vehicles or operating machinery until you return to normal.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Rasby Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Rasby Injection as it may lead to kidney failure. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

Please consult your doctor. Rasby Injection can be used in children if prescribed.

FAQs

Rasby Injection is used to help remove excess uric acid levels in patients with leukaemia, lymphoma, and solid tumour malignancies.

Rasby Injection contains Rasburicase, which works by metabolizing the recombinant urate oxidase enzyme and thus helps clear the uric acid levels.

Rasby Injection is known to cause severe hypersensitivity reactions, hemolysis, and methemoglobinemia in some patients. Hence, inform your doctor about your complete medical and medication history before starting the treatment.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - RAS0084

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